Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Tingbo Ding"'
Autor:
Shuhua He, Xiang Gu, Jintong Yang, Fei Xu, Jiachun Hu, Wei Wang, Yiheng Huang, Bin Lou, Tingbo Ding, Lu Zhou, Deyong Ye, Ker Yu, Jibin Dong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Tumor-associated macrophages (TAMs) are one of the most abundant immune cells in the pancreatic cancer stroma and are related to the poor prognosis of pancreatic ductal adenocarcinoma (PDAC) patients. Therefore, targeting tumor-associated
Externí odkaz:
https://doaj.org/article/f6326105ed07431dafd7f7c6b77fed06
Autor:
Xinming Du, Jiachun Hu, Qing Zhang, Qi Liu, Xinxin Xiang, Jibin Dong, Bin Lou, Shuhua He, Xiang Gu, Yu Cao, Yingxia Li, Tingbo Ding
Publikováno v:
FEBS Open Bio, Vol 9, Iss 10, Pp 1734-1743 (2019)
Lysophosphatidylcholine acyltransferase 3 (LPCAT3) is an important enzyme in phospholipid remodeling, a process that influences the biophysical properties of cell membranes and thus cell function. Multiple lines of evidence suggest that LPCAT3 is inv
Externí odkaz:
https://doaj.org/article/8d9cce87883a426c923752a9ac468e01
Publikováno v:
Marine Drugs, Vol 18, Iss 7, p 344 (2020)
Given our previous finding that fluorination at the C18 position of largazole showed reasonably good tolerance towards inhibitory activity and selectivity of histone deacetylases (HDACs), further modification on the valine residue in the fluoro-larga
Externí odkaz:
https://doaj.org/article/384535cf2d2542babd63c09da14f7b0c
Autor:
Tingbo Ding, Inamul Kabir, Yue Li, Caixia Lou, Amirfarbod Yazdanyar, Jiachen Xu, Jibin Dong, Hongwen Zhou, Taesik Park, Mohamed Boutjdir, Zhiqiang Li, Xian-Cheng Jiang
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 3, Pp 537-545 (2015)
Sphingomyelin synthase-related protein (SMSr) synthesizes the sphingomyelin analog ceramide phosphoethanolamine (CPE) in cells. Previous cell studies indicated that SMSr is involved in ceramide homeostasis and is crucial for cell function. To further
Externí odkaz:
https://doaj.org/article/2ce1f8479e20443192e139b30a0c048c
Autor:
Bin Lou, Jibin Dong, Yali Li, Tingbo Ding, Tingting Bi, Yue Li, Xiaodong Deng, Deyong Ye, Xian-Cheng Jiang
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102641 (2014)
Sphingomyelin synthase (SMS) plays an important role in plasma atherogenic lipoprotein metabolism, inflammation, and the development of atherosclerosis. To understand whether the impaired apoB secretion and inflammation response is a direct result fr
Externí odkaz:
https://doaj.org/article/8f149e6657d84aa18e83c37317234c00
Publikováno v:
Acta Biochimica et Biophysica Sinica.
Phosphatidylcholines (PCs) are major phospholipids in the mammalian cell membrane. Structural remodeling of PCs is associated with many biological processes. Lysophosphatidylcholine acyltransferase 3 (Lpcat3), which catalyzes the incorporation of pol
Publikováno v:
Acta Biochimica et Biophysica Sinica; Jan2023, Vol. 55 Issue 1, p117-130, 14p
Autor:
Qi Xiangyu, Huiti Li, Tingbo Ding, Jibin Dong, Chen Yan, Min Wei, Shuang Hu, Yang Cao, Nengneng Cheng, Li Yali, Mo Mingguang, Bin Lou, Deyong Ye, Yong Chu, Xiaoxia Li, Xian-Cheng Jiang, Taomin Huang, Lu Zhou
Publikováno v:
European Journal of Medicinal Chemistry. 163:864-882
The sphingomyelin synthase 2 (SMS2) is a potential target for pharmacological intervention in atherosclerosis. However, so far, few selective SMS2 inhibitors and their pharmacological activities were reported. In this study, a class of 2-benzyloxyben
Autor:
Xinxin Xiang, Jia-chun Hu, Qi Liu, Xinming Du, Jibin Dong, Xiang Gu, Yu Cao, Qing Zhang, Tingbo Ding, Yingxia Li, Shu-hua He, Bin Lou
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 9, Iss 10, Pp 1734-1743 (2019)
FEBS Open Bio, Vol 9, Iss 10, Pp 1734-1743 (2019)
Lysophosphatidylcholine acyltransferase 3 (LPCAT3) is an important enzyme in phospholipid remodeling, a process that influences the biophysical properties of cell membranes and thus cell function. Multiple lines of evidence suggest that LPCAT3 is inv
Publikováno v:
Marine Drugs; Volume 18; Issue 7; Pages: 344
Marine Drugs, Vol 18, Iss 344, p 344 (2020)
Marine Drugs
Marine Drugs, Vol 18, Iss 344, p 344 (2020)
Marine Drugs
Given our previous finding that fluorination at the C18 position of largazole showed reasonably good tolerance towards inhibitory activity and selectivity of histone deacetylases (HDACs), further modification on the valine residue in the fluoro-larga