Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ting‐Wei Mi"'
Autor:
Ya-Jie Xu, Pei-Pei Liu, Zhong-Ze Yan, Ting-Wei Mi, Ying-Ying Wang, Qian Li, Zhao-Qian Teng, Chang-Mei Liu
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Rett syndrome (RTT), mainly caused by mutations in methyl-CpG binding protein 2 (MECP2), is one of the most prevalent neurodevelopmental disorders in girls. However, the underlying mechanism of MECP2 remains largely unknown and cu
Externí odkaz:
https://doaj.org/article/9141a8097db34f22a03cf62751e12afa
Autor:
Pei‐Pei Liu, Shang‐Kun Dai, Ting‐Wei Mi, Gang‐Bin Tang, Zhuo Wang, Hui Wang, Hong‐Zhen Du, Yi Tang, Zhao‐Qian Teng, Chang‐Mei Liu
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-20 (2022)
Abstract Mutations in AT‐rich interactive domain‐containing protein 1A (ARID1A) cause Coffin‐Siris syndrome (CSS), a rare genetic disorder that results in mild to severe intellectual disabilities. However, the biological role of ARID1A in the b
Externí odkaz:
https://doaj.org/article/b4f7592562874eeaa694011fbfd342d4
Autor:
Gang-Bin Tang, Ting-Wei Mi, Man-Lian Sun, Ya-Jie Xu, Shu-Guang Yang, Hong-Zhen Du, Saijilafu, Zhao-Qian Teng, Jun Gao, Chang-Mei Liu
Publikováno v:
IBRO Reports, Vol 9, Iss , Pp 138-146 (2020)
5-hydroxytryptamine receptor 5B (5-HT5B) is a gene coding for a G protein-coupled receptor (GPCR) that plays key roles in several neurodevelopmental disorders. Our previous study showed that disruption of 5-HT5B induced by lysine (K)-specific demethy
Externí odkaz:
https://doaj.org/article/6a8a5c290771421b8c062027f8d81ad3
Autor:
Hai-Liang Yan, Xiao-Wen Sun, Zhi-Meng Wang, Pei-Pei Liu, Ting-Wei Mi, Cong Liu, Ying-Ying Wang, Xuan-Cheng He, Hong-Zhen Du, Chang-Mei Liu, Zhao-Qian Teng
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Anxiety and depression are major public health concerns worldwide. Although genome-wide association studies have identified several genes robustly associated with susceptibility for these disorders, the molecular and cellular mechanisms associated wi
Externí odkaz:
https://doaj.org/article/7ea23fde36ed48b88a71e50a8f8be7e0
Autor:
Gang-Bin Tang, Yu-Qiang Zeng, Pei-Pei Liu, Ting-Wei Mi, Shuang-Feng Zhang, Shang-Kun Dai, Qing-Yuan Tang, Lin Yang, Ya-Jie Xu, Hai-Liang Yan, Hong-Zhen Du, Zhao-Qian Teng, Feng-Quan Zhou, Chang-Mei Liu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Histone demethylase UTX mediates removal of repressive trimethylation of histone H3 lysine 27 (H3K27me3) to establish a mechanistic switch to activate large sets of genes. Mutation of Utx has recently been shown to be associated with Kabuki syndrome,
Externí odkaz:
https://doaj.org/article/037be87e5a04453da1ac2fe5de07e87e
Autor:
Ya-Jie Xu, Zhao-Qian Teng, Gang-Bin Tang, Ting-Wei Mi, Jun Gao, Saijilafu, Hong-Zhen Du, Chang-Mei Liu, Man-Lian Sun, Shu-Guang Yang
Publikováno v:
IBRO Reports, Vol 9, Iss, Pp 138-146 (2020)
IBRO Reports
IBRO Reports
5-hydroxytryptamine receptor 5B (5-HT5B) is a gene coding for a G protein-coupled receptor (GPCR) that plays key roles in several neurodevelopmental disorders. Our previous study showed that disruption of 5-HT5B induced by lysine (K)-specific demethy
Autor:
Xuan-Cheng He, Shuang-Feng Zhang, Cong Liu, Ting-Wei Mi, Hong-Zhen Du, Zhao-Qian Teng, Zhi-Meng Wang, Xiao-Wen Sun, Chang-Mei Liu, Ying-Ying Wang
Publikováno v:
Experimental Neurobiology
Neuropsychiatric disorders are the leading cause of mental and intellectual disabilities worldwide. Current therapies against neuropsychiatric disorders are very limited, and very little is known about the onset and development of these diseases, and
Autor:
Ying-Ying Wang, Yu-Sen Deng, Shang-Kun Dai, Ting-Wei Mi, Rui-Yang Li, Pei-Pei Liu, Cong Liu, Bao-Dong He, Xuan-Cheng He, Hong-Zhen Du, Han-Chen Yang, Yi Tang, Chang-Mei Liu, Zhao-Qian Teng
Publikováno v:
Molecular psychiatry. 27(7)
The embryonic ectoderm development (EED) is a core component of the polycomb-repressive complex 2 (PRC2) whose mutations are linked to neurodevelopmental abnormalities, intellectual disability, and neurodegeneration. Although EED has been extensively
Autor:
Ying-Ying Wang, Yu-Sen Deng, Shang-Kun Dai, Ting-Wei Mi, Rui-Yang Li, Pei-Pei Liu, Cong Liu, Bao-Dong He, Xuan-Cheng He, Hong-Zhen Du, Han-Chen Yang, Yi Tang, Chang-Mei Liu, Zhao-Qian Teng
Publikováno v:
Molecular Psychiatry. 27:2915-2915
Autor:
Wei Xie, Peng Jin, Bing Bai, Zhenping Chen, Yuxin Li, Ying Cheng, Zhi-Meng Wang, Yunhee Kang, Xiaona Wang, Zuo-Lun Chen, Chang-Mei Liu, Zhi-Jie Dai, Ting-Wei Mi, Ying-Ying Wang, Weiqi Tan, Cong Liu, Shuting Xia, An Liu, Xusheng Wang, Shuang-Feng Zhang, Zhao-Qian Teng, Qinmiao Sun, Yujing Li, Hong Wang, Nina Xie, Zikai Zhou, Dahua Chen, Junmin Peng, Hai-Liang Yan, Li Lin, Gang-Bin Tang
Publikováno v:
Nature neuroscience
Genetic analyses have linked microRNA-137 (MIR137) to neuropsychiatric disorders, including schizophrenia and autism spectrum disorder. miR-137 plays important roles in neurogenesis and neuronal maturation, but the impact of miR-137 loss-of-function