Výsledky vyhledávání - "Ting-Yu Ding"

Akademický článek

Involvement of Histone Lysine Crotonylation in the Regulation of Nerve-Injury-Induced Neuropathic Pain

Autor: Yu Zou, Xue-Hui Bai, Ling-Chi Kong, Fei-Fei Xu, Ting-Yu Ding, Peng-Fei Zhang, Fu-Lu Dong, Yue-Juan Ling, Bao-Chun Jiang

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Histone lysine crotonylation (KCR), a novel epigenetic modification, is important in regulating a broad spectrum of biological processes and various diseases. However, whether KCR is involved in neuropathic pain remains to be elucidated. We found KCR

Externí odkaz: https://doaj.org/article/cbe42e32ee464b3ab887d44c5f824a79

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NFAT1 Orchestrates Spinal Microglial Transcription and Promotes Microglial Proliferation via c-MYC Contributing to Nerve Injury-Induced Neuropathic Pain

Autor: Bao‐Chun Jiang, Ting‐Yu Ding, Chang‐Yun Guo, Xue‐Hui Bai, De‐Li Cao, Xiao‐Bo Wu, Wei‐Lin Sha, Ming Jiang, Long‐Jun Wu, Yong‐Jing Gao

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(27)

Peripheral nerve injury-induced spinal microglial proliferation plays a pivotal role in neuropathic pain. So far, key intracellular druggable molecules involved in this process are not identified. The nuclear factor of activated T-cells (NFAT1) is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7bffd53b42b2b580b09ea3715939b5
https://pubmed.ncbi.nlm.nih.gov/35892263

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Intravenous Administration of Triptonide Attenuates CFA-Induced Pain Hypersensitivity by Inhibiting DRG AKT Signaling Pathway in Mice

Autor: Fu-Lu Dong, Yue-Juan Ling, Yong-Jing Gao, Bao-Chun Jiang, Ting-Yu Ding

Publikováno v: Journal of Pain Research. 13:3195-3206

Background Currently, medical treatment of inflammatory pain is limited by a lack of safe and effective therapies. Triptonide (TPN), a major component of Tripterygium wilfordii Hook.f. with low toxicity, has been shown to have good anti-inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ff615bf26d8e8fc9e82f9f5387840af
https://doi.org/10.2147/jpr.s275320

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Intravenous administration of triptonide attenuates CFA-induced pain hypersensitivity through inhibiting AKT signaling pathway in mice

Autor: Yue-Juan Ling, Ting-Yu Ding, Yong-Jing Gao, Bao-Chun Jiang

Background: Triptonide (TPN) is a major component of Tripterygium wilfordii Hook.f., and reportedly has anti-inflammatory and neuroprotective effects. Recent studies have demonstrated that the phosphatidylinositol 3-kinase (PI3K)/AKT pathway plays an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78202ba712e7579d5536119750918720
https://doi.org/10.21203/rs.2.19974/v1

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