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DNA supercoiling has emerged as a major contributor to gene regulation in bacteria. The impact of DNA supercoiling on transcription dynamics in eukaryotes is less clear. Here, using single-molecule dual-color RNA imaging in budding yeast, we show tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46f9f6376208fcefee6f5ba8b7fa83e6
https://doi.org/10.1101/2022.03.04.482969
https://doi.org/10.1101/2022.03.04.482969
Autor:
Abigail Figueroa, Iris L. Torres, Julianna Goelzer, Michael Pool, Tineke Lenstra, Matthew L. Ferguson
Publikováno v:
Biophysical Journal. 118:467a
Autor:
Ioannis Tsirkas, Daniel Dovrat, Manikandan Thangaraj, Ineke Brouwer, Amit Cohen, Zohar Paleiov, Michael M Meijler, Tineke Lenstra, Amir Aharoni
Publikováno v:
Nucleic Acids Research. 50(4):2143-2156
The coexistence of DNA replication and transcription during S-phase requires their tight coordination to prevent harmful conflicts. While extensive research revealed important mechanisms for minimizing these conflicts and their consequences, little i