Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ting-Jen Rachel Cheng"'
Autor:
Yu-Ling Tseng, Po-Chao Lu, Chi-Chang Lee, Ruei-Yu He, Yung-An Huang, Yin-Chen Tseng, Ting-Jen Rachel Cheng, Joseph Jen-Tse Huang, Jim-Min Fang
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-21 (2023)
Abstract Background Amyotrophic lateral sclerosis (ALS) associated with TAR DNA-binding protein 43 (TDP-43) aggregation has been considered as a lethal and progressive motor neuron disease. Recent studies have shown that both C-terminal TDP-43 (C-TDP
Externí odkaz:
https://doaj.org/article/461b394b4545469c870b07ecbc2ec3c9
Autor:
Pin-Hsuan Chiu, Wei Huang, Hua-Ting Hsu, Wen-Feng Huang, Ying-Ta Wu, Ting-Jen Rachel Cheng, Jim-Min Fang
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 6, Iss , Pp 100091- (2022)
Targeting the highly conserved E330 … R416 salt bridge involved in nucleoprotein (NP) trimerization is considered a favorable approach to address the problem of drug resistance in influenza therapy. A photoaffinity probe (1) containing aryl and alk
Externí odkaz:
https://doaj.org/article/299923ba6610420fad45f6db3d13136b
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The extracellular human endo-6-O-sulfatases (Sulf-1 and Sulf-2) are responsible for the endolytic cleavage of the 6-sulfate groups from the internal D-glucosamine residues in the highly sulfated subdomains of heparan sulfate proteoglycans. A trisacch
Externí odkaz:
https://doaj.org/article/447721da156947eda5945ee8a364e9fd
Autor:
Sui-Yuan Chang, Kuo-Yen Huang, Tai-Ling Chao, Han-Chieh Kao, Yu-Hao Pang, Lin Lu, Chun-Lun Chiu, Hsin-Chang Huang, Ting-Jen Rachel Cheng, Jim-Min Fang, Pan-Chyr Yang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract A metal nanoparticle composite, namely TPNT1, which contains Au-NP (1 ppm), Ag-NP (5 ppm), ZnO-NP (60 ppm) and ClO2 (42.5 ppm) in aqueous solution was prepared and characterized by spectroscopy, transmission electron microscopy, dynamic ligh
Externí odkaz:
https://doaj.org/article/ec8172096624498282192a2444a374c0
Autor:
Yi-An Ko, Yueh-Hsiang Yu, Yen-Fei Wu, Yung-Chieh Tseng, Chia-Lin Chen, King-Siang Goh, Hsin-Yu Liao, Ting-Hua Chen, Ting-Jen Rachel Cheng, An-Suei Yang, Chi-Huey Wong, Che Ma, Kuo-I Lin
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
Hemagglutinin (HA) is the immunodominant protein of the influenza virus. We previously showed that mice injected with a monoglycosylated influenza A HA (HAmg) produced cross-strain-reactive antibodies and were better protected than mice injected with
Externí odkaz:
https://doaj.org/article/74ae43827c054dd89beda4ed1ea0e547
Autor:
Jing Li, Shih-Yi Hsiung, Mu-Rong Kao, Xiaohui Xing, Shu-Chieh Chang, Damao Wang, Pei-Yun Hsieh, Pi-Hui Liang, Zaibiao Zhu, Ting-Jen Rachel Cheng, Jiun-Jie Shie, Jing-Ping Liou, D. Wade Abbott, Sung Won Kwon, Yves S.Y. Hsieh
Publikováno v:
Carbohydrate research. 521
Polygonatum odoratum is a perennial rhizomatous medicinal plant and different plant parts have been used in the treatment of various ailments. Herein, we have investigated the structural compositions of rhizome, leaf, and stem cell walls. We found 30
Autor:
Han-Yi Huang, Hsin-Yu Liao, Xiaorui Chen, Szu-Wen Wang, Cheng-Wei Cheng, Md. Shahed-Al-Mahmud, Yo-Min Liu, Arpita Mohapatra, Ting-Hua Chen, Jennifer M. Lo, Yi-Min Wu, Hsiu-Hua Ma, Yi-Hsuan Chang, Ho-Yang Tsai, Yu-Chi Chou, Yi-Ping Hsueh, Ching-Yen Tsai, Pau-Yi Huang, Sui-Yuan Chang, Tai-Ling Chao, Han-Chieh Kao, Ya-Min Tsai, Yen-Hui Chen, Chung-Yi Wu, Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Kuo-I Lin, Che Ma, Chi-Huey Wong
Publikováno v:
Science translational medicine. 14(639)
A major challenge to end the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to develop a broadly protective vaccine that elicits long-term immunity. As the key immunogen, the viral surface spike (S) protein is freq
Autor:
Yu-Hsin Chen, Wei-An Chen, Ashik A. Sayyad, Ting-Jen Rachel cheng, Chiao-Wen Chen, Wei-Chieh Cheng
Publikováno v:
Asian Journal of Organic Chemistry. 8:2233-2242
Autor:
Hao-Chun, Chuang, Ming-Fang, Liu, Hsin-Yi, Wu, Ying-Ta, Wu, Ting-Jen Rachel, Cheng, Jim-Min, Fang
Publikováno v:
Bioorganic & Medicinal Chemistry. 67:116819
A series of salicylanilide compounds was previously identified as antibacterial agents that inhibit the peptidoglycan formation. To find the exact binding mode, we synthesized a benzophenone-containing salicylanilide compound (1) and used it as a pho
Autor:
Li-Ting, Chiu, Narayana Murthy, Sabbavarapu, Wei-Chen, Lin, Chiao-Yuan, Fan, Chih-Chung, Wu, Ting-Jen Rachel, Cheng, Chi-Huey, Wong, Shang-Cheng, Hung
Publikováno v:
Journal of the American Chemical Society. 142(11)
Human endo