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pro vyhledávání: '"Ting-Yu Song"'
Autor:
Jia-Wen Guo, Ran Li, Yun-Dong Fu, Zi-Tong Chen, Hong-Min Liu, Li-Hua Huang, Ting-Yu Song, Ming-Jie Huang, Wen-Yu Xu, Ya-Zhen You
Publikováno v:
Bioorganicmedicinal chemistry letters. 41
Tranylcypromine (TCP)-based structural modifications lead to the discovery of new LSD1 inhibitors, of which compounds 26b and 29b effectively inhibit LSD1 with the IC50 values of 17 and 11 nM, respectively and also show good selectivity over MAO-B. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb185f8e23b61e8b8e2544d788efeae1
https://pubmed.ncbi.nlm.nih.gov/33775841
https://pubmed.ncbi.nlm.nih.gov/33775841
