Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Tindaro, Giardina"'
Autor:
Leslie Calapre, Tindaro Giardina, Aaron B. Beasley, Anna L. Reid, Colin Stewart, Benhur Amanuel, Tarek M. Meniawy, Elin S. Gray
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Plasma circulating tumour DNA (ctDNA) has been suggested to be a viable biomarker of response to treatment in patients with high grade serous ovarian carcinoma (HGSOC). TP53 mutations are present in more than 90% of HGSOCs but somatic varian
Externí odkaz:
https://doaj.org/article/4563136ea8714a7294842de73f101b88
Autor:
Leslie Calapre, Tindaro Giardina, Cleo Robinson, Anna L. Reid, Zeyad Al‐Ogaili, Michelle R. Pereira, Ashleigh C. McEvoy, Lydia Warburton, Nicholas K. Hayward, Muhammad A. Khattak, Tarek M. Meniawy, Michael Millward, Benhur Amanuel, Melanie Ziman, Elin S. Gray
Publikováno v:
Molecular Oncology, Vol 13, Iss 2, Pp 171-184 (2019)
Circulating tumor DNA (ctDNA) may serve as a surrogate to tissue biopsy for noninvasive identification of mutations across multiple genetic loci and for disease monitoring in melanoma. In this study, we compared the mutation profiles of tumor biopsie
Externí odkaz:
https://doaj.org/article/98c3acf65a924037b07e2a94d106762e
Autor:
Amanda M. Ireland, Tamazin N. Leecy, Benjamin A. Wood, Bob Mirzai, Tindaro Giardina, Nima Mesbah Ardakani
Publikováno v:
The American Journal of dermatopathology. 44(11)
Merkel cell carcinoma with a sarcomatous component is very rare, with only 12 cases reported in the literature, often with overtly malignant myoid differentiation. We report a case of metastatic Merkel cell carcinosarcoma presenting in a lymph node 6
Autor:
Leslie, Calapre, Tindaro, Giardina, Aaron B, Beasley, Anna L, Reid, Colin, Stewart, Benhur, Amanuel, Tarek M, Meniawy, Elin S, Gray
Publikováno v:
Scientific reports. 13(1)
Plasma circulating tumour DNA (ctDNA) has been suggested to be a viable biomarker of response to treatment in patients with high grade serous ovarian carcinoma (HGSOC). TP53 mutations are present in more than 90% of HGSOCs but somatic variants are di
Autor:
Benjamin Y Kong, Hao-Wen Sim, Anna K Nowak, Sonia Yip, Elizabeth H Barnes, Bryan W Day, Michael E Buckland, Roel Verhaak, Terrance Johns, Cleo Robinson, Marc A Thomas, Tindaro Giardina, Zarnie Lwin, Andrew M Scott, Jonathon Parkinson, Rosalind Jeffree, Richard de Abreu Lourenco, Elizabeth J Hovey, Lawrence M Cher, Ganessan Kichendasse, Mustafa Khasraw, Merryn Hall, Emily Tu, Benhur Amanuel, Eng-Siew Koh, Hui K Gan
Publikováno v:
BMJ Open
IntroductionGrades 2 and 3 gliomas (G2/3 gliomas), when combined, are the second largest group of malignant brain tumours in adults. The outcomes for G2/3 gliomas at progression approach the dismal outcomes for glioblastoma (GBM), yet there is a pauc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bb9b52e6cfac2ecb5ea43d40f9f14e
https://hdl.handle.net/10453/152950
https://hdl.handle.net/10453/152950
Publikováno v:
Pathology. 51:116-120
Autor:
Tindaro Giardina, Timothy Humphries, Anna Reid, Nima MesbahArdakani, Cleo Robinson, Michael Millward, Elin Gray, Benhur Amanuel
Publikováno v:
Journal of Clinical Oncology. 40:e21570-e21570
e21570 Background: High tumor mutation burden (TMB) predicts improved efficacy of immune checkpoint inhibitors (ICIs) across a range of malignancies, including melanoma. Circulating tumor DNA (ctDNA) has emerged as a powerful complement to tumor biop
Autor:
Nicholas K. Hayward, Leslie Calapre, Michael Millward, Michelle R. Pereira, Elin S. Gray, Cleo Robinson, Tarek Meniawy, Benhur Amanuel, Zeyad Al-Ogaili, Tindaro Giardina, Ashleigh C. McEvoy, Muhammad A. Khattak, Anna L. Reid, Lydia Warburton, Melanie Ziman
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 2, Pp 171-184 (2019)
Molecular Oncology, Vol 13, Iss 2, Pp 171-184 (2019)
Circulating tumor DNA (ctDNA) may serve as a surrogate to tissue biopsy for noninvasive identification of mutations across multiple genetic loci and for disease monitoring in melanoma. In this study, we compared the mutation profiles of tumor biopsie
Autor:
Cleo Robinson, Terrance Grant Johns, Tindaro Giardina, Emily Tu, Marc A. Thomas, Rosalind L. Jeffree, Bryan W. Day, Anna K. Nowak, Mark Rosenthal, Elizabeth Hovey, Sonia Yip, Andrew M. Scott, Ganessan Kichendasse, Hao-Wen Sim, Eng-Siew Koh, Benjamin Y. Kong, Richard De Abreu Lourenco, Benhur Amanuel, Mustafa Khasraw, Roel G.W. Verhaak, Peter Lau, Zarnie Lwin, Lawrence Cher, James R. Whittle, Elizabeth H Barnes, Hui K Gan, Jonathon Parkinson, Michael E. Buckland, Merryn Hall
Publikováno v:
Neuro-Oncology. 23:vi106-vi107
BACKGROUND Grade 2 and 3 (G2/3) gliomas are the second largest group of brain tumors in adults. Although the prognosis for G2/3 gliomas at the time of relapse mirror those of glioblastoma, there are few trials in this space. METHODS LUMOS was a natio
Autor:
Dominic V. Spagnolo, Michael Millward, Benhur Amanuel, Fabienne Grieu-Iacopetta, Barry Iacopetta, Tindaro Giardina, Cleo Robinson
Publikováno v:
Pathology. 50:389-401
The introduction of next generation sequencing (NGS) in the routine diagnostic setting is still in the development phase and has been limited by its complexity. Targeted NGS offers an attractive alternative to performing multiple single target assays