Transient changes in the limbic histaminergic system after systemic kainic acid-induced seizures

Autor: Minnamaija Lintunen, Tina Sallmen, Kaj Karlstedt, Pertti Panula

Publikováno v: Neurobiology of Disease, Vol 20, Iss 1, Pp 155-169 (2005)

Increased brain histamine is reported to protect against convulsions. We used systemic kainic acid (KA) administration to study possible changes of the histaminergic system in rat brain in status epilepticus (SE). Robust increases in brain histamine

Externí odkaz: https://doaj.org/article/09a74b6bc35d4e67af9136d1cd8fa131

Myocyte Enhancer Factor 2C as a Neurogenic and Antiapoptotic Transcription Factor in Murine Embryonic Stem Cells

Autor: Jeffrey H. Lipton, Zhen Li, Jiankun Cui, Tina Sallmen, Walid Soussou, Zhiguo Nie, Shu-ichi Okamoto, Maria Talantova, Amanda J. Roberts, Scott R. McKercher, Stuart A. Lipton

Publikováno v: Journal of Neuroscience. 28:6557-6568

Cell-based therapies require a reliable source of cells that can be easily grown, undergo directed differentiation, and remain viable after transplantation. Here, we generated stably transformed murine ES (embryonic stem) cells that express a constit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba1ec51855495183d36e9b4b69380c3
https://doi.org/10.1523/jneurosci.0134-08.2008

The histaminergic system in the brain: structural characteristics and changes in hibernation

Autor: Kimmo A. Michelsen, Minnamaija Lintunen, Pertti Panula, Oleg Anichtchik, Jan Kaslin, Nina Peitsaro, Tina Sallmen, Kaj Karlstedt, T.-K. Kukko-Lukjanov

Publikováno v: Journal of Chemical Neuroanatomy. 18:65-74

Histaminergic neurons in adult vertebrate brain are confined to the posterior hypothalamic area, where they are comprised of scattered groups of neurons referred to as the tuberomammillary nucleus. Histamine regulates hormonal functions, sleep, food

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2133adfacbdf9697f1d6a2b62e17c87f
https://doi.org/10.1016/s0891-0618(99)00052-6

Lack of Histamine Synthesis and Down-Regulation of H1 and H2 Receptor mRNA Levels by Dexamethasone in Cerebral Endothelial Cells

Autor: Minnamaija Lintunen, Ferenc Joó, Kaj Karlstedt, Krister Eriksson, Pertti Panula, Pierre-Olivier Couraud, Tina Sallmen

Publikováno v: Journal of Cerebral Blood Flow & Metabolism. 19:321-330

The purpose of this work was to determine whether cerebral endothelial cells have the capacity to synthesize histamine or to express mRNA of receptors that specifically respond to available free histamine. The histamine concentrations and the express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33355c57bd5ddcbfca201f8e5b5fe69d
https://doi.org/10.1097/00004647-199903000-00010

Increased brain histamine in an alcohol-preferring rat line and modulation of ethanol consumption by H3 receptor mechanisms

Autor: Minnamaija Lintunen, Leena Tuomisto, Rob Leurs, Esa R. Korpi, Kaj Karlstedt, Petri Hyytiä, Kalervo Kiianmaa, Tina Sallmen, Pertti Panula

Publikováno v: FASEB Journal, 15(6), 1074-6. FASEB
Lintunen, M, Hyytia, P, Sallmen, T, Karlstedt, K, Tuomisto, L, Leurs, R, Kiianmaa, K, Korpi, E R & Panula, P 2001, ' Increased brain histamine in an alcohol-preferring rat line and modulation of ethanol consumption by H(3) receptor mechanisms ', FASEB Journal, vol. 15, no. 6, pp. 1074-6 . https://doi.org/10.1096/fj.00-0545fje

SPECIFIC AIMIt has been suggested that the histaminergic system regulates brain reward mechanisms, the molecular basis of which is poorly understood. By applying molecular and behavioral methods to...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c79c5c161c78351eafc83a563d6f54
https://doi.org/10.1096/fj.00-0545fje