Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tinglu Ning"'
Autor:
Yaoyu Zou, Peng Lu, Juan Shi, Wen Liu, Minglan Yang, Shaoqian Zhao, Na Chen, Maopei Chen, Yingkai Sun, Aibo Gao, Qingbo Chen, Zhiguo Zhang, Qinyun Ma, Tinglu Ning, Xiayang Ying, Jiabin Jin, Xiaxing Deng, Baiyong Shen, Yifei Zhang, Bo Yuan, Sophie Kauderer, Simin Liu, Jie Hong, Ruixin Liu, Guang Ning, Weiqing Wang, Weiqiong Gu, Jiqiu Wang
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 64-75 (2017)
Background: IRX3 was recently reported as the effector of the FTO variants. We aimed to test IRX3's roles in the browning program and to evaluate the association between the genetic variants in IRX3 and human obesity. Methods: IRX3 expression was exa
Externí odkaz:
https://doaj.org/article/4e0d6cc5871d49eabcf6895a1213e773
Autor:
Philipp E. Scherer, Aimin Li, Hu Zhao, Jiayi Tan, Lei Jiang, Mengle Shao, Xiwei Wu, Qiong A. Wang, Marcia M. Miller, Brian Armstrong, Wenting Dai, Yong Liu, Yi Zhu, Janice M. Huss, Min Jee Jang, Viviana Gradinaru, Zhuo Li, Leonard Medrano, Anying Song, Tinglu Ning
Publikováno v:
Journal of Clinical Investigation. 130:247-257
Brown adipose tissue (BAT), as the main site of adaptive thermogenesis, exerts beneficial metabolic effects on obesity and insulin resistance. BAT has been previously assumed to contain a homogeneous population of brown adipocytes. Utilizing multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c4c05a1d5ef82f5299ecef8b9f8086
https://doi.org/10.1172/jci129167
https://doi.org/10.1172/jci129167
Publikováno v:
EMBO Reports
The cultured brown adipocytes can oxidize glucose in vitro, but it is still not fully clear whether brown adipose tissue (BAT) could completely oxidize glucose in vivo. Although positron emission tomography (PET) with 18F‐fluorodeoxyglucose (18F‐
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5f63525041df08ccc1e20da06bf010
https://doi.org/10.15252/embr.202050085
https://doi.org/10.15252/embr.202050085
Autor:
Aibo Gao, Tinglu Ning, Jiabin Jin, Maopei Chen, Juan Shi, Sophie Kauderer, Baiyong Shen, Jiqiu Wang, Weiqing Wang, Minglan Yang, Qingbo Chen, Jie Hong, Yingkai Sun, Guang Ning, Shaoqian Zhao, Wen Liu, Xiaxing Deng, Ruixin Liu, Weiqiong Gu, Bo Yuan, Yaoyu Zou, Zhiguo Zhang, Peng Lu, Qinyun Ma, Xiayang Ying, Yifei Zhang, Simin Liu, Na Chen
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 64-75 (2017)
EBioMedicine
EBioMedicine
Background IRX3 was recently reported as the effector of the FTO variants. We aimed to test IRX3's roles in the browning program and to evaluate the association between the genetic variants in IRX3 and human obesity. Methods IRX3 expression was exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d535f75bb935fe3c4c7f57be41a0cbc
https://doi.org/10.1016/j.ebiom.2017.09.010
https://doi.org/10.1016/j.ebiom.2017.09.010
Autor:
Guang Ning, Juan Shi, Maopei Chen, Jie Hong, Ruixin Liu, Jiqiu Wang, Minglan Yang, Shaoqian Zhao, Qianqian Lu, Yaoyu Zou, Qinyun Ma, Yingkai Sun, Wen Liu, Tinglu Ning
Publikováno v:
Endocrine. 56:366-378
DGAT2 is the critical catalyzing enzyme for triglyceride biosynthesis, and excess triglyceride accumulation in fat tissues is a fundamental process for obesity. Mutations in DGAT2 or other genes interacting with DGAT2 associated with adiposity have n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4a3693029fefb3733feea95dc0d4fe
