Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tina Stark"'
Publikováno v:
Geriatrics, Vol 9, Iss 4, p 102 (2024)
Little is known about the healthy aging of the circadian timing system under natural living conditions. This study explores changes in the circadian rhythm of distal skin temperature (DST) with aging and relates these changes to sleep–wake timing a
Externí odkaz:
https://doaj.org/article/0697c6bb9ab5439d913770fc014472b5
Autor:
Tobias Lieblein, Rene Zangl, Janosch Martin, Jan Hoffmann, Marie J Hutchison, Tina Stark, Elke Stirnal, Thomas Schrader, Harald Schwalbe, Nina Morgner
Publikováno v:
eLife, Vol 9 (2020)
The formation of oligomers of the amyloid-β peptide plays a key role in the onset of Alzheimer's disease. We describe herein the investigation of disease-relevant small amyloid-β oligomers by mass spectrometry and ion mobility spectrometry, reveali
Externí odkaz:
https://doaj.org/article/ba34516caffd466fb9295cff7f883d7f
Autor:
Nina Morgner, Gunter P. Eckert, Tobias Lieblein, Maximilian Pohland, Mike Heilemann, Petra Freund, Rene Zangl, Rekha Grewal, Tina Stark, Elisabeth Kalden, Michael W. Göbel
Publikováno v:
Biochemistry. 56:4840-4849
The peptide sequence KLVFF resembles the hydrophobic core of the Aβ peptide known to form amyloid plaques in Alzheimer’s disease. Starting from its retro-inverso peptide, we have synthesized three generations of peptidomimetics. Step by step natur
Autor:
Tina, Stark, Tobias, Lieblein, Maximilian, Pohland, Elisabeth, Kalden, Petra, Freund, René, Zangl, Rekha, Grewal, Mike, Heilemann, Gunter P, Eckert, Nina, Morgner, Michael W, Göbel
Publikováno v:
Biochemistry. 56(36)
The peptide sequence KLVFF resembles the hydrophobic core of the Aβ peptide known to form amyloid plaques in Alzheimer's disease. Starting from its retro-inverso peptide, we have synthesized three generations of peptidomimetics. Step by step natural
Publikováno v:
Synlett. 24:2730-2734
A variety of substituted aromatic systems are synthesized by the Catellani reaction. These are used as precursors for novel amino acids with a basic side chain.
Autor:
Mihaela Cernescu, Bernhard Brutschy, Kristina Leuner, Christopher Kurz, Gunter P. Eckert, Elisabeth Kalden, Michael W. Göbel, Thomas Deller, Tina Stark
Publikováno v:
Analytical Chemistry. 84:5276-5284
In the present work, the recently developed laser-induced liquid bead ion desorption mass spectrometry (LILBID MS) is applied as a novel technique to study Aβ oligomerization, thought to be crucial in Alzheimer's disease (AD). The characterization o
Publikováno v:
ChemInform. 45
Autor:
Maksim Kunitski, Michael W. Göbel, Yevgeniy Nosenko, Pilarisetty Tarakeshwar, Tina Stark, Bernhard Brutschy
Publikováno v:
Physical chemistry chemical physics : PCCP. 15(27)
The vibrational fingerprints of hydrogen-bonding associated with the adenine–thymine (A–T) Watson–Crick (WC) base pair have been identified in an infrared study of the A–T mimics 4-aminopyrimidine–1-methylthymine (4APM–1MT) and 4-aminopyr
Autor:
Tina Stark, Michael W. Göbel, Bernhard Brutschy, Maksim Kunitski, Pilarisetty Tarakeshwar, Yevgeniy Nosenko
Publikováno v:
The journal of physical chemistry. A. 115(41)
We report the infrared spectrum of the 4-aminobenzimidazole-1-methylthymine (4ABI:1MT) heterodimer, detected by femtosecond multiphoton ionization. Based on calculations of both the harmonic and the anharmonic frequencies, the observed vibrational sp