Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tina Van Den Broeck"'
Autor:
Rienk Nieuwland, Tina Van Den Broeck, Leonie de Rond, Ton G. van Leeuwen, Frank A. W. Coumans, Edwin van der Pol, Paul R. Bloemen, Ludo Monheim
Publikováno v:
Cytometry
Cytometry. Part A, 97(6), 582-591. Wiley-Liss Inc.
Cytometry. Part A, 97(6), 582-591. Wiley-Liss Inc.
Extracellular vesicles (EVs) are commonly studied by flow cytometry. Due to their small size and low refractive index, the scatter intensity of most EVs is below the detection limit of common flow cytometers. Here, we aim to improve forward scatter (
Publikováno v:
bioRxiv.
Autor:
Christopher Bassford, Tina Van Den Broeck, Gert Boschman, Bryan Yates, A. John Simpson, Vanessa Linnett, Niall Anderson, Daniel F. McAuley, Jonathan Hulme, Jennie Parker, Cecilia M O'Kane, Gavin D. Perkins, Julian Sonksen, Anthony J. Rostron, Glenn Phair, Ashley Agus, Bronagh Blackwood, Suveer Singh, Lydia M Emerson, Kallirroi Kefala, D W James Keenan, Alistair I Roy, Ronan McMullan, Shondipon Laha, Timothy S. Walsh, Stephen Bonner, Nicole M Robin, Simon Baudouin, Paul Dark, Susan A Bowett, Ingeborg Welters, Ross L Paterson, Craig Spencer, Jonathan Scott, A Joy Allen, Jonathan Bannard-Smith, Thomas P Hellyer, Andrew Conway Morris, Stephen E Wright
Publikováno v:
Hellyer, T P, McAuley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, D W J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia ', Annals of Translational Medicine, vol. 8, no. 13, pp. 840 . https://doi.org/10.21037/atm-20-3701
Ann Transl Med
ANNALS OF TRANSLATIONAL MEDICINE
Ann Transl Med
ANNALS OF TRANSLATIONAL MEDICINE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f0c723a63b6a59126a0f7be7f8a2cf
https://pure.qub.ac.uk/en/publications/more-research-is-required-to-understand-factors-influencing-antibiotic-prescribing-in-complex-conditions-like-suspected-ventilatorassociated-pneumonia(564316aa-c89d-4960-b344-374989c640ea).html
https://pure.qub.ac.uk/en/publications/more-research-is-required-to-understand-factors-influencing-antibiotic-prescribing-in-complex-conditions-like-suspected-ventilatorassociated-pneumonia(564316aa-c89d-4960-b344-374989c640ea).html
Autor:
D W James Keenan, Alistair I Roy, Ronan McMullan, Ashley Agus, Niall Anderson, Gert Boschman, Christopher Bassford, Stephen E Wright, Jonathan Scott, Anthony J. Rostron, A. John Simpson, Nicole M Robin, Cecilia O'Kane, Vanessa Linnett, Simon Baudouin, Ingeborg Welters, Jonathan Hulme, Susan A Bowett, Glenn Phair, Lydia M Emerson, Daniel F. McAuley, A Joy Allen, Julian Sonksen, Bronagh Blackwood, Paul Dark, Ross L Paterson, Kallirroi Kefala, Stephen Bonner, Gavin D. Perkins, Bryan Yates, Tina Van Den Broeck, Jennie Parker, Shondipon Laha, Timothy S. Walsh, Craig Spencer, Thomas P Hellyer, Suveer Singh, Jonathan Bannard-Smith, Andrew Conway Morris
Publikováno v:
LANCET RESPIRATORY MEDICINE
Hellyer, T P, Mcauley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, Mcmullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, D J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine . https://doi.org/10.1016/S2213-2600(19)30367-4
Ann Transl Med
Hellyer, T P, McAuley, D, Walsh, T S, Anderson, N H, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C, Baudouin, S V, Paterson, R W, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N, Welters, I, Bassford, C, Yates, B, Spencer, C, Laha, S, Hulme, J, Bonner, S, Linnett, V C, Sonksen, J, van den Broeck, T, Boschman, G, Keenan, J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2019, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine, vol. 8, no. 2, pp. 182 . https://doi.org/10.1016/S2213-2600(19)30367-4
