Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats.

Autor: Tinsley HN; Department of Biology Chemistry, Mathematics, and Computer Science, University of Montevallo, Montevallo, AL 35115, USA., Mathew B; Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA., Chen X; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA., Maxuitenko YY; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA., Li N; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35205, USA., Lowe WM; Department of Biology Chemistry, Mathematics, and Computer Science, University of Montevallo, Montevallo, AL 35115, USA., Whitt JD; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35205, USA., Zhang W; Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA., Gary BD; Drug Discovery Division, Southern Research, Birmingham, AL 35205, USA., Keeton AB; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA., Grizzle WE; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35205, USA.; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35205, USA., Grubbs CJ; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35205, USA., Reynolds RC; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35205, USA., Piazza GA; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, AL 36849, USA.

Publikováno v: Cancers [Cancers (Basel)] 2023 Jan 20; Vol. 15 (3). Date of Electronic Publication: 2023 Jan 20.

Ripped from the Headlines: Using Current Events and Deliberative Democracy to Improve Student Performance in and Perceptions of Nonmajors Biology Courses.

Autor: Tinsley HN; Department of Biology, Chemistry, and Mathematics, University of Montevallo, Montevallo, AL 35115.

Publikováno v: Journal of microbiology & biology education [J Microbiol Biol Educ] 2016 Dec 02; Vol. 17 (3), pp. 380-388. Date of Electronic Publication: 2016 Dec 02 (Print Publication: 2016).

cGMP signaling as a target for the prevention and treatment of breast cancer.

Autor: Windham PF; University of Montevallo, Department of Biology, Chemistry and Mathematics, Station 6480, Montevallo, AL 35115, USA., Tinsley HN; University of Montevallo, Department of Biology, Chemistry and Mathematics, Station 6480, Montevallo, AL 35115, USA. Electronic address: htinsley@montevallo.edu.

Publikováno v: Seminars in cancer biology [Semin Cancer Biol] 2015 Apr; Vol. 31, pp. 106-10. Date of Electronic Publication: 2014 Jun 24.

Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling.

Autor: Li N; Corresponding Author: Gary A. Piazza, Mitchell Cancer Institute, University of South Alabama, 1660 Springhill Avenue, Suite 3029, Mobile, AL 36604. gpiazza@usouthal.edu., Xi Y, Tinsley HN, Gurpinar E, Gary BD, Zhu B, Li Y, Chen X, Keeton AB, Abadi AH, Moyer MP, Grizzle WE, Chang WC, Clapper ML, Piazza GA

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2013 Sep; Vol. 12 (9), pp. 1848-59. Date of Electronic Publication: 2013 Jun 26.

Modulating the cyclic guanosine monophosphate substrate selectivity of the phosphodiesterase 3 inhibitors by pyridine, pyrido[2,3-d]pyrimidine derivatives and their effects upon the growth of HT-29 cancer cell line.

Autor: Abadi AH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Egypt. ashraf.abadi@guc.edu.eg, Hany MS, Elsharif SA, Eissa AA, Gary BD, Tinsley HN, Piazza GA

Publikováno v: Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2013; Vol. 61 (4), pp. 405-10.