Limitations of gene editing assessments in human preimplantation embryos.

Autor: Liang D; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA.; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, No 218 Jixi Road, Hefei, 230022, Anhui, China., Mikhalchenko A; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Ma H; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Marti Gutierrez N; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Chen T; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China., Lee Y; Department of Biomedical Science, College of Life Science and CHA Advanced Research Institute, CHA University, Seongnam, Gyeonggi, 13488, Republic of Korea.; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea., Park SW; Center for Genome Engineering, Institute for Basic Science, 70, Yuseong-daero 1689-gil, Yuseong-gu, Daejeon, 34047, Republic of Korea.; School of Dentistry, Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju, 61186, Republic of Korea., Tippner-Hedges R; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Koski A; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Darby H; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Li Y; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Van Dyken C; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., Zhao H; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China., Wu K; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China., Zhang J; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China., Hou Z; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China., So S; Department of Biomedical Science, College of Life Science and CHA Advanced Research Institute, CHA University, Seongnam, Gyeonggi, 13488, Republic of Korea., Han J; Department of Biomedical Science, College of Life Science and CHA Advanced Research Institute, CHA University, Seongnam, Gyeonggi, 13488, Republic of Korea., Park J; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea., Kim CJ; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea., Zong K; Technology Center of Hefei Customs, Hefei, 230009, Anhui, China., Gong J; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI-Shenzhen, 518083, China.; China National GeneBank, BGI-Shenzhen, Shenzhen, 518120, China., Yuan Y; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI-Shenzhen, 518083, China.; China National GeneBank, BGI-Shenzhen, Shenzhen, 518120, China., Gu Y; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI-Shenzhen, 518083, China.; China National GeneBank, BGI-Shenzhen, Shenzhen, 518120, China., Shen Y; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI-Shenzhen, 518083, China.; China National GeneBank, BGI-Shenzhen, Shenzhen, 518120, China., Olson SB; Department of Molecular and Medical Genetics and Knight Diagnostic Laboratories, Oregon Health & Science University, Portland, OR, 97239, USA., Yang H; Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China., Battaglia D; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA., O'Leary T; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 Southwest, Bond Avenue, Portland, OR, 97239, USA., Krieg SA; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 Southwest, Bond Avenue, Portland, OR, 97239, USA., Lee DM; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 Southwest, Bond Avenue, Portland, OR, 97239, USA., Wu DH; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 Southwest, Bond Avenue, Portland, OR, 97239, USA., Duell PB; Knight Cardiovascular Institute, Oregon Health & Science University, 3181 Southwest, Sam Jackson Park Road, Portland, OR, 97239, USA., Kaul S; Knight Cardiovascular Institute, Oregon Health & Science University, 3181 Southwest, Sam Jackson Park Road, Portland, OR, 97239, USA., Kim JS; Center for Genome Engineering, Institute for Basic Science, 70, Yuseong-daero 1689-gil, Yuseong-gu, Daejeon, 34047, Republic of Korea.; Department of Chemistry, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul, 151-747, Republic of Korea., Heitner SB; Knight Cardiovascular Institute, Oregon Health & Science University, 3181 Southwest, Sam Jackson Park Road, Portland, OR, 97239, USA., Kang E; Department of Biomedical Science, College of Life Science and CHA Advanced Research Institute, CHA University, Seongnam, Gyeonggi, 13488, Republic of Korea.; Stem Cell Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea., Chen ZJ; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA.; Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250001, China.; Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200127, China., Amato P; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA.; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 Southwest, Bond Avenue, Portland, OR, 97239, USA., Mitalipov S; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 S. Bond Avenue, Portland, OR, 97239, USA. shoukhrat@gmail.com.

Publikováno v: Nature communications [Nat Commun] 2023 Mar 07; Vol. 14 (1), pp. 1219. Date of Electronic Publication: 2023 Mar 07.

Haploidy in somatic cells is induced by mature oocytes in mice.

Autor: Lee Y; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Gyeonggi, 13488, South Korea.; Center for Embryo and Stem Cell Research, CHA Advanced Research Institute, CHA University, Seongnam, Gyeonggi, 13488, South Korea., Trout A; The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, 10021, USA., Marti-Gutierrez N; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Kang S; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Gyeonggi, 13488, South Korea.; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology (AMIST), University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, South Korea., Xie P; The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, 10021, USA., Mikhalchenko A; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Kim B; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Gyeonggi, 13488, South Korea., Choi J; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Gyeonggi, 13488, South Korea.; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology (AMIST), University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, South Korea., So S; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Gyeonggi, 13488, South Korea.; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology (AMIST), University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, South Korea., Han J; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Gyeonggi, 13488, South Korea., Xu J; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA.; Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health and Science University, Portland, OR, 97006, USA.; Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, 97239, USA., Koski A; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Ma H; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Yoon JD; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Van Dyken C; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Darby H; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Liang D; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Li Y; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Tippner-Hedges R; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA., Xu F; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA.; Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, 97239, USA., Amato P; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA.; Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR, 97239, USA., Palermo GD; The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, 10021, USA. gdpalerm@med.cornell.edu., Mitalipov S; Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University, Portland, OR, 97239, USA. mitalipo@ohsu.edu., Kang E; Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Gyeonggi, 13488, South Korea. ekang@cha.ac.kr.; Center for Embryo and Stem Cell Research, CHA Advanced Research Institute, CHA University, Seongnam, Gyeonggi, 13488, South Korea. ekang@cha.ac.kr.

