Výsledky vyhledávání - "Tinka Tuinstra"

Akademický článek

Differential regulation of the CXCR2 chemokine network in rat brain trauma: Implications for neuroimmune interactions and neuronal survival

Autor: Astrid Vallès, Lindsay Grijpink-Ongering, Freddy M. de Bree, Tinka Tuinstra, Eric Ronken

Publikováno v: Neurobiology of Disease, Vol 22, Iss 2, Pp 312-322 (2006)

Chemokine receptors represent promising targets to attenuate inflammatory responses and subsequent secondary damage after brain injury. We studied the response of the chemokines CXCL1/CINC-1 and CXCL2/MIP-2 and their receptors CXCR1 and CXCR2 after c

Externí odkaz: https://doaj.org/article/812e66c36f93450088a7dafb28fcbb04

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Profiling and Identification of Cerebrospinal Fluid Proteins in a Rat EAE Model of Multiple Sclerosis

Autor: Rainer Bischoff, Christoph Stingl, Theo M. Luider, Hans van Aken, Ernst Suidgeest, Therese Rosenling, Rogier Q. Hintzen, Peter Horvatovich, Frank Suits, Marcel P. Stoop, Christin Christin, Amos Attali, Tinka Tuinstra

Publikováno v: Journal of Proteome Research, 11(4), 2048-2060. NLM (Medline)
Journal of Proteome Research, 11(4), 2048-2060. American Chemical Society

The experimental autoimmune encephalomyelitis (EAR) model resembles certain aspects of multiple sclerosis (MScl), with common features such as motor dysfunction, axonal degradation, and infiltration of T-cells. We studied the cerebrospinal fluid (CSF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cce38ce1f78456bc40f5d65d9e8657
https://research.rug.nl/en/publications/64e46d1a-26ec-4832-b215-49e481b6989c

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Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications for neuroimmune interactions and neuronal survival

Autor: Lindsay Grijpink-Ongering, Tinka Tuinstra, Freddy M. de Bree, Astrid Vallès, Eric Ronken

Publikováno v: Neurobiology of Disease, 22, 312-322
Neurobiology of Disease, Vol 22, Iss 2, Pp 312-322 (2006)
Neurobiology of Disease, 22, 2, pp. 312-322

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3adcdf8cfcfea7eeb7038f692d836b
https://hdl.handle.net/2066/35929

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Metabolite profiling of small cerebrospinal fluid sample volumes with gas chromatography-mass spectrometry: Application to a rat model of multiple sclerosis

Autor: Bas Muilwijk, Ernst Suidgeest, M. Tienstra, Marek J. Noga, Theo M. Luider, I. Bobeldijk, H. van Aken, Amos Attali, Thomas Hankemeier, Tinka Tuinstra, Leon Coulier, Sabina Bijlsma

Publikováno v: Metabolomics, 1, 9, 78-87
Metabolomics, 9(1), 78-87

Analysis of metabolites in biofluids by gas chromatography-mass spectrometry (GC-MS) after oximation and silylation is a key method in metabolomics. The GC-MS method was modified by a modified vial design and sample work-up procedure in order to make

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce3c744e1876feab59501dbce863442
http://resolver.tudelft.nl/uuid:3aec1301-baa7-4643-87d3-a180a5e68de7

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Minocycline Effects on the Cerebrospinal Fluid Proteome of Experimental Autoimmune Encephalomyelitis Rats

Autor: Lennard J. M. Dekker, Hans van Aken, Tinka Tuinstra, Amos Attali, Ernst Suidgeest, Therese Rosenling, Rogier Q. Hintzen, Theo M. Luider, Christoph Stingl, Alain J. van Gool, Marcel P. Stoop, Roland J. W. Meesters, Rainer Bischoff

Publikováno v: Journal of Proteome Research, 11(8), 4315-4325. American Chemical Society
Journal of Proteome Research, 11, 8, pp. 4315-25
Journal of Proteome Research, 11, 4315-25
Journal of Proteome Research, 11(8), 4315-4325. NLM (Medline)

