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Akademický článek

Correlation Analyses Between Serum Interleukin-7, Interleukin-15 and Lactate Provide Insights Into Their Potential Roles in the Regulation of Inflammation in Elderly Septic Patients.

Autor: Zhao, Jingjing¹ (AUTHOR), Zhang, Ye^2,3 (AUTHOR), Wang, Jun-Yu^2,3 (AUTHOR), Wei, Bing^2,3 (AUTHOR) dr_weibing@126.com, Liu, Yu-Geng^1,2,3 (AUTHOR) yugeng_liu@126.com

Publikováno v: Biomarker Insights. 9/9/2024, p1-9. 9p.

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Sepsis-Induced Apoptosis Causes Progressive Profound Depletion of B and CD4+ T Lymphocytes in Humans

Autor: Robert Schmieg, Dale F. Osborne, Paul E. Swanson, J. P. Cobb, Timothy G. Buchman, Irene E. Karl, Tinsley Kw, Richard S. Hotchkiss, Bradley D. Freeman, J. J. Hui, Katherine Chang

Publikováno v: The Journal of Immunology. 166:6952-6963

Patients with sepsis have impaired host defenses that contribute to the lethality of the disorder. Recent work implicates lymphocyte apoptosis as a potential factor in the immunosuppression of sepsis. If lymphocyte apoptosis is an important mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436904b53f349c8c578e8e3a88ea9997
https://doi.org/10.4049/jimmunol.166.11.6952

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Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

Autor: Richard S. Hotchkiss, Paul E. Swanson, Timothy G. Buchman, Irene E. Karl, J. P. Cobb, Bradley D. Freeman, Matuschak Gm, Tinsley Kw

Publikováno v: Critical Care Medicine. 27:1230-1251

The purpose of this study was to determine whether apoptosis is a major mechanism of cell death in patients with sepsis. The activities of caspase-3 and the antiapoptotic protein, BCL-2, were investigated also.A prospective study of 20 patients who d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ad84a7a11fce9bf78963a19b77367f
https://doi.org/10.1097/00003246-199907000-00002

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Increased lymphoid tissue apoptosis in baboons with bacteremic shock

Autor: Pierre Lainée, Paul E. Swanson, Douglas J. Minnich, Philip A. Efron, J. Wagner, Lyle L. Moldawer, Tinsley Kw, Victor Monterroso, Katrien Lorré, Richard Hotchkiss

Publikováno v: Shock (Augusta, Ga.). 21(6)

The molecular mechanisms of immune cell apoptosis during sepsis remain unclear. Two young adult baboons (Papio sp.) received a lethal dose of live Escherichia coli and were sacrificed at either 16 (for animal welfare concerns) or 24 h post-septic sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0785df5a791ccb3b2974192b20e0649
https://pubmed.ncbi.nlm.nih.gov/15167687

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Akademický článek

Early absolute lymphocyte count was associated with one-year mortality in critically ill surgical patients: A propensity score-matching and weighting study.

Autor: Ho, Duc Trieu¹ (AUTHOR), Pham, The Thach¹ (AUTHOR), Wong, Li-Ting² (AUTHOR), Wu, Chieh-Liang^3,4 (AUTHOR), Chan, Ming-Cheng^3,4 (AUTHOR), Chao, Wen-Cheng^3,4,5 (AUTHOR) cwc081@hotmail.com

Publikováno v: PLoS ONE. 5/30/2024, Vol. 19 Issue 5, p1-15. 15p.

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