Propionate catabolism by CD-associated adherent-invasive E. coli counteracts its anti-inflammatory effect

Autor: Allison Agus, Damien Richard, Tiphanie Faïs, Emilie Vazeille, Mélissa Chervy, Virginie Bonnin, Guillaume Dalmasso, Jérémy Denizot, Elisabeth Billard, Richard Bonnet, Anthony Buisson, Nicolas Barnich, Julien Delmas

Publikováno v: Gut Microbes, Vol 13, Iss 1 (2021)

Crohn’s disease (CD) is a chronic and disabling inflammatory disorder of the gut that is profoundly influenced by intestinal microbiota composition, host genetics and environmental factors. Several groups worldwide have described an imbalance of th

Externí odkaz: https://doaj.org/article/dcc6ad68757f475ba741a4d8ef5e7f99

Colibactin: More Than a New Bacterial Toxin

Autor: Tiphanie Faïs, Julien Delmas, Nicolas Barnich, Richard Bonnet, Guillaume Dalmasso

Publikováno v: Toxins, Vol 10, Iss 4, p 151 (2018)

Cyclomodulins are bacterial toxins that interfere with the eukaryotic cell cycle. A new cyclomodulin called colibactin, which is synthetized by the pks genomic island, was discovered in 2006. Despite many efforts, colibactin has not yet been purified

Externí odkaz: https://doaj.org/article/618d93b9f54c4de6ba46b42913c0b2f3

Yersiniabactin siderophore of Crohn’s disease-associated adherent-invasive Escherichia coli Is Involved in autophagy activation in host cells

Autor: Nicolas Barnich, Sébastien Massier, Richard Bonnet, Emilie Vazeille, Guillaume Dalmasso, Hang Thi Thu Nguyen, Tiphanie Faïs, Julien Delmas, Caroline Chevarin

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 22 (7), pp.1-17. ⟨10.3390/ijms22073512⟩
Volume 22
Issue 7
International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.1-17. ⟨10.3390/ijms22073512⟩
International Journal of Molecular Sciences, Vol 22, Iss 3512, p 3512 (2021)

International audience; Background: Adherent-invasive Escherichia coli (AIEC) have been implicated in the etiology of Crohn’s disease. The AIEC reference strain LF82 possesses a pathogenicity island similar to the high pathogenicity island of Yersi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db510b8b2134c43de93c97c733caef56
https://hal.inrae.fr/hal-03318629

Propionate catabolism by CD-associated adherent-invasive E. coli counteracts its anti-inflammatory effect

Autor: Emilie Vazeille, Virginie Bonnin, Richard Bonnet, Nicolas Barnich, Tiphanie Faïs, Damien Richard, Allison Agus, Elisabeth Billard, Julien Delmas, Anthony Buisson, Mélissa Chervy, Guillaume Dalmasso, Jérémy Denizot

Publikováno v: Gut Microbes, Vol 13, Iss 1 (2021)
Gut microbes
Gut microbes, Taylor & Francis, 2021, 13 (1), pp.1-19. ⟨10.1080/19490976.2020.1839318⟩
Gut microbes, 2021, 13 (1), pp.1-19. ⟨10.1080/19490976.2020.1839318⟩
Gut Microbes
article-version (VoR) Version of Record

International audience; Crohn's disease (CD) is a chronic and disabling inflammatory disorder of the gut that is profoundly influenced by intestinal microbiota composition, host genetics and environmental factors. Several groups worldwide have descri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3c0392e23a80b51acda4df4bc5c1ea
https://doaj.org/article/dcc6ad68757f475ba741a4d8ef5e7f99

Crohn’s Disease-Associated Adherent-Invasive Escherichia coli Manipulate Host Autophagy by Impairing SUMOylation

Autor: Sébastien Massier, Richard Bonnet, Julien Delmas, Guillaume Dalmasso, Tiphanie Faïs, Nicolas Barnich, Hang T T Nguyen

Publikováno v: Cells, Vol 8, Iss 1, p 35 (2019)
Cells
Cells, MDPI, 2019, 8 (1), pp.35. ⟨10.3390/cells8010035⟩
Volume 8
Issue 1

International audience; The intestinal mucosa of Crohn's disease (CD) patients is abnormally colonized with adherent-invasive Escherichia coli (AIEC) that are able to adhere to and to invade intestinal epithelial cells (IECs), to survive in macrophag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8a10fa9d20c8cba93d86f234fa4476
http://www.mdpi.com/2073-4409/8/1/35