Zobrazeno 1 - 10
of 1 850
pro vyhledávání: '"Tirapazamine (TPZ)"'
Autor:
Ajnai, Giimel1,2,3 (AUTHOR) giimel.a@4hospital.mn, Cheng, Chun-Chia4 (AUTHOR) cccheng.biocompare@gmail.com, Kan, Tzu-Chun1 (AUTHOR) d119102016@tmu.edu.tw, Lu, Jeng-Wei5 (AUTHOR) jengweilu@gmail.com, Rahayu, Sri6 (AUTHOR) srirahayu@unj.ac.id, Chiu, Amy7 (AUTHOR) amchiu@coh.org, Chang, Jungshan1,8,9 (AUTHOR) js.chang@tmu.edu.tw
Publikováno v:
Pharmaceutics. Apr2022, Vol. 14 Issue 4, pN.PAG-N.PAG. 16p.
Autor:
Giimel Ajnai, Chun-Chia Cheng, Tzu-Chun Kan, Jeng-Wei Lu, Sri Rahayu, Amy Chiu, Jungshan Chang
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 847 (2022)
Tumor hypoxia is a hallmark of solid tumors and emerged as the therapeutic target for cancer treatments, such as a prodrug Tirapazamine (TPZ) activated in hypoxia. To increase tumor accumulation, gold nanoparticles (GNPs) were selected to conjugate w
Externí odkaz:
https://doaj.org/article/aad744552299478a892f4cfecdeccfa4
Akademický článek
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Publikováno v:
Pharmaceuticals, Vol 12, Iss 1, p 3 (2019)
Introduction: Benzotriazine-1,4-dioxides (BTDOs) such as tirapazamine (TPZ) and its derivatives act as radiosensitizers of hypoxic tissues. The benzotriazine-1-monoxide (BTMO) metabolite (SR 4317, TPZMO) of TPZ also has radiosensitizing properties, a
Externí odkaz:
https://doaj.org/article/7bad207505924d6a9de0269ae9ba4e73
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 12, Iss 1, p 3 (2019)
Volume 12
Issue 1
Pharmaceuticals, Vol 12, Iss 1, p 3 (2019)
Volume 12
Issue 1
Introduction: Benzotriazine-1,4-dioxides (BTDOs) such as tirapazamine (TPZ) and its derivatives act as radiosensitizers of hypoxic tissues. The benzotriazine-1-monoxide (BTMO) metabolite (SR 4317, TPZMO) of TPZ also has radiosensitizing properties, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc5b35cbeb0e4d263d171f25d76c525
http://europepmc.org/articles/PMC6469288
http://europepmc.org/articles/PMC6469288
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Fion L. Sung, Bo Hong, Chi Man Tsang, Vivian Wai Yan Lui, Anthony T.C. Chan, Suk Hang Cheng, Edwin P. Hui, Margaret H.L. Ng, Sai Wah Tsao
Publikováno v:
Investigational New Drugs. 29:401-410
Hypoxia is commonly developed in solid tumors, which contributes to metastasis as well as radio- and chemo-resistance. Nasopharyngeal carcinoma (NPC) is a highly invasive and metastatic head and neck cancer prevalent in Southeast Asia with a high inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f4d8f6d720c29350ecc81d8b00f1fc
https://doi.org/10.1007/s10637-009-9356-z
https://doi.org/10.1007/s10637-009-9356-z
Autor:
Yingchao Hao, Yue Gao, Yu Fan, Changchang Zhang, Mengsi Zhan, Xueyan Cao, Xiangyang Shi, Rui Guo
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Chemodynamic therapy is a promising cancer treatment with specific therapeutic effect at tumor sites, as toxic hydroxyl radical (·OH) could only be generated by Fenton or Fenton-like reaction in the tumor microenvironment (TME) w
Externí odkaz:
https://doaj.org/article/fb25d46619fa48d3b4977248e159927a
Autor:
Zeng, Bowen1,2 (AUTHOR), Pian, Lina1,2,3 (AUTHOR), Liu, Yanhong1,2 (AUTHOR), Wang, Shuangqing1,2,4 (AUTHOR), Wang, Nuoya1,2,4 (AUTHOR), Liu, Chao1,2 (AUTHOR), Wu, Hao1,2 (AUTHOR), Wan, Hongshuang1,2 (AUTHOR), Chen, Liqing1,2 (AUTHOR), Huang, Wei1,2 (AUTHOR), Gao, Zhonggao1,2 (AUTHOR) zggao@imm.ac.cn, Yin, Xuezhe3 (AUTHOR) yinxz123@126.com, Jin, Mingji1,2 (AUTHOR) jinmingji@imm.ac.cn
Publikováno v:
Journal of Nanobiotechnology. 9/12/2024, Vol. 22 Issue 1, p1-19. 19p.