Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tina Robinson"'
Autor:
Anna Konopka, Donna R. Whelan, Md Shafi Jamali, Emma Perri, Hamideh Shahheydari, Reka P. Toth, Sonam Parakh, Tina Robinson, Alison Cheong, Prachi Mehta, Marta Vidal, Audrey M. G. Ragagnin, Ivan Khizhnyak, Cyril J. Jagaraj, Jasmin Galper, Natalie Grima, Anand Deva, Sina Shadfar, Garth A. Nicholson, Shu Yang, Suzanne M. Cutts, Zuzana Horejsi, Toby D. M. Bell, Adam K. Walker, Ian P. Blair, Julie D. Atkin
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-28 (2020)
Abstract Background Pathological forms of TAR DNA-binding protein 43 (TDP-43) are present in motor neurons of almost all amyotrophic lateral sclerosis (ALS) patients, and mutations in TDP-43 are also present in ALS. Loss and gain of TDP-43 functions
Externí odkaz:
https://doaj.org/article/3003b649896947f29c746f302d459637
Autor:
Damien J Zanker, Alex J Spurling, Natasha K Brockwell, Katie L Owen, Jasmine M Zakhour, Tina Robinson, Hendrika M Duivenvoorden, Paul J Hertzog, Stefanie R Mullins, Robert W Wilkinson, Belinda S Parker
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 9, Pp n/a-n/a (2020)
Abstract Objectives Loss of tumor‐inherent type I interferon (IFN) signalling has been closely linked to accelerated metastatic progression via decreased immunogenicity and antitumor immunity. Previous studies in murine models of triple‐negative
Externí odkaz:
https://doaj.org/article/61578605bee846698ae1d74398aee779
Publikováno v:
Laboratory Animals. 55:367-374
NSG™ mice are highly immunocompromised thus demonstrate high efficiency engraftment of patient-derived xenografts (PDXs) for pre-clinical oncology research. It has previously been reported that NSG™ mice are hyper-sensitive to doxorubicin due to
Autor:
Alison Cheong, Sonam Parakh, Sina Shadfar, Prachi Mehta, Shu Yang, Anand K. Deva, Anna Konopka, Natalie Grima, Adam K. Walker, Cyril J. Jagaraj, Emma R. Perri, Suzanne M. Cutts, Tina Robinson, Garth A. Nicholson, Hamideh Shahheydari, Reka P. Toth, Shafi Jamali, Julie D. Atkin, Audrey Ragagnin, Ian P. Blair, Toby D. M. Bell, Zuzana Horejsi, Marta Vidal, Ivan Khizhnyak, Donna R. Whelan, Jasmin Galper
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-28 (2020)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Pathological forms of TAR DNA-binding protein 43 (TDP-43) are present in motor neurons of almost all amyotrophic lateral sclerosis (ALS) patients, and mutations in TDP-43 are also present in ALS. Loss and gain of TDP-43 functions are impli
Autor:
Corinne Ooi, Alex Spurling, Jane Fox, Vinod Ganju, Linden J. Gearing, Michelle White, Beena Kumar, Damien Zanker, Timothy J. Molloy, Hendrika M. Duivenvoorden, Helen E. Cumming, Jasmine M. Zakhour, Kate Harvey, Siddhartha Deb, Tina Robinson, Marion Harris, Paul J. Hertzog, Natasha K Brockwell, Jai Rautela, Sandra O’ Toole, Jacqui Thomson, Chia-Ling Chan, Niantao Deng, Belinda S. Parker, Katie L. Owen, Alexander Swarbrick, Nicole Potasz
Publikováno v:
npj Precision Oncology, Vol 3, Iss 1, Pp 1-13 (2019)
NPJ Precision Oncology
NPJ Precision Oncology
Patients diagnosed with triple negative breast cancer (TNBC) have an increased risk of rapid metastasis compared to other subtypes. Predicting long-term survival post-chemotherapy in patients with TNBC is difficult, yet enhanced infiltration of tumor
Autor:
Robert W. Wilkinson, Hendrika M. Duivenvoorden, Damien Zanker, Alex J. Spurling, Stefanie R. Mullins, Belinda S. Parker, Tina Robinson, Natasha K Brockwell, Katie L. Owen, Paul J. Hertzog, Jasmine M. Zakhour
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 9, Pp n/a-n/a (2020)
Clinical & Translational Immunology
Clinical & Translational Immunology
Objectives Loss of tumor‐inherent type I interferon (IFN) signalling has been closely linked to accelerated metastatic progression via decreased immunogenicity and antitumor immunity. Previous studies in murine models of triple‐negative breast ca
Autor:
Salvatore Pepe, Alison Cheong, Tina Robinson, Ada Rephaeli, Ruqaya Maliki, Abraham Nudelman, Donald R. Phillips, Alex J. Spurling, Suzanne Margaret Cutts, Sean McGrath, Belinda S. Parker
Publikováno v:
Cancer Research. 81:992-992
Chemotherapy remains as the mainstay systemic therapy for triple negative breast cancer patients since targeted therapies are not suitable for this breast cancer subtype. Among the chemotherapies for triple negative breast cancer, doxorubicin is know
Autor:
Abraham Nudelman, Sean McGrath, Belinda S. Parker, Ada Rephaeli, Alison Cheong, Peter Lock, Salvatore Pepe, Tina Robinson, Alex Spurling, Suzanne M. Cutts, Ruqaya Maliki
Publikováno v:
Biochemical Pharmacology. 185:114410
Cancer patients treated with doxorubicin are at risk of congestive heart failure due to doxorubicin-mediated cardiotoxicity via topoisomerase IIβ poisoning. Acute cardiac muscle damage occurs in response to the very first dose of doxorubicin, howeve
Publikováno v:
Adultspan Journal. 14:24-34
Women with attention-deficit/hyperactivity disorder (ADHD) often struggle with the developmental challenges of adulthood and ADHD-related problems. The authors provide specific clinical interventions from a narrative-based group approach to help wome
Autor:
Suzanne M. Cutts, Anthony I. Day, Alison Cheong, Lynne Wallace, Sean McGrath, Tina Robinson, Peter Lock, Don R. Phillips, Alex Spurling, Belinda S. Parker, Shyam K. Konda, Ruqaya Maliki, J. Grant Collins, Paul J. Pigram
Mitoxantrone was efficiently encapsulated within cucurbit[8]uril in a 2:1 complex where the two mitoxantrone molecules were symmetrically located through both portals of a cucurbit[8]uril cage. The novel complex facilitates increased mitoxantrone upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fb5bf870310b26517cd4f97e943486
https://europepmc.org/articles/PMC5430389/
https://europepmc.org/articles/PMC5430389/