Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Ting Lim"'
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/e0617b1d20174c67b17340e2ad076255
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Epitranscriptomic RNA modifications are crucial for the maintenance of glioma stem cells (GSCs), the most malignant cells in glioblastoma (GBM). 3-methylcytosine (m3C) is a new epitranscriptomic mark on RNAs and METTL8 represents an m3C writ
Externí odkaz:
https://doaj.org/article/1d37dfa6251d462ab7c00e54f1198368
Autor:
Sungwon Yoon, Hendra Goh, Phong Ching Lee, Hong Chang Tan, Ming Ming Teh, Dawn Shao Ting Lim, Ann Kwee, Chandran Suresh, David Carmody, Du Soon Swee, Sarah Ying Tse Tan, Andy Jun-Wei Wong, Charlotte Hui-Min Choo, Zongwen Wee, Yong Mong Bee
Publikováno v:
JMIR Human Factors, Vol 11, p e50939 (2024)
BackgroundThe clinical management of type 2 diabetes mellitus (T2DM) presents a significant challenge due to the constantly evolving clinical practice guidelines and growing array of drug classes available. Evidence suggests that artificial intellige
Externí odkaz:
https://doaj.org/article/75f1edfdb597430caf02360429490857
Autor:
Lopez, Shaun Eric1 shaun_eric_lopez@ttsh.com.sg, Xue Ting Lim, Rachel1
Publikováno v:
Annals of the Academy of Medicine, Singapore. May2024, Vol. 53 Issue 5, p334-337. 4p.
Autor:
Ting, Lim Sin1 (AUTHOR), Zailani, Suhaiza1 (AUTHOR), Sidek, Noor Zahirah Mohd2 (AUTHOR) nzahirah@uitm.edu.my, Shaharudin, Mohd Rizaimy3 (AUTHOR)
Publikováno v:
Environment, Development & Sustainability. Jul2024, Vol. 26 Issue 7, p17551-17578. 28p.
Autor:
Hui Xing Tan, Rachel Li Ting Lim, Pei San Ang, Belinda Pei Qin Foo, Yen Ling Koon, Jing Wei Neo, Amelia Jing Jing Ng, Siew Har Tan, Desmond Chun Hwee Teo, Mun Yee Tham, Aaron Jun Yi Yap, Nicholas Kai Ming Ng, Celine Wei Ping Loke, Li Fung Peck, Huilin Huang, Sreemanee Raaj Dorajoo
Publikováno v:
Pharmacoepidemiology, Vol 2, Iss 3, Pp 223-235 (2023)
Background: Identifying patients with diabetes mellitus (DM) is often performed in epidemiological studies using electronic health records (EHR), but currently available algorithms have features that limit their generalizability. Methods: We develope
Externí odkaz:
https://doaj.org/article/3715f76dc6f242cdb5b5f42608799fa4
Autor:
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw M. Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Using cancer cell lines and patient-derived tumor organoids, we demonstrate that loss of the negative elongation factor (NELF) complex inhibits bre
Externí odkaz:
https://doaj.org/article/cb2e731233234766a276c66996f09b7a
Autor:
Sarah Ying Tse Tan, Hong Chang Tan, Ling Zhu, Lih Ming Loh, Dawn Shao Ting Lim, Du Soon Swee, Yoke Ling Chan, Huee Boon Lim, Shiau Lee Ling, En Jun Ou, Wynn Ee Teo, Xiao Ping Zhang, Hui Fen Goh, Peng Chin Kek
Publikováno v:
Endocrine Connections, Vol 12, Iss 4, Pp 1-9 (2023)
Background: Adrenal insufficiency (AI) is potentially life-threatening, and accurate diagnosis is crucial. The first-line diagnostic test, the adreno corticotrophic hormone (ACTH) stimulation test, measures serum total cortisol. However , this is aff
Externí odkaz:
https://doaj.org/article/eed17e557442425db78451d79a70d10b
Autor:
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Lum, Wai Kit Cheong, Khay Guan Yeoh, Ker Kan Tan, Radoslaw M. Sobota, Chandra S. Verma, David P. Lane, Wai Leong Tam, Ashok R. Venkitaraman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Here the authors identify distinct mechanisms by which domain-specific p53 mutations activate cancer cell growth via the epidermal growth factor receptor (EGFR). These mechanisms affect sensitivity to EGFR inhibitors, opening avenues for targeted the
Externí odkaz:
https://doaj.org/article/887b89f317fb487d8e09152d6d299ac4
Autor:
Maxine S. Y. Lam, Jose Antonio Reales-Calderon, Jin Rong Ow, Joey J. Y. Aw, Damien Tan, Ragavi Vijayakumar, Erica Ceccarello, Tommaso Tabaglio, Yan Ting Lim, Wang Loo Chien, Fritz Lai, Anthony Tan Tanoto, Qingfeng Chen, Radoslaw M. Sobota, Giulia Adriani, Antonio Bertoletti, Ernesto Guccione, Andrea Pavesi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Engineered T cells are used for tumour immunotherapy but can have side effects and need multiple treatment rounds. Here during expansion of T cells from patients, the authors use an inhibitor of the epigenetic regulator G9a/GLP and show that this inc
Externí odkaz:
https://doaj.org/article/710a463b245b4976ac0ed03cff323a5d