Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ting Wen Lo"'
Publikováno v:
Biosensors and Bioelectronics: X, Vol 19, Iss , Pp 100490- (2024)
PD1/PD-L1 checkpoint inhibitors are at the forefront of cancer immunotherapies. However, the overall response rate remains only 10–30%. Even among initial responders, drug resistance often occurs, which can lead to prolonged use of a futile therapy
Externí odkaz:
https://doaj.org/article/47a5116c8d0c4bb9a4b71ace27585800
Autor:
Emma Purcell, Sarah Owen, Emily Prantzalos, Abigail Radomski, Nayri Carman, Ting-Wen Lo, Mina Zeinali, Chitra Subramanian, Nithya Ramnath, Sunitha Nagrath
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In non-small cell lung cancer (NSCLC), identifying the presence of sensitizing and resistance epidermal growth factor receptor (EGFR) mutations dictates treatment plans. Extracellular vesicles (EVs) are emerging as abundant, stable potential liquid b
Externí odkaz:
https://doaj.org/article/f88f5036fc264c2a81eb9c63bb5ee78c
Autor:
Ting-wen Lo, Claudia Figueroa-Romero, Junguk Hur, Crystal Pacut, Evan Stoll, Calvin Spring, Rose Lewis, Athul Nair, Stephen A. Goutman, Stacey A. Sakowski, Sunitha Nagrath, Eva L. Feldman
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and molecular observations suggest that ALS pathology originates at a single site and spreads in an organized and prion-like manner, possibly driven by extracellular
Externí odkaz:
https://doaj.org/article/096cc19ce0b6428abc876d39c85f314d
Autor:
Xiaotian Tan, Kathleen C. Day, Xuzhou Li, Luke J. Broses, Wen Xue, Weishu Wu, William Y. Wang, Ting-Wen Lo, Emma Purcell, Sicong Wang, Yun-Lu Sun, Maung Kyaw Khaing Oo, Brendon M. Baker, Sunitha Nagrath, Mark L. Day, Xudong Fan
Publikováno v:
Biosensors and Bioelectronics: X, Vol 8, Iss , Pp 100066- (2021)
The functional membrane proteins on tumor-cell-derived EVs contain a large amount of biomolecular information, and can serve as a comprehensive marker to delineate the molecular nature of cancer. However, due to low secretion rates, it is difficult t
Externí odkaz:
https://doaj.org/article/f0e5c940854b43aa825d015c3ef79244
Autor:
Yoon‐Tae Kang, Zeqi Niu, Thomas Hadlock, Emma Purcell, Ting‐Wen Lo, Mina Zeinali, Sarah Owen, Venkateshwar G. Keshamouni, Rishindra Reddy, Nithya Ramnath, Sunitha Nagrath
Publikováno v:
Advanced Science, Vol 8, Iss 6, Pp n/a-n/a (2021)
Abstract As the recognition between natural killer (NK) cells and cancer cells does not require antigen presentation, NK cells are being actively studied for use in adoptive cell therapies in the rapidly evolving armamentarium of cancer immunotherapy
Externí odkaz:
https://doaj.org/article/1fe86000dcdb48de8238d16d2b30f982
Autor:
Yoon‐Tae Kang, Thomas Hadlock, Ting‐Wen Lo, Emma Purcell, Anusha Mutukuri, Shamileh Fouladdel, Monica De Silva Raguera, Heather Fairbairn, Vasudha Murlidhar, Alison Durham, Scott A. McLean, Sunitha Nagrath
Publikováno v:
Advanced Science, Vol 7, Iss 19, Pp n/a-n/a (2020)
Abstract Melanoma is among the most aggressive cancers, and its rate of incidence continues to grow. Early detection of melanoma has been hampered due to the lack of promising markers for testing. Recent advances in liquid biopsy have proposed noninv
Externí odkaz:
https://doaj.org/article/2478a8956f83442dae965a06016983c9
Autor:
Junguk Hur, Ximena Paez-Colasante, Claudia Figueroa-Romero, Ting-wen Lo, Sami J Barmada, Michelle T Paulsen, Mats Ljungman, Fadhl M Alakwaa, Masha G Savelieff, Stephen A Goutman, Eva L Feldman
Publikováno v:
Human molecular genetics.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Its complex pathogenesis and phenotypic heterogeneity hinder therapeutic development and early diagnosis. Altered RNA metabolism is a recurrent pathophysiologic theme, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c9240be3e04353efa5957c46739da1
https://pubmed.ncbi.nlm.nih.gov/36219176
https://pubmed.ncbi.nlm.nih.gov/36219176
Autor:
Sarah Owen, Janusz Franco-Barraza, Vaibhav Sahai, Theodore S. Lawrence, Sunitha Nagrath, Jiaqi Shi, Edna Cukierman, Anjali Mittal, Mara H. Sherman, Ziwen Zhu, Noah Meurs, Anirban Maitra, Andrew M. Pickering, Olamide Animasahun, Meredith A. Morgan, Abhinav Achreja, Deepak Nagrath, Ting Wen Lo, Valerie Gunchick, Pooja Parikh
Publikováno v:
Nature metabolism
Branched-chain amino acids (BCAAs) supply both carbon and nitrogen in pancreatic cancers, and increased levels of BCAAs have been associated with increased risk of pancreatic ductal adenocarcinomas (PDACs). It remains unclear, however, how stromal ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90688c5693ce858c328142a7612e9409
http://europepmc.org/articles/PMC7438275
http://europepmc.org/articles/PMC7438275
Autor:
Thomas Hadlock, Sarah Owen, Venkateshwar G. Keshamouni, Sunitha Nagrath, Mina Zeinali, Yoon-Tae Kang, Zeqi Niu, Emma Purcell, Nithya Ramnath, Rishindra M. Reddy, Ting-Wen Lo
Publikováno v:
Advanced Science, Vol 8, Iss 6, Pp n/a-n/a (2021)
Advanced Science
Advanced Science
As the recognition between natural killer (NK) cells and cancer cells does not require antigen presentation, NK cells are being actively studied for use in adoptive cell therapies in the rapidly evolving armamentarium of cancer immunotherapy. In addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61930a4b6bec702b4ec996d97736594
https://doaj.org/article/1fe86000dcdb48de8238d16d2b30f982
https://doaj.org/article/1fe86000dcdb48de8238d16d2b30f982
Autor:
Sunitha Nagrath, Shamileh Fouladdel, Ting-Wen Lo, Yoon-Tae Kang, Alison B. Durham, Monica De Silva Raguera, Vasudha Murlidhar, Heather Fairbairn, Emma Purcell, Thomas Hadlock, Anusha Mutukuri, Scott A. McLean
Publikováno v:
Advanced Science, Vol 7, Iss 19, Pp n/a-n/a (2020)
Advanced Science
Advanced Science
Melanoma is among the most aggressive cancers, and its rate of incidence continues to grow. Early detection of melanoma has been hampered due to the lack of promising markers for testing. Recent advances in liquid biopsy have proposed noninvasive alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfa0d3d4d7cb8bcdb75ae92eb4dcbd1
https://doaj.org/article/2478a8956f83442dae965a06016983c9
https://doaj.org/article/2478a8956f83442dae965a06016983c9