Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Tiong Wei Tan"'
Autor:
David P. Sheela, Beáta Sperlágh, Tiong Wei Tan, Mui Ling Khoo, Yi Yuan Chua, Ruth Deme, Balázs Balogh, Kálmán Magyar, Flóra Gölöncsér, Christina L. L. Chai, Paul B. Huleatt, Péter Mátyus, Han Kiat Ho, Rou Shen Liew
Publikováno v:
Journal of Medicinal Chemistry. 58:1400-1419
To develop novel neuroprotective agents, a library of novel arylalkenylpropargylamines was synthesized and tested for inhibitory activities against monoamine oxidases. From this, a number of highly potent and selective monoamine oxidase B inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079b2e214d527c4275d8ea0be05e54fd
https://doi.org/10.1021/jm501722s
https://doi.org/10.1021/jm501722s
Autor:
Sridhar Santhanakrishnan, Tiong Wei Tan, Eric Tam, Zhimei Li, Sze Yue Wong, Cheryl Zi Hui Lim, Yi Ling Goh, Christina L. L. Chai, Tuan Minh Nguyen, Esther H. Q. Ong, Jeffrey Hill, Qiang Yu, Haiyan Yang, Xia Jiang, Puay Leng Lee
Publikováno v:
ChemMedChem. 10:173-182
3-Deazaneplanocin A (DzNep) is a potential epigenetic drug for the treatment of various cancers. DzNep has been reported to deplete histone methylations, including oncogenic EZH2 complex, giving rise to epigenetic modifications that reactivate many s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d79c60c92330be31558cb330b5a6c1
https://doi.org/10.1002/cmdc.201402315
https://doi.org/10.1002/cmdc.201402315