Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Tingmei, Chen"'
Autor:
Yu Wei, Dian Zhang, He Shi, Husun Qian, Hongling Chen, Qian Zeng, Fangfang Jin, Yan Ye, Zuli Ou, Minkang Guo, Bianqin Guo, Tingmei Chen
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101041- (2024)
Pyruvate dehydrogenase kinase 1 (PDK1) phosphorylates the pyruvate dehydrogenase complex, which inhibits its activity. Inhibiting pyruvate dehydrogenase complex inhibits the tricarboxylic acid cycle and the reprogramming of tumor cell metabolism to g
Externí odkaz:
https://doaj.org/article/50920ea8a3fb4725b15b4adbeb683a89
Autor:
Qingyu Liao, Ruiming Zhang, Zuli Ou, Yan Ye, Qian Zeng, Yange Wang, Anqi Wang, Tingmei Chen, Chengsen Chai, Bianqin Guo
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200762- (2024)
Circulating tumor cells (CTCs) are the seeds of distant metastases of malignant tumors and are associated with malignancy and risk of metastasis. However, tumor cells undergo epithelial-mesenchymal transition (EMT) during metastasis, leading to the e
Externí odkaz:
https://doaj.org/article/526a37691e4a43f68cfd4d31bd31f899
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/ee338860fd10430a958559bc1a3c15a8
Autor:
Weiqian Jiang, Yu Chen, Mingjie Sun, Xiao Huang, Hongrui Zhang, Zheng Fu, Jingjiang Wang, Shichun Zhang, Chengjie Lian, Boyu Tang, Dulei Xiang, Yange Wang, Yulu Zhang, Changchun Jian, Chaohua Yang, Jun Zhang, Dian Zhang, Tingmei Chen, Jian Zhang
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112969- (2023)
Summary: The differentiation fate of bone marrow mesenchymal stem cells (BMSCs) affects the progression of steroid-induced osteonecrosis of the femoral head (SONFH). We find that lncRNA DGCR5 encodes a 102-amino acid polypeptide, RIP (Rac1 inactivate
Externí odkaz:
https://doaj.org/article/70eb3694c6e44e5b9c26f4c51f25a39f
Autor:
Renjie Yuan, Yulu Zhang, Yange Wang, Hongling Chen, Ruiming Zhang, Zhiyuan Hu, Chengsen Chai, Tingmei Chen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundGlucosamine 6-phosphate N-acetyltransferase (GNPNAT1) is a crucial enzyme involving hexosamine biosynthesis pathway and is upregulated in breast cancer (BRCA). However, its biological function and mechanism on patients in BRCA have not been
Externí odkaz:
https://doaj.org/article/d2e537cf1f51413e9c20f942a1d02a8a
Autor:
Husun Qian, Ting Zhou, Yixin Fu, Minkang Guo, Wu Yang, Dian Zhang, Wenli Fang, Mengli Yao, He Shi, Chengsen Chai, Wei Cheng, Shijia Ding, Tingmei Chen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 763-773 (2022)
There is increasing interest in depleting or repolarizing tumor-associated macrophages (TAMs) to generate a proinflammatory effect. However, TAMs usually display an immunosuppressive M2-like phenotype in the tumor microenvironment. Apparently, develo
Externí odkaz:
https://doaj.org/article/1064384c6c2a43e7b42fd44335118f83
Autor:
Wu Yang, Weiwen Zhu, Yunfei Yang, Minkang Guo, Husun Qian, Weiqian Jiang, Yu Chen, Chengjie Lian, Zijie Xu, Haobo Bai, Tingmei Chen, Jian Zhang
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Nontraumatic osteonecrosis of the femoral head (NONFH) is a common, progressive, and refractory orthopaedic disease. Decreased osteogenesis and angiogenesis are considered the main factors in the pathogenesis of NONFH. We aimed to
Externí odkaz:
https://doaj.org/article/5f77d06413984a41a8f57e9ef4ff98fc
Autor:
Wenjun Zhang, Chenyu Xu, Yanjing Rui, Jie Chen, Tingmei Chen, Yimin Dai, Biyun Xu, Yali Hu, Junhao Chen, Yi-Hua Zhou
Publikováno v:
Journal of Virus Eradication, Vol 8, Iss 2, Pp 100076- (2022)
Background: Vertical mother-to-child transmission (MTCT) of the hepatitis B virus (HBV) remains an important issue. Timely administration of hepatitis B immunoglobulin (HBIG) and of the HBV vaccine is effective in preventing MTCT in infants born to H
Externí odkaz:
https://doaj.org/article/d1a664d0c3ac4b43aafd7b23668a0128
Autor:
Wenli Fang, Ting Zhou, He Shi, Mengli Yao, Dian Zhang, Husun Qian, Qian Zeng, Yange Wang, Fangfang Jin, Chengsen Chai, Tingmei Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-11 (2021)
Abstract Background Progranulin (PGRN), as a multifunctional growth factor, is overexpressed in multiple tumors, but the role of PGRN on tumor immunity is still unclear. Here, we studied the effect of PGRN on breast cancer tumor immunity and its poss
Externí odkaz:
https://doaj.org/article/1f3b7095807644b78563ed3fafea797a
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer (BCa) is the most common malignancy in women and claudin-low breast cancer (CL-BCa) is a newly identified BCa subtype characterized by low expression of claudin 3&4&7. However, the hub genes associated with the recruitment of immune cel
Externí odkaz:
https://doaj.org/article/59083d24b7d940829959edfb9bff737f