Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Tinmarla F. Oo"'
Autor:
Patricia Tagliaferro, Tatyana Kareva, Tinmarla F. Oo, Olga Yarygina, Nikolai Kholodilov, Robert E. Burke
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 359-371 (2015)
Mutations in the gene for LRRK2 are the most common cause of familial Parkinson's disease (PD) and patients with these mutations manifest clinical features that are indistinguishable from those of the more common sporadic form. Thus, investigations o
Externí odkaz:
https://doaj.org/article/fe137f3579be4d7d9334cbc2107244fb
Autor:
Joanna M Dragich, Takaaki Kuwajima, Megumi Hirose-Ikeda, Michael S Yoon, Evelien Eenjes, Joan R Bosco, Leora M Fox, Alf H Lystad, Tinmarla F Oo, Olga Yarygina, Tomohiro Mita, Satoshi Waguri, Yoshinobu Ichimura, Masaaki Komatsu, Anne Simonsen, Robert E Burke, Carol A Mason, Ai Yamamoto
Publikováno v:
eLife, Vol 5 (2016)
The regulation of protein degradation is essential for maintaining the appropriate environment to coordinate complex cell signaling events and to promote cellular remodeling. The Autophagy linked FYVE protein (Alfy), previously identified as a molecu
Externí odkaz:
https://doaj.org/article/bebc1d11f6ea4e1fa0d10407c60fe990
Autor:
Sang Ryong Kim, Vincent Ries, Hsiao-Chun Cheng, Tatyana Kareva, Tinmarla F. Oo, W. Haung Yu, Karen Duff, Nikolai Kholodilov, Robert E. Burke
Publikováno v:
Neurobiology of Disease, Vol 44, Iss 2, Pp 215-222 (2011)
The mechanisms underlying the chronic neurodegeneration that occurs in Parkinson's disease (PD) are unknown. One emerging hypothesis is that neural systems deteriorate and eventually degenerate due to a primary failure of either extrinsic neurotrophi
Externí odkaz:
https://doaj.org/article/8cd59f1f030f417397036445fce9ad39
Autor:
Takaaki Kuwajima, Evelien Eenjes, Megumi Hirose-Ikeda, Joan R Bosco, Satoshi Waguri, Ai Yamamoto, Masaaki Komatsu, Robert E. Burke, Michael S Yoon, Carol A. Mason, Yoshinobu Ichimura, Tinmarla F. Oo, Joanna M. Dragich, Leora M. Fox, Olga Yarygina, Alf Håkon Lystad, Tomohiro Mita, Anne Simonsen
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
The regulation of protein degradation is essential for maintaining the appropriate environment to coordinate complex cell signaling events and to promote cellular remodeling. The Autophagy linked FYVE protein (Alfy), previously identified as a molecu
Autor:
Robert E. Burke, Joanna M. Dragich, Joan R Bosco, Takaaki Kuwajima, Leora M. Fox, Yoshinobu Ichimura, Alf Håkon Lystad, Anne Simonsen, Evelien Eenjes, Megumi Hirose-Ikeda, Satoshi Waguri, Olga Yarygina, Masaaki Komatsu, Carol A. Mason, Tomohiro Mita, Michael S Yoon, Tinmarla F. Oo, Ai Yamamoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79de7bd7757d13cb72e9e4c25c7a0f52
https://doi.org/10.7554/elife.14810.026
https://doi.org/10.7554/elife.14810.026
Autor:
Nikolai Kholodilov, Sang Ryong Kim, Tatyana Kareva, Karen Duff, Tinmarla F. Oo, W. Haung Yu, Hsiao-Chun Cheng, Robert E. Burke, Vincent Ries
Publikováno v:
Neurobiology of Disease, Vol 44, Iss 2, Pp 215-222 (2011)
The mechanisms underlying the chronic neurodegeneration that occurs in Parkinson's disease (PD) are unknown. One emerging hypothesis is that neural systems deteriorate and eventually degenerate due to a primary failure of either extrinsic neurotrophi
Autor:
Sang Ryong Kim, Xiqun Chen, Chuansong Wang, Olga Yarygina, Matthew J. During, Tatyana Kareva, Nikolai Kholodilov, Tinmarla F. Oo, Robert E. Burke
Publikováno v:
Annals of Neurology. 70:110-120
A prevailing concept in neuroscience has been that the adult mammalian central nervous system is incapable of restorative axon regeneration. Recent evidence, however, has suggested that reactivation of intrinsic cellular programs regulated by protein
Autor:
Amy Baohan, Robert E. Burke, Ross J. Bland, Hsiao-Chun Cheng, Tatyana Kareva, Nikolai Kholodilov, Vincent Ries, Matthew J. During, Tinmarla F. Oo, Margarita Rzhetskaya
Publikováno v:
Journal of Neurochemistry. 110:23-33
Following mitosis, specification and migration during embryogenesis, dopamine neurons of the mesencephalon undergo a postnatal naturally occurring cell death event that determines their final adult number, and a period of axonal growth that determine
Autor:
Robert M. Silva, Hsiao-Chun Cheng, Chia-Yi Kuan, Pasko Rakic, Richard A. Flavell, Margarita Rzhetskaya, Tinmarla F. Oo, Robert E. Burke, Nikolai Kholodilov, Vincent Ries
Publikováno v:
Journal of Neurochemistry. 107:1578-1588
Activation of c-jun N-terminal kinase (JNK) by the mitogen-activated protein kinase cascade has been shown to play an important role in the death of dopamine neurons of the substantia nigra, one of the principal neuronal populations affected in Parki
Publikováno v:
The Journal of Comparative Neurology. 484:57-67
There is increasing evidence that glial cell line-derived neurotrophic factor (GDNF) plays a role as a limiting, striatal target-derived neurotrophic factor for dopamine neurons of the substantia nigra pars compacta (SNpc) by regulating the magnitude