Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tira J Tan"'
Autor:
Trina Arifin, Whee Sze Ong, Yu Ling Juliana Chia, Agnes Lai Yin Chow, Anupama Roy Chowdhury, Johan Chan, Wei Chong Tan, Mothi Babu Ramalingam, Tanujaa Rajasekaran, Tira J Tan, Lalit Krishna, Olive Shu Jun Lai, Simon Chern Jian Chen, Ravindran Kanesvaran
Publikováno v:
Proceedings of Singapore Healthcare, Vol 33 (2024)
Background Geriatric assessment (GA) has been shown to be pivotal to the prognosis of elderly cancer patients. A G8 screening tool could act as a potential surrogate to identify patients who would benefit from further GA in a busy oncology clinic and
Externí odkaz:
https://doaj.org/article/3333b3c1ee1f4e54b3641c5f926fba16
Autor:
Ravit Geva, Jennifer Mataraza, Osama Rahma, Jason John Luke, Philippe L Bedard, Sarina A Piha-Paul, Angad Singh, Tira J Tan, Darren WT Lim, Cinta Hierro, Toshikiko Doi, Alexander Lesokhin, Javier Otero, Lisa Nardi, Alexandros Xyrafas, Xinhui Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Background GWN323 is an IgG1 monoclonal antibody (mAb) against the glucocorticoid-induced tumor necrosis factor receptor-related protein. This first-in-human, open-label phase I/Ib study aimed to investigate the safety and tolerability and to identif
Externí odkaz:
https://doaj.org/article/3cc27cd3ea53425da3baab2883f1afa6
Autor:
Tira J. Tan, W. X. Gladys Ang, Who-Whong Wang, Hui-Shan Chong, Sze Huey Tan, Rachael Cheong, John Whay-Kuang Chia, Nicholas L. Syn, Wai Ho Shuen, Rebecca Ba, Nivashini Kaliaperumal, Bijin Au, Richard Hopkins, Xinhua Li, Aaron C. Tan, Amanda O. L. Seet, John E. Connolly, Thaschawee Arkachaisri, Valerie Chew, Ahmad bin Mohamed Lajam, Dianyan Guo, Marvin Z. W. Chew, Martin Wasser, Pavanish Kumar, Salvatore Albani, Han Chong Toh
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Ad-sig-hMUC1/ecdCD40L is a recombinant adenovirus vaccine comprising human MUC1 antigen fused to the extracellular domain of the CD40 ligand. Here the authors report the result of a phase I clinical trial of Ad-sig-hMUC1/ecdCD40L in patients with adv
Externí odkaz:
https://doaj.org/article/bc9966f3f06642699fbd9cc02be4f7e3
Autor:
Zewen Zhang, Jun Ma, Jasmine Yun Ting Tan, Whee Sze Ong, Sulastri Kamis, Grace Yang, Benita Kiat Tee Tan, Veronique Kiak Mien Tan, Tira J. Tan
Publikováno v:
Cancer Research. 83:P4-07
Background: Non-metastatic breast cancers (BC) are increasing treated with neoadjuvant therapy (NAT). Complete pathological response (pCR) is associated with improved survival. Early identification of care needs during NAT is crucial. We report our i
Autor:
Wei Peng Yong, Felicia SW Teo, Lynette LS Teo, Matthew CH Ng, Tira J. Tan, Su Ying Low, Karmen Wong, Peter Ang, Su Pin Choo, Kim Hua Lee, Soo Chin Lee
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 18:805-815
Autor:
Tira J, Tan, J Lynn, Fink, Timothy K, Tay, Binny, Jaradi, Nathan, Stone, Paul, Waring, Kevin M, Koo, Puay Hoon, Tan, Daniel S, Tan, Rebecca A, Dent
Publikováno v:
JCO precision oncology. 6
Autor:
Sarah L. Sammons, Tira J. Tan, Young Hyunk Im, Tiffany A. Traina, Carey Anders, Ezekiel Renzulli, Sung-Bae Kim, Rebecca Dent
Publikováno v:
Cancer Research. 83:PD11-12
Introduction: A significant proportion of aTNBC patients carry homologous recombination defects associated with platinum sensitivity. Olaparib is an approved PARP inhibitor (PARPi) for germline BRCA (gBRCA) associated early and metastatic breast canc
Autor:
Joe Yeong, Denise Goh, Tira J. Tan, Benedict Tan, Huren Sivaraj, Valerie Koh, Jeffrey Chun Tatt Lim, Craig Ryan Joseph, Timothy Kwang Yong Tay, Jiangfeng Ye, Mai Chan Lau, Jason Yongsheng Chan, Jabed Iqbal, Cedric Chuan Young Ng, Bin Tean Teh, Rebecca Alexandra Dent, Puay Hoon Tan
Mutations in the PI3K pathway, particularly of PIK3CA, were reported to be intimately associated with triple negative breast cancer (TNBC) progression and development of treatment resistance. We profiled PIK3CA and other genes on 166 early-stage TNBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d646fa3232bfa7e7412fb7da96765ba0
https://doi.org/10.21203/rs.3.rs-1876811/v1
https://doi.org/10.21203/rs.3.rs-1876811/v1
Autor:
Siqing Fu, Gerald S. Falchook, Minal Barve, Meredith McKean, Tira J. Tan, Charlotte Lemech, Cheng E. Chee, Neyssa Marina, Giovanni Abbadessa, Robin Meng, Federico Rotolo, Hong Wang, Jason Deng, Wenting Wang, Rui Wang, Tarek Meniawy
Publikováno v:
Cancer Research. 83:2155-2155
Background: SAR’245 is a clinical-stage site-specific pegylated human IL-2 that blocks IL-2 alpha receptor binding but retains near-native binding affinity for beta/gamma IL-2 receptor subunits. When administered in preclinical models, a unique ‘
Autor:
Joe Yeong, Denise Goh, Tira J. Tan, Benedict Tan, Huren Sivaraj, Valerie Koh, Jeffrey Chun Tatt Lim, Craig Ryan Joseph, Jiangfeng Ye, Timothy Kwang Yong Tay, Mai Chan Lau, Jason Yongsheng Chan, Cedric Ng, Jabed Iqbal, Bin Tean Teh, Rebecca Alexandra Dent, Puay Hoon Tan
Publikováno v:
Modern Pathology. 36:100056