Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tinglin Pu"'
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-17 (2019)
Abstract Background Abnormal aggregation of brain α-synuclein is a central step in the pathogenesis of Parkinson’s disease (PD), thus, it is reliable to promote the clearance of α-synuclein to prevent and treat PD. Recent studies have revealed an
Externí odkaz:
https://doaj.org/article/d74540ceb92e442a98186dcef186084e
Autor:
Humberto Mestre, Lauren M Hablitz, Anna LR Xavier, Weixi Feng, Wenyan Zou, Tinglin Pu, Hiromu Monai, Giridhar Murlidharan, Ruth M Castellanos Rivera, Matthew J Simon, Martin M Pike, Virginia Plá, Ting Du, Benjamin T Kress, Xiaowen Wang, Benjamin A Plog, Alexander S Thrane, Iben Lundgaard, Yoichiro Abe, Masato Yasui, John H Thomas, Ming Xiao, Hajime Hirase, Aravind Asokan, Jeffrey J Iliff, Maiken Nedergaard
Publikováno v:
eLife, Vol 7 (2018)
The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-β. Influx of cerebrospinal fluid (CSF) depends upon the expression and perivascular localization of the astroglial water channel aquap
Externí odkaz:
https://doaj.org/article/9fe3ab146a0849b2a74eb8c9bba7a959
Publikováno v:
Brain, Behavior, and Immunity. 64:232-243
Early social isolation (SI) produces a variety of emotional, behavioral and cognitive abnormalities. Conversely, environmental enrichment (EE), a complicated social and physical construct, offers beneficial effects on brain plasticity and development
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-17 (2019)
Translational Neurodegeneration
Translational Neurodegeneration
Background Abnormal aggregation of brain α-synuclein is a central step in the pathogenesis of Parkinson’s disease (PD), thus, it is reliable to promote the clearance of α-synuclein to prevent and treat PD. Recent studies have revealed an essentia
Autor:
Matthew J. Simon, Ming Xiao, Virginia Plá, Wenyan Zou, Humberto Mestre, Tinglin Pu, Alexander S. Thrane, Xiaowen Wang, Ruth M. Castellanos Rivera, Weixi Feng, Masato Yasui, Hiromu Monai, Anna Lr Xavier, Hajime Hirase, Jeffrey J. Iliff, Benjamin A. Plog, Giridhar Murlidharan, Benjamin T. Kress, Yoichiro Abe, John H. Thomas, Ting Du, Lauren M. Hablitz, Iben Lundgaard, Aravind Asokan, Martin M. Pike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c3d0013044dcfa97b44e2c5cf927e1b
https://doi.org/10.7554/elife.40070.022
https://doi.org/10.7554/elife.40070.022
Publikováno v:
Experimental Neurobiology
Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular event that often is followed by permanent brain impairments. It is necessary to explore the pathogenesis of secondary pathological damages in order to find effective interventions for imp
Autor:
Wenyan Zou, Benjamin A. Plog, Ruth M. Castellanos Rivera, Benjamin T. Kress, Iben Lundgaard, Tinglin Pu, Yoichiro Abe, Aravind Asokan, Xiaowen Wang, Anna L.R. Xavier, Matthew J. Simon, Masato Yasui, Ting Du, Humberto Mestre, Hajime Hirase, Alexander S. Thrane, Hiromu Monai, Giridhar Murlidharan, Lauren M. Hablitz, Ming Xiao, Virginia Plá, Martin M. Pike, John H. Thomas, Weixi Feng, Jeffrey J. Iliff
Publikováno v:
eLife
eLife, Vol 7 (2018)
Mestre, H, Hablitz, L M, Xavier, A L R, Feng, W, Zou, W, Pu, T, Monai, H, Murlidharan, G, Rivera, R M C, Simon, M J, Pike, M M, Pla, V, Du, T, Kress, B T, Wang, X, Plog, B A, Thrane, A S, Lundgaard, I, Abe, Y, Yasui, M, Thomas, J H, Xiao, M, Hirase, H, Asokan, A, Iliff, J J & Nedergaard, M 2018, ' Aquaporin-4-dependent glymphatic solute transport in the rodent brain ', eLife, vol. 7, :e40070 . https://doi.org/10.7554/eLife.40070
eLife, Vol 7 (2018)
Mestre, H, Hablitz, L M, Xavier, A L R, Feng, W, Zou, W, Pu, T, Monai, H, Murlidharan, G, Rivera, R M C, Simon, M J, Pike, M M, Pla, V, Du, T, Kress, B T, Wang, X, Plog, B A, Thrane, A S, Lundgaard, I, Abe, Y, Yasui, M, Thomas, J H, Xiao, M, Hirase, H, Asokan, A, Iliff, J J & Nedergaard, M 2018, ' Aquaporin-4-dependent glymphatic solute transport in the rodent brain ', eLife, vol. 7, :e40070 . https://doi.org/10.7554/eLife.40070
The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-β. Influx of cerebrospinal fluid (CSF) depends upon the expression and perivascular localization of the astroglial water channel aquap
Publikováno v:
International Journal of Neuropsychopharmacology
Background Social isolation in the elderly is one of the principal health risks in an aging society. Physical environmental enrichment is shown to improve sensory, cognitive, and motor functions, but it is unknown whether environmental enrichment can
Publikováno v:
Medical hypotheses. 119
Currently, there are no effective drug therapies for Alzheimer's disease (AD). Thus, exploring new non-pharmacological strategies, including the neuroprotective mechanisms of aerobic exercise, to enhance therapeutic treatment of AD are essential. Pre
Autor:
Humberto Mestre, Benjamin T. Kress, Wenyan Zou, Tinglin Pu, Giridhar Murlidharan, Ruth M. Castellanos Rivera, Matthew J. Simon, Martin M. Pike, Benjamin A Plog, Anna L. R. Xavier, Alexander S. Thrane, Iben Lundgaard, John H. Thomas, Ming Xiao, Aravind Asokan, Jeffrey J. Miff, Maiken Nedergaard
The glymphatic system is a brain-wide metabolite clearance pathway, impairment of which in post-traumatic and ischemic brain or healthy aging is proposed to contribute to intracerebral accumulation of amyloid-β and tau proteins. Glymphatic perivascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404e1d0765c3842cd21c5403b87bc170