https://doi.org/10.1007/s12020-017-1261-1
https://doi.org/10.1007/s12020-017-1261-1
Autor:
Shaoqian Zhao, Yufang Bi, Lu Qi, Weiqing Wang, Min Xu, Tinglu Ning, Min Cao, Rui Wang, Shenghan Lai, Kei Hang K. Chan, Simin Liu, Wen Liu, Maopei Chen, Shumin Duan, Lin Miao, Bao-Liang Song, Weiqiong Gu, Hao-Yan Chen, Huiwen Zhang, Wanyu Li, Zhengqing Qiu, Yingkai Sun, Xianbo Zuo, Jie Hong, Guang Ning, Yaoyu Zou, Hui Xiong, Ruixin Liu, Juan Shi, Yu Xu, Yifei Zhang, Bin Cui, Qinyun Ma, Minglan Yang, Tiange Wang, Jiqiu Wang, Cuijie Wei
Publikováno v:
Diabetes. 66:935-947
Some Shanghai Clinical Center f a role of Niemann-Pick type C1 (NPC1) for obesity traits. However, whether the loss-of-function mutations in NPC1 cause adiposity in humans remains unknown. We recruited 25 probands with rare autosomal-recessive Nieman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::729963796d805d72bde6a7e06ab650b2
https://doi.org/10.2337/db16-0877
https://doi.org/10.2337/db16-0877
Autor:
Yufang Bi, Bin Cui, Sophie Kauderer, Jie Hong, Guang Ning, Tinglu Ning, Ruixin Liu, Lin Ding, Jiqiu Wang, Juan Shi, Simin Liu, Yaoyu Zou, Ya Huang, Min Xu, Maopei Chen
Publikováno v:
Obesity. 25:252-260
OBJECTIVE To determine the relationship of the gain-of-function variant A750T in leucine-rich repeat containing G protein-coupled receptor 4 (LGR4) with central obesity and related metabolic phenotypes. METHODS The LGR4 A750T (c.2248 G > A) variant w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a65a230b17df94057e21fd9fe9b95490
https://doi.org/10.1002/oby.21704
https://doi.org/10.1002/oby.21704
Autor:
Qiong A. Wang, Tinglu Ning
Publikováno v:
Reference Module in Biomedical Sciences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54a7afffac753f7f018ec0fb7c702c73
https://doi.org/10.1016/b978-0-12-801238-3.65508-3
https://doi.org/10.1016/b978-0-12-801238-3.65508-3
Autor:
Shaoqian Zhao, Maopei Chen, Ruixin Liu, Tinglu Ning, Jie Hong, Zhiguo Zhang, Qinyun Ma, Yaoyu Zou, Yingying Ke, Wen Liu, Guang Ning, Juan Shi, Jiqiu Wang, Yingkai Sun
Publikováno v:
Biochemical and Biophysical Research Communications. 464:396-400
Leucine-rich repeat-containing G protein-coupled receptor 4 ( Lgr4 ) is a newfound obese-associated gene. Previous study reveals that heterozygous mutation of Lgr4 correlates with decreased body weight in human. In our recent study, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd83510ebc0b1b10fcb02bec235c5bc
https://doi.org/10.1016/j.bbrc.2015.06.066
https://doi.org/10.1016/j.bbrc.2015.06.066
Autor:
Yaoyu, Zou, Tinglu, Ning, Juan, Shi, Maopei, Chen, Lin, Ding, Ya, Huang, Sophie, Kauderer, Min, Xu, Bin, Cui, Yufang, Bi, Simin, Liu, Jie, Hong, Ruixin, Liu, Guang, Ning, Jiqiu, Wang
Publikováno v:
Obesity (Silver Spring, Md.). 25(1)
To determine the relationship of the gain-of-function variant A750T in leucine-rich repeat containing G protein-coupled receptor 4 (LGR4) with central obesity and related metabolic phenotypes.The LGR4 A750T (c.2248 G A) variant was detected by Sanger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b40942d9c09d75e63891f1dbafd3e24
https://pubmed.ncbi.nlm.nih.gov/27925416
https://pubmed.ncbi.nlm.nih.gov/27925416