Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tinghan Zhao"'
Publikováno v:
Cells, Vol 13, Iss 9, p 781 (2024)
mTOR is a central regulator of cell growth and metabolism in response to mitogenic and nutrient signals. Notably, mTOR is not only found in the cytoplasm but also in the nucleus. This review highlights direct involvement of nuclear mTOR in regulating
Externí odkaz:
https://doaj.org/article/286c1943e93444e3b0aac12debb6cdea
Autor:
Tinghan Zhao, Mehrun Nahar Uddin, Zhaoxiong Wan, Yuanwei Zhang, Shupei Yu, Karthik Sambath, Kevin D. Belfield
Publikováno v:
Chemistry – A European Journal. 27:247-251
Chemoresistance is one of the major challenges for cancer treatment, more recently ascribed to defective mitochondrial outer membrane permeabilization (MOMP), significantly diminishing chemotherapeutic agent-induced apoptosis. A boron-dipyrromethene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcafde0438c8e30c549b716163cf1d3
https://doi.org/10.1002/chem.202004278
https://doi.org/10.1002/chem.202004278
Autor:
Jaume Veciana, Cristina Sissa, Kevin D. Belfield, Nora Ventosa, Judit Morla-Folch, Anna Painelli, Mariana Köber, Mehrun Nahar Uddin, Antonio Ardizzone, Guillem Vargas-Nadal, Tinghan Zhao, Siarhei Kurhuzenkau
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Fluorescent organic nanoparticles (FONs) are emerging as an attractive alternative to the well-established fluorescent inorganic nanoparticles or small organic dyes. Their proper design allows one to obtain biocompatible probes with superior brightne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48dab1dd9a93ce677e8285ff7a3c865
http://hdl.handle.net/10261/211681
http://hdl.handle.net/10261/211681
Publikováno v:
Chemical communications (Cambridge, England). 55(94)
A new class of BODIPY-based oxime ester photo-uncaging group was designed to release carboxylic acids. The mechanism and kinetics of the photo-uncaging procedure were studied. Further, we constructed a photo-uncaging drug delivery system to release v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fbe20cf329c435ccbae48edb2321ad
https://pubmed.ncbi.nlm.nih.gov/31701102
https://pubmed.ncbi.nlm.nih.gov/31701102
Autor:
Tinghan Zhao, Yuanwei Zhang, Masanobu Komatsu, Junko Sawada, Xiangshan Liu, Xinglei Liu, Sweety Singh, Kevin D. Belfield
Publikováno v:
Bioconjugate chemistry. 30(9)
Mitochondria are essential targets for treatment of diseases with mitochondrial disorders such as diabetes, cancer, and cardiovascular and neurodegenerative diseases. Mitochondria penetrating peptides (MPPs) are composed of cationic and hydrophobic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1c4bfd1d65ef8fe4f9e71d1dfec8a1
https://pubmed.ncbi.nlm.nih.gov/31433175
https://pubmed.ncbi.nlm.nih.gov/31433175
Publikováno v:
Scopus-Elsevier
A novel mitochondria penetrating peptide (MPP) that can permeate the mitochondrial membrane for long-term tracking of mitochondria is reported. In-vitro studies indicate persistence of the MPP probe, low cytotoxicity, and high bio-compatibility.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de61a7b2ecc238b129dedaef9dc593cf
https://doi.org/10.1364/omp.2019.om3d.5
https://doi.org/10.1364/omp.2019.om3d.5