Item does not contain fulltext To identify response biomarkers for pharmaceutical treatment of multiple sclerosis, we induced experimental autoimmune encephalomyelitis (EAE) in rats and treated symptomatic animals with minocycline. Cerebrospinal flui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f6dca9fc5d69170322d294cb40ec09
https://pure.eur.nl/en/publications/6e3c9bfa-9d69-48b7-8ead-420ff30cbf78

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Simultaneous analysis of plasma and CSF by NMR and hierarchical models fusion

Autor: Paul J. Michiels, Tinka Tuinstra, Joram M. Posma, Sybren S. Wijmenga, Frederic C. Girard, Lutgarde M. C. Buydens, Lionel Blanchet, Theo M. Luider, Agnieszka Smolinska, Amos Attali, Kirsten A.M. Ampt, Marek Doskocz

Publikováno v: Analytical and Bioanalytical Chemistry, 403, 4, pp. 947-959
Analytical and Bioanalytical Chemistry, 403, 947-959
Analytical and Bioanalytical Chemistry, 403(4), 947-59. Springer
Analytical and Bioanalytical Chemistry, 403(4), 947-959. Springer-Verlag
Analytical and Bioanalytical Chemistry

Because cerebrospinal fluid (CSF) is the biofluid which interacts most closely with the central nervous system, it holds promise as a reporter of neurological disease, for example multiple sclerosis (MScl). To characterize the metabolomics profile of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6204719554ec203c4d50a1fb26807e
https://hdl.handle.net/2066/1837662066/103762

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NMR and pattern recognition can distinguish neuroinflammation and peripheral inflammation

Autor: Hans van Aken, Lutgarde M. C. Buydens, Lionel Blanchet, Theo M. Luider, Agnieszka Smolinska, Alain J. van Gool, Sybren S. Wijmenga, Ernst Suidgeest, Amos Attali, Tinka Tuinstra, Kirsten A.M. Ampt

Publikováno v: Journal of Proteome Research, 10, 10, pp. 4428-38
Journal of Proteome Research, 10(10), 4428-4438. American Chemical Society
Journal of Proteome Research, 10, 10, pp. 4428-4438
Journal of Proteome Research, 10(10), 4428-38. American Chemical Society
Journal of Proteome Research, 10, 4428-4438
Journal of Proteome Research, 10, 4428-38

Multiple Sclerosis (MScl) is a neurodegenerative disease of the CNS, associated with chronic neuroinflammation. Cerebrospinal fluid (CSF), being in closest interaction with CNS, was used to profile neuroinflammation to discover disease-specific marke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121cc4288d0cc7b1fcedf101fd0d78fc
https://pubmed.ncbi.nlm.nih.gov/21806074

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Fusion of metabolomics and proteomics data for biomarkers discovery: Case study on the experimental autoimmune encephalomyelitis

Autor: Theo M. Luider, Hans van Aken, Kirsten A.M. Ampt, Marcel P. Stoop, Tinka Tuinstra, Lionel Blanchet, Amos Attali, Agnieszka Smolinska, Ernst Suidgeest, Lutgarde M. C. Buydens, Sybren S. Wijmenga

Publikováno v: BMC Bioinformatics, Vol 12, Iss 1, p 254 (2011)
BMC Bioinformatics, 12
BMC Bioinformatics, 12. BioMed Central Ltd.
BMC Bioinformatics

Background Analysis of Cerebrospinal Fluid (CSF) samples holds great promise to diagnose neurological pathologies and gain insight into the molecular background of these pathologies. Proteomics and metabolomics methods provide invaluable information

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95ff536a0c5f772b93269c42759b8dd
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/91842

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Cerebral blood volume alterations in the perilesional areas in the rat brain after traumatic brain injury--comparison with behavioral outcome

Autor: Amie L Phinney, Vliet Bernard J Van, Olli Gröhn, Taina-Kaisa Stenius, Juha Yrjänheikki, Taneli Heikkinen, Tinka Tuinstra, Antti Nurmi, Riikka Immonen, Leena Tähtivaara, Jukka Puoliväli

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 30(7)

In the traumatic brain injury (TBI) the initial impact causes both primary injury, and launches secondary injury cascades. One consequence, and a factor that may contribute to these secondary changes and functional outcome, is altered hemodynamics. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225f74852b85b0e21c0ae6743628df84
https://pubmed.ncbi.nlm.nih.gov/20145657

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