Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Ting Zhuang"'
Autor:
Ting Zhuang, Shuqing Zhang, Dongyi Liu, Zhongbo Li, Xin Li, Jiaoyan Li, Penghe Yang, Chenmiao Zhang, Jiayao Cui, Mingxi Fu, Fangyu Shen, Lei Yuan, Zhao Zhang, Peng Su, Jian Zhu, Huijie Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Breast cancer is the most prevalent cancer in women globally. Over-activated estrogen receptor (ER) α signaling is considered the main factor in luminal breast cancers, which can be effectively managed with selective estrogen rec
Externí odkaz:
https://doaj.org/article/768a7bedac244ef4a0d279eea2a13216
Autor:
Tianshi Wang, Dehai Wang, Yanan Sun, Ting Zhuang, Xin Li, Huijie Yang, Yifeng Zang, Ziping Liu, Penghe Yang, Chenmiao Zhang, Jiayao Cui, Mingxi Fu, Shuqing Zhang, Peng Su, Zhongbo Li, Jian Zhu, Yinlu Ding
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-22 (2023)
Abstract Background The Hippo pathway is crucial in organ size control and tumorigenesis. Dysregulation of the Hippo/YAP axis is commonly observed in gastric cancer, while effective therapeutic targets for the Hippo/YAP axis are lacking. Identificati
Externí odkaz:
https://doaj.org/article/9736990632cd4b10a68758d5b9d7729a
Autor:
Huijie Yang, Min Xue, Peng Su, Yan Zhou, Xin Li, Zhongbo Li, Yan Xia, Chenmiao Zhang, Mingxi Fu, Xiuxia Zheng, Guosheng Luo, Tian Wei, Xinxing Wang, Yinlu Ding, Jian Zhu, Ting Zhuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Highlights 1. RNF31 restrains cancer cell progression in TNBC. 2. RNF31 regulates YAP protein stability via promoting YAP K48-linked poly-ubiquitination. 3. RNF31 represses immune evasion via suppressing YAP/PD-L1 axis in TNBC.
Externí odkaz:
https://doaj.org/article/0099d83b71d34297ae249c7332947240
Autor:
Zhiguo Niu, Jianing Fan, Fengzhe Chen, Huijie Yang, Xin Li, Ting Zhuang, Chunlei Guo, Qi Cao, Jian Zhu, Hui Wang, Qingsong Huang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-11 (2022)
Abstract Breast cancer is the most common malignancy in women on a global scale. It can generally be divided into four main categories, of which estrogen receptor ER-positive breast cancer accounts for most breast cancer cases. RBCK1 protein is an E3
Externí odkaz:
https://doaj.org/article/6eca799ada504c11859640cb9d98f766
Autor:
Zhongbo Li, Peng Su, Yinlu Ding, Honglei Gao, Huijie Yang, Xin Li, Xiao Yang, Yan Xia, Chenmiao Zhang, Mingxi Fu, Dehai Wang, Ye Zhang, Shu Zhuo, Jian Zhu, Ting Zhuang
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Triple negative breast cancer (TNBC) is one of the most lethal breast cancer subtypes. Due to a lack of effective therapeutic targets, chemotherapy is still the main medical treatment for TNBC patients. Thus, it is important and n
Externí odkaz:
https://doaj.org/article/21ace992caea4ac187fbf04fedb51950
Autor:
Dehai Wang, Zhongbo Li, Xin Li, Cheng Yan, Huijie Yang, Ting Zhuang, Xiao Wang, Yifeng Zang, Ziping Liu, Tianshi Wang, Rixia Jiang, Peng Su, Jian Zhu, Yinlu Ding
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-17 (2022)
Highlights 1. DUB1 is an important modulator of Hippo signaling in gastric cancer. 2. DUB1 expression is elevated in human gastric cancer samples and correlates with poor survival in gastric cancer. 3. DUB1 facilitates gastric cancer progression via
Externí odkaz:
https://doaj.org/article/2fdc017c5a9c4d9aaef1fa5cec6b80ce
Autor:
Xu Li, Shu Zhuo, Ting Zhuang, Yong Suk Cho, Guojin Wu, Yuchen Liu, Kun Mu, Kai Zhang, Peng Su, Yingzi Yang, Cheng Cheng Zhang, Jian Zhu, Jin Jiang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Recent studies have reported that oncoprotein YAP can function as tumour suppressor in certain contexts. Here the authors show that inhibition of Hippo signalling or YAP activation blocks ERα transcriptional program and ER + breast cancer growth and
Externí odkaz:
https://doaj.org/article/903d62df88104f45a8c7b8a973802858
Autor:
Ting Zhuang, Beibei Wang, Xiaojing Tan, Le Wu, Xin Li, Zhongbo Li, Yuqing Cai, Rongrong Fan, Xiao Yang, Chenmiao Zhang, Yan Xia, Zhiguo Niu, Bingtian Liu, Qi Cao, Yinlu Ding, Zhipeng Zhou, Qingsong Huang, Huijie Yang
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Breast cancer is the most common cancer in women worldwide. More than 70% of breast cancers are estrogen receptor (ER) alpha positive. Compared with ER alpha-negative breast cancer, which is more aggressive and has a shorter survi
Externí odkaz:
https://doaj.org/article/0fbe5404c420403ca1bdc9e3001d6840
Autor:
Xin Li, Zhiguo Niu, Chen Sun, Shu Zhuo, Huijie Yang, Xiao Yang, Yun Liu, Cheng Yan, Zhongbo Li, Qi Cao, Guimei Ji, Yinlu Ding, Ting Zhuang, Jian Zhu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-11 (2022)
Abstract The tumor suppressor P53 plays critical role in preventing cancer. P53 is rarely mutated and remains functional in luminal-type breast cancer(1). According to current knowledge, wild-type P53 function is tightly controlled by posttranslation
Externí odkaz:
https://doaj.org/article/11eb63a714f44e6b993dbf90a27d9267
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Breast cancer ranks No. 1 in women cancer incidence, while triple negative breast cancer (TNBC) is the most aggressive and the worst prognostic subtype in all breast cancer subtypes. Compared with estrogen receptor alpha positive
Externí odkaz:
https://doaj.org/article/2c7d8dd203804bd1ad55f213ae4dabd1