Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tina Xiang"'
Autor:
Tiffany Tate, Tina Xiang, Sarah E. Wobker, Mi Zhou, Xiao Chen, Hyunwoo Kim, Ekatherina Batourina, Chyuan-Sheng Lin, William Y. Kim, Chao Lu, James M. Mckiernan, Cathy Lee Mendelsohn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
PPARg is differentially expressed in bladder cancer subtypes. Here, the authors show in mice that when an activated form of PPARg is expressed in basal bladder cells tumours do not form, however in the presence of injury the basal cells differentiate
Externí odkaz:
https://doaj.org/article/458eca01a6e54249ad6eb5780e7e2e46
Autor:
Chang Liu, Tiffany Tate, Ekatherina Batourina, Steven T. Truschel, Steven Potter, Mike Adam, Tina Xiang, Martin Picard, Maia Reiley, Kerry Schneider, Manuel Tamargo, Chao Lu, Xiao Chen, Jing He, Hyunwoo Kim, Cathy Lee Mendelsohn
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The nuclear receptor Pparg regulates urothelial differentiation in vitro but its role in healthy urothelium is unclear. Here, the authors show that PPAR gamma mediates urothelial development during both homeostasis (via mitochondrial function) and fo
Externí odkaz:
https://doaj.org/article/303531835cbf4da28f7e0d26a90b094e
Publikováno v:
Development. 149
The urothelium of the bladder functions as a waterproof barrier between tissue and outflowing urine. Largely quiescent during homeostasis, this unique epithelium rapidly regenerates in response to bacterial or chemical injury. The specification of th
Publikováno v:
Development (09501991); May2022, Vol. 149 Issue 9, p1-10, 10p
Autor:
Martin Picard, Xiao Chen, Maia Reiley, Jing He, S. Steven Potter, Kerry Schneider, Cathy Mendelsohn, Manuel A. Tamargo, Hyunwoo Kim, Tiffany Tate, Mike Adam, Chao Lu, Chang Liu, Ekatherina Batourina, Steven T. Truschel, Tina Xiang
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The urothelium is an epithelial barrier lining the bladder that protects against infection, fluid exchange and damage from toxins. The nuclear receptor Pparg promotes urothelial differentiation in vitro, and Pparg mutations are associated with bladde