Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ting-Li Tang"'
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-10 (2022)
Abstract Ferroptosis, a newly discovered iron-dependent cell death pathway, is characterized by lipid peroxidation and GSH depletion mediated by iron metabolism and is morphologically, biologically and genetically different from other programmed cell
Externí odkaz:
https://doaj.org/article/b26221cd93184cadbafc41cb6cac2324
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Sunitinib is a multi-targeted tyrosine kinase inhibitor with remarkable anticancer activity, while hepatotoxicity is a potentially fatal adverse effect of its administration. The aim of this study was to elucidate the mechanism of hepatotoxicity indu
Externí odkaz:
https://doaj.org/article/b769dea4fbe34f2c8d4f8ac0e4a5d62e
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Considerable attention has been raised on crizotinib- and sunitinib-induced hepatotoxicity, but the underlying mechanisms need further examination. In addition, limited therapeutic strategies exist to reduce the liver damage caused by crizotinib and
Externí odkaz:
https://doaj.org/article/32b7540b592b4686b27c1b9fc379791a