Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tina ZAVAŠNIK-BERGANT"'
Autor:
Tina Zavašnik-Bergant, Robert Vidmar, Andreja Sekirnik, Marko Fonović, Jiří Salát, Lenka Grunclová, Petr Kopáček, Boris Turk
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
To ensure successful feeding tick saliva contains a number of inhibitory proteins that interfere with the host immune response and help to create a permissive environment for pathogen transmission. Among the potential targets of the salivary cystatin
Externí odkaz:
https://doaj.org/article/1f4e448840424b1a869c507907d453e8
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150815 (2016)
Dendritic cells (DC) play a pivotal role as antigen presenting cells (APC) and their maturation is crucial for effectively eliciting an antigen-specific immune response. The p41 splice variant of MHC class II-associated chaperone, called invariant ch
Externí odkaz:
https://doaj.org/article/1bfbd1212f074f949f5eb49ceda406e6
Autor:
Mira Polajnar, Tina Zavašnik-Bergant, Katja Škerget, Matej Vizovišek, Robert Vidmar, Marko Fonović, Nataša Kopitar-Jerala, Uroš Petrovič, Susanna Navarro, Salvador Ventura, Eva Žerovnik
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102500 (2014)
Alternative functions, apart from cathepsins inhibition, are being discovered for stefin B. Here, we investigate its role in vesicular trafficking and autophagy. Astrocytes isolated from stefin B knock-out (KO) mice exhibited an increased level of pr
Externí odkaz:
https://doaj.org/article/0c2e2baad3164651bb16ea11b2e11b51
Autor:
Miha Butinar, Tina Zavašnik Bergant, Nežka Kavčič, Andreja Bratovš, Maruša Hafner Česen, Thomas Reinheckel, Boris Turk, Barbara Sobotič, Ana Petelin, Lea Bojič
Publikováno v:
The FEBS Journal. 287:5148-5166
L-leucyl-leucine methyl ester (LLOMe) is a lysosomotropic detergent, which was evaluated in clinical trials in graft-vs-host disease because it very efficiently killed monocytic cell lines. It was also shown to efficiently trigger apoptosis in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247b1d45c962a1c7fec653cb7e9c87a7
https://doi.org/10.1111/febs.15326
https://doi.org/10.1111/febs.15326
Autor:
Urska Repnik, Marija Vukomanović, Tina Zavašnik-Bergant, Srečo D. Škapin, Rok Kostanjšek, Danilo Suvorov
Publikováno v:
ACS biomaterials scienceengineering. 1(10)
Because of the abounded presence of the silver-containing products in the market and intensively studied silver-containing biomaterials in the literature, we investigated a hypothesis that stabilizing silver within bioactive hydroxyapatite composite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3a2b7bec4489b71ac44d4b0ec00e9b
https://pubmed.ncbi.nlm.nih.gov/33429525
https://pubmed.ncbi.nlm.nih.gov/33429525
Autor:
Mira Polajnar, Magda Tušek-Žnidarič, Eva Žerovnik, Nataša Kopitar-Jerala, Tina Zavašnik-Bergant
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1843:2089-2099
EPM1 is a rare progressive myoclonus epilepsy accompanied by apoptosis in the cerebellum of patients. Mutations in the gene of stefin B (cystatin B) are responsible for the primary defect underlying EPM1. Taking stefin B aggregates as a model we aske
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f9976881616a76d7473f673ef7db0b
https://doi.org/10.1016/j.bbamcr.2014.05.018
https://doi.org/10.1016/j.bbamcr.2014.05.018
Autor:
Marko Mihelič, Veronika Stoka, Barbara Jerič, Tina Zavašnik-Bergant, Gregor Gunčar, Martina Klarić, Boris Turk, Vito Turk, Iztok Dolenc
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833:2254-2266
The contribution of individual cysteine cathepsins as positive mediators of programmed cell death is dependent on several factors, such as the type of stimuli, intensity and duration of the stimulus, and cell type involved. Of the eleven human cystei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9792b9a94763cad095e5a8ae47d8cc
https://doi.org/10.1016/j.bbamcr.2013.05.007
https://doi.org/10.1016/j.bbamcr.2013.05.007
Autor:
Tina Zavašnik-Bergant, Urska Repnik, Robert Layfield, Slavko Čeru, Vito Turk, Nataša Kopitar-Jerala, Eva Žerovnik
Publikováno v:
Biology of the Cell. 102:319-334
Background. Protein aggregation is a major contributor to the pathogenic mechanisms of human neurodegenerative diseases. Mutations in the CSTB (cystatin B) gene [StB (stefin B)] cause EPM1 (progressive myoclonus epilepsy of type 1), an epilepsy syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb324f3a7272905af5b8d316092693b
https://doi.org/10.1042/bc20090163
https://doi.org/10.1042/bc20090163
Autor:
Boris Turk, Tina Zavašnik-Bergant
Publikováno v:
bchm. 388:1141-1149
Cysteine proteases (cathepsins) play a pivotal role in various physiological processes, as well as in several diseases. In the immune response, maturation of major histocompatibility class II (MHC II) molecules and processing of antigens for further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94f523b14f5d09bd2ad1d1626640d64
https://doi.org/10.1515/bc.2007.144
https://doi.org/10.1515/bc.2007.144
Autor:
Adaleta Mulaomerović, Lejla Begić, Alma Halilbasic, Janko Kos, Tina Zavašnik-Bergant, Elmir Čičkušić
Publikováno v:
Cancer Letters. 248:192-197
The concentration of cysteine protease inhibitor cystatin C was determined in sera from 59 patients with non-Hodgkin B-cell lymphoma using ELISA. The sera from 43 age and sex matched healthy blood donors served as controls. Cystatin C was significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d749343452d746466e018f524270862
https://doi.org/10.1016/j.canlet.2006.07.004
https://doi.org/10.1016/j.canlet.2006.07.004