Hellyer, T P, McAuley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, DW J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine, vol. 8, no. 2, pp. 182-191 . https://doi.org/10.1016/S2213-2600(19)30367-4
Hellyer, T P, Mcauley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, Mcmullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, D J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine . https://doi.org/10.1016/S2213-2600(19)30367-4
Ann Transl Med
Hellyer, T P, McAuley, D, Walsh, T S, Anderson, N H, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C, Baudouin, S V, Paterson, R W, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N, Welters, I, Bassford, C, Yates, B, Spencer, C, Laha, S, Hulme, J, Bonner, S, Linnett, V C, Sonksen, J, van den Broeck, T, Boschman, G, Keenan, J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2019, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine, vol. 8, no. 2, pp. 182 . https://doi.org/10.1016/S2213-2600(19)30367-4
Hellyer, T P, McAuley, D F, Walsh, T S, Anderson, N, Conway Morris, A, Singh, S, Dark, P, Roy, A I, Perkins, G D, McMullan, R, Emerson, L M, Blackwood, B, Wright, S E, Kefala, K, O'Kane, C M, Baudouin, S V, Paterson, R L, Rostron, A J, Agus, A, Bannard-Smith, J, Robin, N M, Welters, I D, Bassford, C, Yates, B, Spencer, C, Laha, S K, Hulme, J, Bonner, S, Linnett, V, Sonksen, J, Van Den Broeck, T, Boschman, G, Keenan, DW J, Scott, J, Allen, A J, Phair, G, Parker, J, Bowett, S A & Simpson, A J 2020, ' Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation ', The Lancet Respiratory Medicine, vol. 8, no. 2, pp. 182-191 . https://doi.org/10.1016/S2213-2600(19)30367-4
Background: Ventilator-associated pneumonia is the most common intensive care unit (ICU)-acquired infection, yet accurate diagnosis remains difficult, leading to overuse of antibiotics. Low concentrations of IL-1β and IL-8 in bronchoalveolar lavage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0819679fdb81603ef968776dfb2fb3b4
http://hdl.handle.net/10044/1/82700
http://hdl.handle.net/10044/1/82700
Autor:
Els Van Ammel, Tessa Kerre, Bart Vandekerckhove, Tina Van Den Broeck, Georges Leclercq, Maarten Delforche, Sylvie Taveirne, Tom Taghon, Jean Plum
Publikováno v:
The Journal of Immunology. 190:1982-1990
The Ly49 NK receptor family in mice is composed of several members that recognize MHC class I (MHC-I) or MHC-I–related molecules. We and others have shown before that Ly49E is a unique member, with a different expression pattern on NK cells and bei
Autor:
Thomas P. Hellyer, Niall H. Anderson, Jennie Parker, Paul Dark, Tina Van Den Broeck, Suveer Singh, Ronan McMullan, Ashley M. Agus, Lydia M. Emerson, Bronagh Blackwood, Savita Gossain, Tim S. Walsh, Gavin D. Perkins, Andrew Conway Morris, Daniel F. McAuley, A. John Simpson
Publikováno v:
Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Morris, A C, McAuley, D F & Simpson, A J 2016, ' Erratum to: 'Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial' ', Trials, vol. 17, no. 1, 465, pp. 1 . https://doi.org/10.1186/s13063-016-1594-8
Trials
Trials
Background Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ffdec3e180ea0756b4440785f79dc5
https://doi.org/10.1186/s13063-016-1594-8
https://doi.org/10.1186/s13063-016-1594-8
Autor:
Suveer Singh, Jennie Parker, Niall Anderson, Ashley Agus, Timothy S. Walsh, Gavin D. Perkins, Savita Gossain, Andrew Conway Morris, Lydia M Emerson, A. John Simpson, Thomas P Hellyer, Paul Dark, Tina Van Den Broeck, Bronagh Blackwood, Ronan McMullan, Daniel F. McAuley
Publikováno v:
Trials
Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Conway Morris, A, McAuley, D F & Simpson, A J 2016, ' Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2) : Study protocol for a randomised controlled trial ', Trials, vol. 17, no. 1, 318, pp. 318 . https://doi.org/10.1186/s13063-016-1442-x, https://doi.org/10.1186/s13063-016-1442-x
Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Conway Morris, A, McAuley, D F & Simpson, A J 2016, ' Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2) : study protocol for a randomised controlled trial ', Trials, vol. 17, no. 1, pp. 318 . https://doi.org/10.1186/s13063-016-1442-x
Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Conway Morris, A, McAuley, D F & Simpson, A J 2016, ' Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2) : Study protocol for a randomised controlled trial ', Trials, vol. 17, no. 1, 318, pp. 318 . https://doi.org/10.1186/s13063-016-1442-x, https://doi.org/10.1186/s13063-016-1442-x
Hellyer, T P, Anderson, N H, Parker, J, Dark, P, Van Den Broeck, T, Singh, S, McMullan, R, Agus, A M, Emerson, L M, Blackwood, B, Gossain, S, Walsh, T S, Perkins, G D, Conway Morris, A, McAuley, D F & Simpson, A J 2016, ' Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2) : study protocol for a randomised controlled trial ', Trials, vol. 17, no. 1, pp. 318 . https://doi.org/10.1186/s13063-016-1442-x
Ventilator-acquired pneumonia (VAP) is a common reason for antimicrobial therapy in the intensive care unit (ICU). Biomarker-based diagnostics could improve antimicrobial stewardship through rapid exclusion of VAP. Bronchoalveloar lavage (BAL) fluid
Autor:
Patrick Chames, Kieran Crosbie-Staunton, Adriele Prina-Mello, Omar K. Mahfoud, Bashir M. Mohamed, Tina Van Den Broeck, Stefan A. Maier, Yuri Volkov, Daniel Baty, Alyona Sukhanova, Line De Kimpe, Frauke Alves, Aliaksandra Rakovich, Tatsiana Rakovich, Igor Nabiev, Frans Nauwelaers
Publikováno v:
ACS Nano
ACS Nano, American Chemical Society, 2014, 8 (6), pp.5682-5695. ⟨10.1021/nn500212h⟩
ACS Nano, 2014, 8 (6), pp.5682-5695. ⟨10.1021/nn500212h⟩
ACS Nano, American Chemical Society, 2014, 8 (6), pp.5682-5695. ⟨10.1021/nn500212h⟩
ACS Nano, 2014, 8 (6), pp.5682-5695. ⟨10.1021/nn500212h⟩
International audience; Despite the widespread availability of immunohistochemical and other methodologies for screening and early detection of lung and breast cancer biomarkers, diagnosis of the early stage of cancers can be difficult and prone to e
Autor:
Daniel H. Kaplan, Jean Plum, Bart Vandekerckhove, Tom Taghon, Björn E. Clausen, Sylvie Taveirne, Tina Van Den Broeck, Georges Leclercq, Clare L. Bennett, Veerle De Colvenaer, Els Van Ammel
Publikováno v:
Journal of Leukocyte Biology, 90(1), 61-68. John Wiley & Sons Inc.
Journal of Leukocyte Biology, 90(1), 61-68. FEDERATION AMER SOC EXP BIOL
Journal of Leukocyte Biology, 90(1), 61-68. FEDERATION AMER SOC EXP BIOL
This study tested the hypothesis that V gamma 3 TCR-bearing T cells are influenced by LCs. V gamma 3 T cells and LCs are located in the epidermis of mice. V gamma 3 T cells represent the main T cell population in the skin epithelium and play a crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba8bc23f5edd2caf4aa31b964a9d306
https://pure.eur.nl/en/publications/26b5905b-fcca-4e90-a810-0bccccd5b225
https://pure.eur.nl/en/publications/26b5905b-fcca-4e90-a810-0bccccd5b225
Autor:
Tom Taghon, Christel Vangestel, Werner Held, Jean Plum, Tina Van Den Broeck, Veronique Debacker, Frederick Stevenaert, Mieke Dewerchin, Sylvie Taveirne, Bart Vandekerckhove, Patrick Matthys, Georges Leclercq, Wayne M. Yokoyama
Publikováno v:
Blood. 112(13)
The Ly49 natural killer (NK)–cell receptor family comprises both activating and inhibitory members, which recognize major histocompatibility complex (MHC) class I or MHC class I–related molecules and are involved in target recognition. As previou