Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tiphanie Courtiol"'
Autor:
Amélie S. Tora, Sara Cesarini, Heather McLean, Cyril Goudet, Tiphanie Courtiol, Nadia Oueslati, Bruno Commare, Berin Karaman, Thomas Bessiron, Francine Acher, Frédéric R. Leroux, Isabelle A. Lemasson, Delphine Rigault, Laetitia Mony, Hugues-Olivier Bertrand, Jean-Philippe Pin, Isabelle McCort-Tranchepain, Anne Goupil-Lamy, Isabelle Brabet, Hervé Daniel, Françoise Colobert, Chelliah Selvam, Alexandre Cabayé
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2018, 61 (5), pp.1969-1989. ⟨10.1021/acs.jmedchem.7b01438⟩
Journal of Medicinal Chemistry, American Chemical Society, 2018, 61 (5), pp.1969-1989. ⟨10.1021/acs.jmedchem.7b01438⟩
This work was supported by the by the Fondation de France (comite Parkinson), the Agence Nationale de la Recherche (ANR-05-NEUR-0121-02, ANR-07-NEURO-047-04, and ANR-08-NEUR-006-02 in the frame of ERA-NET NEURON and ANR-13-BSV1-0006), the Fondation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8135547c041835ec608d24f8a3198a92
https://hal.archives-ouvertes.fr/hal-02018007
https://hal.archives-ouvertes.fr/hal-02018007
Autor:
Delphine Rigault, Francine Acher, Nadia Oueslati, Hervé Daniel, Marianne Amalric, Isabelle Brabet, Jean-Philippe Pin, Heather McLean, Hugues-Olivier Bertrand, Tiphanie Courtiol, Bruno Vilar, Thomas Bessiron, Cyril Goudet, Thierry Deltheil
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. 〈10.1096/fj.11-195941〉
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, 2012, 26 (4), pp.1682-93. ⟨10.1096/fj.11-195941⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2012, 26 (4), pp.1682-93. 〈10.1096/fj.11-195941〉
International audience; Metabotropic glutamate (mGlu) receptors are promising targets to treat numerous brain disorders. So far, allosteric modulators are the only subtype selective ligands, but pure agonists still have strong therapeutic potential.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8983843f27bc58d9bb94a0657cb437b2
https://ora.ox.ac.uk/objects/uuid:ef698f81-75c9-4a7c-865a-379868656d73
https://ora.ox.ac.uk/objects/uuid:ef698f81-75c9-4a7c-865a-379868656d73
Autor:
Hugues-Olivier Bertrand, Tiphanie Courtiol, Sara Cesarini, Jean-Philippe Pin, Isabelle A. Lemasson, Isabelle Brabet, Nicolas Triballeau, Nadia Oueslati, Francine Acher, Delphine Rigault, Chelliah Selvam, Cyril Goudet
Publikováno v:
Journal of medicinal chemistry. 53(7)
(R)-PCEP (3-amino-3-carboxypropyl-2'-carboxyethyl phosphinic acid, 1), a new metabotropic glutamate receptor 4 (mGlu4R) agonist, was discovered in a previously reported virtual screening. The (S)-enantiomer and a series of derivatives were synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495d92182139f3faf4ebde0a427049c1
https://pubmed.ncbi.nlm.nih.gov/20218620
https://pubmed.ncbi.nlm.nih.gov/20218620
Publikováno v:
Tetrahedron Letters
Tetrahedron Letters, 2014, 55 (9), pp.1625-1627. ⟨10.1016/j.tetlet.2014.01.091⟩
Tetrahedron Letters, Elsevier, 2014, 55 (9), pp.1625-1627. ⟨10.1016/j.tetlet.2014.01.091⟩
Tetrahedron Letters, 2014, 55 (9), pp.1625-1627. ⟨10.1016/j.tetlet.2014.01.091⟩
Tetrahedron Letters, Elsevier, 2014, 55 (9), pp.1625-1627. ⟨10.1016/j.tetlet.2014.01.091⟩
International audience; A series of 9-(hetero)arylpurine derivatives has been prepared through N-arylation of 6-chloropurine with boronic acids in the presence of copper(II) acetate. Screening reaction conditions in terms of bases and solvents led to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9ec29a5af2e825f1fa7ab0f774244e
https://hal.science/hal-01968382
https://hal.science/hal-01968382