Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tina Perica"'
Autor:
Danielle L. Swaney, Christopher J.P. Mathy, Nevan J. Krogan, Tina Perica, Hannes Braberg, Yang Zhang, Noah Ollikainen, David G. Lambright, Tanja Kortemme, Jiewei Xu, Robyn M. Kaake, Gwendolyn Μ. Jang, Mark J. S. Kelly
Publikováno v:
Nature. 599:152-157
Molecular switch proteins whose cycling between states is controlled by opposing regulators1,2 are central to biological signal transduction. As switch proteins function within highly connected interaction networks3, the fundamental question arises o
Autor:
Christopher J.P. Mathy, Parul Mishra, Julia M. Flynn, Tina Perica, David Mavor, Daniel N.A. Bolon, Tanja Kortemme
Allosteric regulation is central to protein function in cellular networks1. However, despite technological advances2,3 most studies of allosteric effects on function are conducted in heterologous environments2,4,5, limiting the discovery of allosteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5e98ca0ccc901d8927ed882a7649a4
https://doi.org/10.1101/2022.04.13.488230
https://doi.org/10.1101/2022.04.13.488230
Autor:
Pedro Beltrao, Phillip P. Sharp, Nevan J. Krogan, Sabrina J. Fletcher, Saker Klippsten, Trey Ideker, Melanie Ott, Bryan L. Roth, Xi Liu, Devin A. Cavero, Djoshkun Shengjuler, Christopher J.P. Mathy, Jason C.J. Chang, Theodore L. Roth, Hannes Braberg, Claudia Hernandez-Armenta, Lisa Miorin, Jyoti Batra, Shizhong Dai, Maliheh Safari, Brian K. Shoichet, Danish Memon, Tia A. Tummino, Marco Vignuzzi, Mark von Zastrow, Manon Eckhardt, Alan D. Frankel, Qiongyu Li, Tanja Kortemme, Nicole A. Wenzell, Zun Zar Chi Naing, Ferdinand Roesch, Nastaran Sadat Savar, Mathieu Hubert, Xi Ping Huang, Elena Moreno, Danica Galonić Fujimori, Jeffrey Z. Guo, Natalia Jura, Kirsten Obernier, Kliment A. Verba, Harmit S. Malik, Hao-Yuan Wang, Michael McGregor, Melanie J. Bennett, Julia Noack, Gwendolyn M. Jang, Paige Haas, Alice Mac Kain, Daniel J. Saltzberg, Mehdi Bouhaddou, Ziyang Zhang, Yongfeng Liu, Inigo Barrio-Hernandez, Yiming Cai, Kris M. White, Kelsey M. Haas, Maya Modak, Stephanie A. Wankowicz, Raphael Trenker, Kevan M. Shokat, Fatima S. Ugur, Shiming Peng, Sai J. Ganesan, Shaeri Mukherjee, Yuan Zhou, Minkyu Kim, John D. Gross, Jack Taunton, Alicia L. Richards, John S. Chorba, Margaret Soucheray, Danielle L. Swaney, Benjamin J. Polacco, Alan Ashworth, Wenqi Shen, Adolfo García-Sastre, Merve Cakir, Ujjwal Rathore, Kala Bharath Pilla, Michael C. O’Neal, Ying Shi, Kevin Lou, Cassandra Koh, Stephen N. Floor, Davide Ruggero, Ilsa T Kirby, Srivats Venkataramanan, Ruth Hüttenhain, Olivier Schwartz, Beril Tutuncuoglu, Christophe d'Enfert, Jose Liboy-Lugo, David A. Agard, Charles S. Craik, Veronica V. Rezelj, Tina Perica, Matthew P. Jacobson, Lorenzo Calviello, Eric Verdin, Yizhu Lin, Jiankun Lyu, Jiewei Xu, Joseph Hiatt, Andrej Sali, Oren S. Rosenberg, Markus Bohn, David E. Gordon, James S. Fraser, Sara Brin Rosenthal, Duygu Kuzuoğlu-Öztürk, Robyn M. Kaake, Jacqueline M. Fabius, Matthew J. O’Meara, Quang Dinh Tran, Advait Subramanian, Thomas Vallet, Bjoern Meyer, James E. Melnyk, Robert M. Stroud, Helene Foussard, Rakesh Ramachandran, David J. Broadhurst, Janet M. Young, Michael Emerman
Publikováno v:
Nature
Schizophrenia Research
Schizophrenia Research
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led to the death of more than 160,000 individ
Autor:
David E. Gordon, Gwendolyn M. Jang, Qiongyu Li, Natalia Jura, Sara Brin Rosenthal, Trey Ideker, Paige Haas, Melanie J. Bennett, Ilsa T Kirby, Adolfo García-Sastre, Michael Emerman, Thomas Vallet, Tina Perica, Lorenzo Calviello, Kirsten Obernier, Kliment A. Verba, Tanja Kortemme, Michael McGregor, Alan Ashworth, Ujjwal Rathore, Ziyang Zhang, Kelsey M. Haas, Rakesh Ramachandran, Mark von Zastrow, Jacqueline M. Fabius, Theodore L. Roth, Daniel J. Saltzberg, Matthew P. Jacobson, Kevin Lou, Ferdinand Roesch, Yizhu Lin, John S. Chorba, Beril Tutuncuoglu, Claudia Hernandez-Armenta, Harmit S. Malik, Janet M. Young, Manon Eckhardt, Srivats Venkataramanan, Jose Liboy-Lugo, Phillip P. Sharp, Jeffrey Z. Guo, Maya Modak, Shaeri Mukherjee, Markus Bohn, Brian K. Shoichet, Olivier Schwartz, Jiewei Xu, James S. Fraser, Andrej Sali, Oren S. Rosenberg, Christopher