Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Tiratha Raj Singh"'
Autor:
Rohit Shukla, Anshuman Chandra, Anuj Kumar, Pallavi Kandpal, Himanshu Avashthi, Vijay Kumar Goel, Imteyaz Qamar, Nagendra Singh, David J. Kelvin, Tiratha Raj Singh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract In recent years, the outbreak of infectious disease caused by Zika Virus (ZIKV) has posed a major threat to global public health, calling for the development of therapeutics to treat ZIKV disease. Several possible druggable targets involved
Externí odkaz:
https://doaj.org/article/d9228957d8ee4565a4cf098b85e2c47a
Autor:
Ankita Singh, Tiratha Raj Singh
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 3, Iss 2, Pp 90-104 (2023)
Alzheimer’s disease (AD), which affects around twenty-seven million people globally, is an aging-related neurodegenerative condition characterized by the extracellular deposition of misfolded amyloid-β (Aβ) peptides and the intracellular producti
Externí odkaz:
https://doaj.org/article/f0f308c4b41140e7958e259f4501440b
Autor:
Sidharth Saxena, T. P. Krishna Murthy, C. R. Chandrashekhar, Lavan S. Patil, Abhinav Aditya, Rohit Shukla, Arvind Kumar Yadav, Tiratha Raj Singh, Mahesh Samantaray, Amutha Ramaswamy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Polymorphisms of Thiopurine S-methyltransferase (TPMT) are known to be associated with leukemia, inflammatory bowel diseases, and more. The objective of the present study was to identify novel deleterious missense SNPs of TPMT through a comp
Externí odkaz:
https://doaj.org/article/16ac48616fa243d5bd4bed1b4101570e
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Alzheimer’s disease (AD) is a neurological disorder caused by the abnormal accumulation of hyperphosphorylated proteins. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a dual phosphorylation enzyme which phosphorylates th
Externí odkaz:
https://doaj.org/article/88c58c8eeaaa4f9f9d26af6de2a79d44
Autor:
Rohit Shukla, Tiratha Raj Singh
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Alzheimer’s disease is a leading neurodegenerative disease worldwide and is the 6th leading cause of death in the USA. AD is a very complex disease and the drugs available in the market cannot fully cure it. The glycogen synthas
Externí odkaz:
https://doaj.org/article/59f93ff8f34e4337a9f0ab9f2e097664
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157031 (2016)
DNA repair mechanisms act as a warrior combating various damaging processes that ensue critical malignancies. DREMECELS was designed considering the malignancies with frequent alterations in DNA repair pathways, that is, colorectal and endometrial ca
Externí odkaz:
https://doaj.org/article/18032c144fb34aaba91f4c73a50f0e28
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133901 (2015)
For examining the intricate biological processes concerned with colorectal cancer (CRC), a systems biology approach integrating several biological components and other influencing factors is essential to understand. We performed a comprehensive syste
Externí odkaz:
https://doaj.org/article/c3a318fb16b24a2dbfe71048c46f0b07
Autor:
T. P. Krishna Murthy, Rohit Shukla, N. Durga Prasad, Praveen Swetha, S. Shreyas, Tiratha Raj Singh, Ramya Pattabiraman, Shishira S. Nair, Blessy B. Mathew, K. M. Kumar
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-15
Missense Non-synonymous single nucleotide polymorphisms (nsSNPs) of Galactose Mutarotase (GALM) are associated with the Novel type of Galactosemia (Galactosemia type 4) together with symptoms such as high blood galactose levels and eye cataracts. The
Autor:
Michel Arnaud Mbock, Raceline Gounoue Kamkumo, Rohit Shukla, William Feudjou Fouatio, Patrick Valère Tsouh Fokou, Florence Ngueguim Tsofack, Clarice Djouwoug Noussi, Rodrigue Fifen, Augustin Ephrem Nkengfack, Tiratha Raj Singh, Bruno Lenta Ndjakou, Norbert Sewald, Fabrice Fekam Boyom, Jean Justin Essia Ngang, Onana Boyomo, Theophile Dimo
ETHNOPHARMACOLOGICAL RELEVANCE: Detarium microcarpum is used to treat typhoid fever, a major public health problem, by indigenous population in Africa. Though its preventive activities have been documented, the curative effect is still to be confirme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdafd57714b9e31c182ad8ef1ede0215
https://doi.org/10.1016/j.jep.2023.116209
https://doi.org/10.1016/j.jep.2023.116209
Publikováno v:
Network Modeling Analysis in Health Informatics and Bioinformatics. 11