Zobrazeno 1 - 1
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pro vyhledávání: '"Tina S Bisgaard"'
Autor:
Marco Berrera, Marianne Lerbech Jensen, Martin Ebeling, Peter Hagedorn, Marianne R. Møller, Morten Lindow, Troels Koch, Henrik Frydenlund Hansen, Malene Pontoppidan, Heidi Rye Hudlebusch, Andreas Dieckmann, Tina S Bisgaard
Publikováno v:
Nucleic Acids Research
Hagedorn, P H, Pontoppidan, M, Bisgaard, T S, Berrera, M, Dieckmann, A, Ebeling, M, Møller, M R, Hudlebusch, H, Jensen, M L, Hansen, H F, Koch, T & Lindow, M 2018, ' Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice ', Nucleic Acids Research, vol. 46, no. 11, pp. 5366-5380 . https://doi.org/10.1093/nar/gky397
Hagedorn, P H, Pontoppidan, M, Bisgaard, T S, Berrera, M, Dieckmann, A, Ebeling, M, Møller, M R, Hudlebusch, H, Jensen, M L, Hansen, H F, Koch, T & Lindow, M 2018, ' Identifying and avoiding off-target effects of RNase H-dependent antisense oligonucleotides in mice ', Nucleic Acids Research, vol. 46, no. 11, pp. 5366-5380 . https://doi.org/10.1093/nar/gky397
Antisense oligonucleotides that are dependent on RNase H for cleavage and subsequent degradation of complementary RNA are being developed as therapeutics. Besides the intended RNA target, such oligonucleotides may also cause degradation of unintended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5852a56ae13fabda0113b0fcc3dafeb6
https://doi.org/10.1093/nar/gky397
https://doi.org/10.1093/nar/gky397