J.P. Mathy, Charles S. Craik, Benjamin J. Polacco, Melanie Ott, Sai J. Ganesan, Pedro Beltrao, Alicia L. Richards, Helene Foussard, Margaret Soucheray, Joseph Hiatt, Robyn M. Kaake, Danielle L. Swaney, Wenqi Shen, Bjoern Meyer, Kala Bharath Pilla, Zun Zar Chi Naing, Marco Vignuzzi, James E. Melnyk, John D. Gross, Shiming Peng, Mehdi Bouhaddou, Nevan J. Krogan, Merve Cakir, Mathieu Hubert, Stephanie A. Wankowicz, Ying Shi, Davide Ruggero, Kevan M. Shokat, Stephen N. Floor, Jack Taunton, Xi Liu, Ruth Hüttenhain, David A. Agard, Lisa Miorin, Danish Memon, Julia Noack, Raphael Trenker, Hannes Braberg, Shizhong Dai, Tia A. Tummino, Kris M. White, Yuan Zhou, Minkyu Kim, Devin A. Cavero, Jyoti Batra, Advait Subramanian, Danica Galonić Fujimori, Inigo Barrio-Hernandez
Publikováno v:
bioRxiv : the preprint server for biology, vol 1, iss 05-20
bioRxiv
article-version (status) pre
article-version (number) 1
bioRxiv
article-version (status) pre
article-version (number) 1
Author(s): Gordon, David E; Jang, Gwendolyn M; Bouhaddou, Mehdi; Xu, Jiewei; Obernier, Kirsten; O'Meara, Matthew J; Guo, Jeffrey Z; Swaney, Danielle L; Tummino, Tia A; Huttenhain, Ruth; Kaake, Robyn M; Richards, Alicia L; Tutuncuoglu, Beril; Foussard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8186932c52fbde3f27787d30adc7ec
https://escholarship.org/uc/item/9v71w6zc
https://escholarship.org/uc/item/9v71w6zc
Autor:
Gwendolyn M. Jang, Hannes Braberg, Jiewei Xu, Tina Perica, Christopher J.P. Mathy, Robyn M. Kaake, Mark J. S. Kelly, Yang Zhang, Nevan J. Krogan, Tanja Kortemme, David G. Lambright, Noah Ollikainen, Danielle L. Swaney
Molecular switches are central to signal transduction in protein interaction networks. One switch protein can independently regulate distinct cellular processes, but the molecular mechanisms enabling this functional multi-specificity remain unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d48dbb7f27171827db6f37f8adcc38
https://doi.org/10.1101/2020.01.04.893909
https://doi.org/10.1101/2020.01.04.893909
Autor:
Tina, Perica, Christopher J P, Mathy, Jiewei, Xu, Gwendolyn Μ, Jang, Yang, Zhang, Robyn, Kaake, Noah, Ollikainen, Hannes, Braberg, Danielle L, Swaney, David G, Lambright, Mark J S, Kelly, Nevan J, Krogan, Tanja, Kortemme
Publikováno v:
Trends Biochem Sci
GTPase switches are hubs for multiple distinct cell signaling inputs and outputs. In a new study combining genetic and biochemical methods, Perica & Mathy et al. identify an unexpected connection between the kinetics of a GTPase switch cycle and func
Publikováno v:
Current Opinion in Structural Biology. 23:954-963
Here we review mechanisms of protein evolution leading to structural changes in protein complexes. These mechanisms include mutations directly within protein interfaces, as well as the effects of mutations that propagate from distant regions of the p
Autor:
Tina Perica, Joseph A. Marsh, Filipa L. Sousa, Sarah A. Teichmann, Eviatar Natan, Lucy J. Colwell, Sebastian E. Ahnert
Publikováno v:
Biochemical Society Transactions. 40:475-491
All proteins require physical interactions with other proteins in order to perform their functions. Most of them oligomerize into homomers, and a vast majority of these homomers interact with other proteins, at least part of the time, forming transie
Publikováno v:
Proceedings of the National Academy of Sciences. 109:8127-8132
Oligomerization plays an important role in the function of many proteins. Thus, understanding, predicting, and, ultimately, engineering oligomerization presents a long-standing interest. From the perspective of structural biology, protein–protein i
Autor:
Yasushi Kondo, Jane Clarke, Tina Perica, Xiuwei Zhang, Annette Steward, Sarah A. Teichmann, Sandhya Premnath Tiwari, Katherine R. Kemplen, Nathalie Reuter, Stephen H. McLaughlin
Publikováno v:
Science
Introduction Evolution and design of protein complexes are frequently viewed through the lens of amino acid mutations at protein interfaces, but we showed previously that residues distant from interfaces are also commonly involved in the evolution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7797c99d360d60eb5e5090d08e429b7c
https://www.repository.cam.ac.uk/handle/1810/246409
https://www.repository.cam.ac.uk/handle/1810/246409