Geranylgeranyl isoprenoids and hepatic Rap1a regulate basal and statin-induced expression of PCSK9

Autor: Wang, Yating, Tinsley, Brea, Spolitu, Stefano, Zadroga, John A., Agarwal, Heena, Sarecha, Amesh K., Ozcan, Lale

Publikováno v: In Journal of Lipid Research March 2024 65(3)

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Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first 6 months of the COVID-19 pandemic.

Autor: Lubin JH; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Zardecki C; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Dolan EM; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Lu C; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Shen Z; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Dutta S; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA., Westbrook JD; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA., Hudson BP; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Goodsell DS; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA.; The Scripps Research Institute, La Jolla, California, USA., Williams JK; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Voigt M; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Sarma V; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Xie L; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Venkatachalam T; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Arnold S; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Alfaro Alvarado LH; Grinnell College, Grinnell, Iowa, USA., Catalfano K; University of Notre Dame, Notre Dame, Indiana, USA., Khan A; University of Maryland Baltimore County, Baltimore, Maryland, USA., McCarthy E; Stevens Institute of Technology, Hoboken, New Jersey, USA., Staggers S; Frostburg State University, Frostburg, Maryland, USA., Tinsley B; Youngstown State University, Youngstown, Ohio, USA., Trudeau A; University of Central Florida, Orlando, Florida, USA., Singh J; New York City College of Technology, Brooklyn, New York, USA., Whitmore L; Howard University, Washington, District of Columbia, USA., Zheng H; Watchung Hills Regional High School, Warren, New Jersey, USA., Benedek M; Xavier University, Cincinnati, Ohio, USA., Currier J; Hope College, Holland, Michigan, USA., Dresel M; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Duvvuru A; Hope College, Holland, Michigan, USA., Dyszel B; Ursinus College, Collegeville, Pennsylvania, USA., Fingar E; SUNY Oswego, Oswego, New York, USA., Hennen EM; Roger Williams University, Bristol, Rhode Island, USA., Kirsch M; SUNY Oswego, Oswego, New York, USA., Khan AA; SUNY Oswego, Oswego, New York, USA., Labrie-Cleary C; SUNY Oswego, Oswego, New York, USA., Laporte S; Brandeis University, Waltham, Massachusetts, USA., Lenkeit E; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Martin K; Ursinus College, Collegeville, Pennsylvania, USA., Orellana M; Hope College, Holland, Michigan, USA., Ortiz-Alvarez de la Campa M; University of Puerto Rico-Rio Piedras, San Juan, Puerto Rico., Paredes I; John Jay College, New York, New York, USA., Wheeler B; Grand View University, Des Moines, Iowa, USA., Rupert A; Grand View University, Des Moines, Iowa, USA., Sam A; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., See K; Rochester Institute of Technology, Rochester, New York, USA., Soto Zapata S; SUNY Oswego, Oswego, New York, USA., Craig PA; Rochester Institute of Technology, Rochester, New York, USA., Hall BL; Grand View University, Des Moines, Iowa, USA., Jiang J; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Koeppe JR; SUNY Oswego, Oswego, New York, USA., Mills SA; Xavier University, Cincinnati, Ohio, USA., Pikaart MJ; Hope College, Holland, Michigan, USA., Roberts R; Ursinus College, Collegeville, Pennsylvania, USA., Bromberg Y; Department of Biochemistry and Microbiology, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA., Hoyer JS; Department of Ecology, Evolution and Natural Resources, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA., Duffy S; Department of Ecology, Evolution and Natural Resources, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA., Tischfield J; Department of Genetics, Rutgers, The State University of New Jersey, and Human Genetics Institute of New Jersey, Piscataway, New Jersey, USA., Ruiz FX; Center for Advanced Biotechnology and Medicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Arnold E; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Center for Advanced Biotechnology and Medicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Baum J; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA., Sandberg J; Center for Computational and Integrative Biology, Rutgers, The State University of New Jersey, Camden, New Jersey, USA., Brannigan G; Center for Computational and Integrative Biology, Rutgers, The State University of New Jersey, Camden, New Jersey, USA.; Department of Physics, Rutgers, The State University of New Jersey, Camden, New Jersey, USA., Khare SD; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA., Burley SK; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.; Rutgers Cancer Institute of New Jersey, Robert Wood Johnson Medical School, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, USA.; Research Collaboratory for Structural Bioinformatics Protein Data Bank, San Diego Supercomputer Center, University of California, San Diego, La Jolla, California, USA.

Publikováno v: Proteins [Proteins] 2022 May; Vol. 90 (5), pp. 1054-1080. Date of Electronic Publication: 2021 Oct 09.