Publikováno v: Communications biology [Commun Biol] 2022 Jan 25; Vol. 5 (1), pp. 95. Date of Electronic Publication: 2022 Jan 25.

Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations.

Autor: Kang E; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA.; Stem Cell Center, ASAN Institute for Life Sciences, ASAN Medical Center, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea., Wu J; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California, 92037, USA., Gutierrez NM; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Koski A; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Tippner-Hedges R; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Agaronyan K; Department of Cell Biology School of Osteopathic Medicine, Rowan University, 2 Medical Center Drive, Stratford, New Jersey, 08084, USA., Platero-Luengo A; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California, 92037, USA., Martinez-Redondo P; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California, 92037, USA., Ma H; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Lee Y; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA.; Stem Cell Center, ASAN Institute for Life Sciences, ASAN Medical Center, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea., Hayama T; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Van Dyken C; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Wang X; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio, 45229, USA., Luo S; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio, 45229, USA., Ahmed R; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Li Y; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Ji D; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Reproductive Medical Centre, Anhui Medical University, No 218, Jixi Rd, Shushan District, Heifei, Anhui, 230022, China., Kayali R; IviGen Los Angeles, 406 Amapola Avenue, Suite 215, Torrance, California, 90501, USA., Cinnioglu C; IviGen Los Angeles, 406 Amapola Avenue, Suite 215, Torrance, California, 90501, USA., Olson S; Research Cytogenetics Laboratory, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA., Jensen J; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA., Battaglia D; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA., Lee D; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA., Wu D; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA., Huang T; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio, 45229, USA., Wolf DP; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA., Temiakov D; Department of Cell Biology School of Osteopathic Medicine, Rowan University, 2 Medical Center Drive, Stratford, New Jersey, 08084, USA., Belmonte JCI; Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California, 92037, USA., Amato P; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA. amatop@ohsu.edu., Mitalipov S; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA. mitalipo@ohsu.edu.; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USA. mitalipo@ohsu.edu.; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA. mitalipo@ohsu.edu.; Knight Cardiovascular Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon, 97239, USA. mitalipo@ohsu.edu.; Department of Biomedical Engineering, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, Oregon, 97239, USA. mitalipo@ohsu.edu.

Publikováno v: Nature [Nature] 2019 Mar; Vol. 567 (7747), pp. E5-E9.

Functional Human Oocytes Generated by Transfer of Polar Body Genomes.

Autor: Ma H; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., O'Neil RC; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Bioinformatics Program, University of California at San Diego, La Jolla, CA 92093, USA., Marti Gutierrez N; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Hariharan M; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA., Zhang ZZ; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA., He Y; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Bioinformatics Program, University of California at San Diego, La Jolla, CA 92093, USA., Cinnioglu C; IviGen Los Angeles, Torrance, CA 90501, USA., Kayali R; IviGen Los Angeles, Torrance, CA 90501, USA., Kang E; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Lee Y; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Hayama T; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Koski A; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Nery J; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA., Castanon R; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA., Tippner-Hedges R; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Ahmed R; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Van Dyken C; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Li Y; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Olson S; Department of Molecular and Medical Genetics, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA., Battaglia D; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR 97239, USA., Lee DM; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR 97239, USA., Wu DH; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR 97239, USA., Amato P; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR 97239, USA., Wolf DP; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA., Ecker JR; Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA; Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address: ecker@salk.edu., Mitalipov S; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR 97239, USA; Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: mitalipo@ohsu.edu.

Publikováno v: Cell stem cell [Cell Stem Cell] 2017 Jan 05; Vol. 20 (1), pp. 112-119. Date of Electronic Publication: 2016 Nov 10.

Incompatibility between Nuclear and Mitochondrial Genomes Contributes to an Interspecies Reproductive Barrier.

Autor: Ma H; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Marti Gutierrez N; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Morey R; Department of Reproductive Medicine, University of California, San Diego, Sanford Consortium for Regenerative Medicine, 2880 Torrey Pines Scenic Drive, La Jolla, CA 92037, USA., Van Dyken C; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Kang E; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Hayama T; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Lee Y; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Li Y; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Tippner-Hedges R; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Wolf DP; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA., Laurent LC; Department of Reproductive Medicine, University of California, San Diego, Sanford Consortium for Regenerative Medicine, 2880 Torrey Pines Scenic Drive, La Jolla, CA 92037, USA., Mitalipov S; Center for Embryonic Cell and Gene Therapy, Oregon Health & Science University, 3303 SW Bond Avenue, Portland, OR 97239, USA; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA; Knight Cardiovascular Institute and Departments of Obstetrics and Gynecology, Molecular and Medical Genetics, and Biomedical Engineering, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA. Electronic address: mitalipo@ohsu.edu.

Publikováno v: Cell metabolism [Cell Metab] 2016 Aug 09; Vol. 24 (2), pp. 283-94. Date of Electronic Publication: 2016 Jul 14.