Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tina Sehm"'
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 6, Pp 601-611 (2014)
Most spinal cord injuries lead to permanent paralysis in mammals. By contrast, the remarkable regenerative abilities of salamanders enable full functional recovery even from complete spinal cord transections. The molecular differences underlying this
Externí odkaz:
https://doaj.org/article/391b6918fce04543b472f51a3bba0118
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93264 (2014)
Children and adults with the most aggressive form of brain cancer, malignant gliomas or glioblastoma, often develop cerebral edema as a life-threatening complication. This complication is routinely treated with dexamethasone (DEXA), a steroidal anti-
Externí odkaz:
https://doaj.org/article/78b988b431084341a914461ec9cadb93
Autor:
Tina, Sehm, Ortrud, Uckermann, Roberta, Galli, Matthias, Meinhardt, Elke, Rickelt, Dietmar, Krex, Gabriele, Schackert, Matthias, Kirsch
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Cerebral aneurysms are abnormal focal dilatations of arterial vessel walls with pathological vessel structure alterations. Sudden rupture can lead to a subarachnoid hemorrhage, which is associated with a high mortality. Therefore, the origin of cereb
Autor:
Krista Minéia Wartchow, Andrea Kleindienst, Ali Ghoochani, Michael Buchfelder, Tina Sehm, Justus Baecker
Publikováno v:
Journal of Neurotrauma. 37:1097-1107
Release of neurotrophic and growth factors such as S100 calcium-binding protein B (S100B) yields an endogenous repair mechanism following traumatic brain injury (TBI). Although nanomolar S100B concentrations enhance hippocampal progenitor cell prolif
Autor:
Christian Hartmann, Tina Sehm, Roberta Galli, Ortrud Uckermann, Edmund Koch, Matthias Kirsch, Felix Sahm, Gerald Steiner, Gabriele Schackert, Elke Leipnitz
Publikováno v:
Journal of Biophotonics. 12
Nonlinear multimodal microscopy offers a series of label-free techniques with potential for intraoperative identification of tumor borders in situ using novel endoscopic devices. Here, we combined coherent anti-Stokes Raman scattering, two-photon exc
Autor:
Tina Sehm, Ilker Y. Eyüpoglu, Ali Ghoochani, Zheng Fan, Stefan W. Hock, Michael Buchfelder, Nicolai E. Savaskan, Eduard Yakubov
Publikováno v:
Oncotarget
Primary brain tumors are hallmarked for their destructive activity on the microenvironment and vasculature. However, solely few experimental techniques exist to access the tumor microenvironment under anatomical intact conditions with remaining cellu
Autor:
Tina Sehm, MH Schmidt, Eric P. Meyer, Sebastian Schürmann, NE Savaskan, Marco Stampanoni, I Y Eyüpoglu, Eduard Yakubov, Michael Buchfelder, Oliver Friedrich, Marcus Czabanka, Robert Nitsch, Zheng Fan, ND Stankovic, Thomas Broggini
Brain tumors are among the most malignant primary tumors, hallmarked by angiogenesis, neuronal destruction and brain swelling. Inhibition of the glutamate-cystein antiporter xCT (system xc−/SLC7A11) alleviates seizures, neuronal cell death and tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164a3c65742dfdd66e6ed9edcd671efe
https://doi.org/10.1101/134924
https://doi.org/10.1101/134924
Autor:
Marc, Dahlmanns, Eduard, Yakubov, Daishi, Chen, Tina, Sehm, Manfred, Rauh, Nicolai, Savaskan, Jana Katharina, Wrosch
Publikováno v:
Cell Death Discovery
In the search for new potential chemotherapeutics, the compounds’ toxicity to healthy cells is an important factor. The brain with its functional units, the neurons, is especially endangered during the radio- and chemotherapeutic treatment of brain
Autor:
Ali, Ghoochani, Gökce, Hatipoglu Majernik, Tina, Sehm, Sven, Wach, Michael, Buchfelder, Helge, Taubert, Ilker Y, Eyupoglu, Nicolai, Savaskan
Publikováno v:
Oncotarget
Taxanes target microtubules and are clinically established chemotherapeutic agents with proven efficacy in human cancers. Cabazitaxel (XRP-6258, Jevtana®) is a second generation semisynthetic taxane with high chemotherapeutic potential in prostate c
Autor:
Gökçe, Hatipoglu, Stefan W, Hock, Ruth, Weiss, Zheng, Fan, Tina, Sehm, Ali, Ghoochani, Michael, Buchfelder, Nicolai E, Savaskan, Ilker Y, Eyüpoglu
Publikováno v:
Cancer Science
Malignant gliomas can be counted to the most devastating tumors in humans. Novel therapies do not achieve significant prolonged survival rates. The cancer cells have an impact on the surrounding vital tissue and form tumor zones, which make up the tu