Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Tingting Gan"'
Autor:
Jinchun Wu, Yang Liu, Liqiong Ou, Tingting Gan, Zhengrong Zhangding, Shaopeng Yuan, Xinyi Liu, Mengzhu Liu, Jiasheng Li, Jianhang Yin, Changchang Xin, Ye Tian, Jiazhi Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Mitochondria serve as the cellular powerhouse, and their distinct DNA makes them a prospective target for gene editing to treat genetic disorders. However, the impact of genome editing on mitochondrial DNA (mtDNA) stability remains a mystery
Externí odkaz:
https://doaj.org/article/381b32eb86f24fcf9a522190b64ea5c1
Autor:
Hengxu Mao, Yaoyun Kuang, Du Feng, Xiang Chen, Lin Lu, Wencheng Xia, Tingting Gan, Weimeng Huang, Wenyuan Guo, Hancun Yi, Yirong Yang, Zhuohua Wu, Wei Dai, Hui Sun, Jieyuan Wu, Rui Zhang, Shenqing Zhang, Xiuli Lin, Yuxuan Yong, Xinling Yang, Hongyan Li, Wenjun Wu, Xiaoyun Huang, Zhaoxiang Bian, Hoi Leong Xavier Wong, Xin-Lu Wang, Michael Poppell, Yi Ren, Cong Liu, Wen-Quan Zou, Shengdi Chen, Ping-Yi Xu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-16 (2024)
Abstract Background Seed amplification assays (SAA) enable the amplification of pathological misfolded proteins, including α-synuclein (αSyn), in both tissue homogenates and body fluids of Parkinson’s disease (PD) patients. SAA involves repeated
Externí odkaz:
https://doaj.org/article/d23c5a987e634c22a6f7e6300ff16365
Autor:
Yaoyun Kuang, Hengxu Mao, Tingting Gan, Wenyuan Guo, Wei Dai, Weimeng Huang, Zhuohua Wu, Hongyan Li, Xiaoyun Huang, Xinling Yang, Ping-Yi Xu
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The seeding amplification assay (SAA) has recently emerged as a valuable tool for detecting α-synuclein (αSyn) aggregates in various clinically accessible biospecimens. Despite its efficiency and specificity, optimal tissue-specific condit
Externí odkaz:
https://doaj.org/article/075d674c1c034a1086cf9f207916014a
Autor:
Gaofang YIN, Nanjing ZHAO, Ming DONG, Mingjun MA, Tingting GAN, Zhisong QIN, Xiang WANG, Peng HUANG, Xiang HU
Publikováno v:
水下无人系统学报, Vol 31, Iss 4, Pp 633-639 (2023)
Marine gross primary productivity(GPP) constitutes a fundamental element of the biological matter cycle and energy flow within the marine ecosystem, serving as a key indicator for assessing the sate of marine ecological environment. Traditional metho
Externí odkaz:
https://doaj.org/article/3f55c610835440b0823bcba1c6fb52ce
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract Introduction To investigate the protective effect of sevoflurane preconditioning on renal ischemia‐reperfusion injury (renalischemiareperfusionmodel, RIRI) and its related mechanism. Methods Eighty healthy adult male SD rats were randomly
Externí odkaz:
https://doaj.org/article/c661f8fb4c4543719c6ab2554d2697df
Autor:
Yang Liu, Chen Ai, Tingting Gan, Jinchun Wu, Yongpeng Jiang, Xuhao Liu, Rusen Lu, Ning Gao, Qing Li, Xiong Ji, Jiazhi Hu
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background Early DNA replication occurs within actively transcribed chromatin compartments in mammalian cells, raising the immediate question of how early DNA replication coordinates with transcription to avoid collisions and DNA damage. Res
Externí odkaz:
https://doaj.org/article/aaadb8da280347eba3f0d8eb1e4aa311
Publikováno v:
Toxics, Vol 11, Iss 5, p 468 (2023)
Heavy metals as toxic pollutants have important impacts on the photosynthesis of microalgae, thus seriously threatening the normal material circulation and energy flow of the aquatic ecosystem. In order to rapidly and sensitively detect the toxicity
Externí odkaz:
https://doaj.org/article/db3125fa10ec43e89eae59c055412900
Transdermal iontophoresis delivery system for terazosin hydrochloride: an in vitro and in vivo study
Autor:
Changzhao Jiang, Xiumei Jiang, Xiumin Wang, Jiaxu Shen, Mengjie Zhang, Leilei Jiang, Rui Ma, Tingting Gan, Yingbiao Gong, Jincui Ye, Wenyan Gao
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 454-462 (2021)
This study aimed to construct a transdermal iontophoresis delivery system for terazosin hydrochloride (IDDS-TEH), which included a positive and negative electrode hydrogel prescription. Intact guinea pig skin was used as a model for the skin barrier
Externí odkaz:
https://doaj.org/article/98a3da4c2f9a44de9a0a1d18f51fb93e
Autor:
Mengyuan Gu, Gaofang Yin, Tingting Gan, Nanjing Zhao, Peilong Qi, Min Chen, Zhichao Ding, Renqing Jia, Jinjing Liu, Mingjun Ma, Ruifang Yang, Li Fang, Wenqing Liu
Publikováno v:
Ecological Indicators, Vol 136, Iss , Pp 108651- (2022)
Pollutants in water seriously threaten the health of human beings and will lead to potential ecological risks to the aquatic environment. Researchers use many chemical, physiological and morphological methods to detect the comprehensive toxicity in w
Externí odkaz:
https://doaj.org/article/70e2aba3520e4e14bad017850eb473fb
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101088- (2022)
Summary: The repair products of double-stranded DNA breaks (DSBs) are crucial for investigating the mechanism underlying DNA damage repair as well as evaluating the safety and efficiency of gene-editing; however, a comprehensively quantitative assay
Externí odkaz:
https://doaj.org/article/c57c8b5a1ab944baacb0de27e8451b74