Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tina P. Tran"'
Autor:
Sasha L. Fulton, Wendy Wenderski, Ashley E. Lepack, Andrew L. Eagle, Tomas Fanutza, Ryan M. Bastle, Aarthi Ramakrishnan, Emma C. Hays, Arianna Neal, Jaroslav Bendl, Lorna A. Farrelly, Amni Al-Kachak, Yang Lyu, Bulent Cetin, Jennifer C. Chan, Tina N. Tran, Rachael L. Neve, Randall J. Roper, Kristen J. Brennand, Panos Roussos, John C. Schimenti, Allyson K. Friedman, Li Shen, Robert D. Blitzer, Alfred J. Robison, Gerald R. Crabtree, Ian Maze
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The molecular mechanisms underlying deficits in Down syndrome remain unclear. Here, the authors show that copy number restoration of a chromatin remodeler in trisomic mice is sufficient to rescue epigenomic, physiological and cognitive deficits.
Externí odkaz:
https://doaj.org/article/4d9fc438d0e34047a77c7e2c58308fbb
Autor:
Priti Singh, Robert Fragoza, Cecilia S. Blengini, Tina N. Tran, Gianno Pannafino, Najla Al-Sweel, Kerry J. Schimenti, Karen Schindler, Eric A. Alani, Haiyuan Yu, John C. Schimenti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Proper meiotic chromosome segregation requires mismatch repair genes MLH1 and MLH3, of which variants occur in the human population. Here, the authors use computational predictions and yeast assays to select human MLH1/3 variants for modelling in mic
Externí odkaz:
https://doaj.org/article/ea5df12e8dcb4fb3a1ae13ed6a79b628
Autor:
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Low frequency coding single-nucleotide variants (SNVs) are predicted to disproportionately affect protein function. Here, the authors evaluate 2,009 missense SNVs across 2,185 protein-protein interactions using yeast two-hybrid and protein complement
Externí odkaz:
https://doaj.org/article/6ca43b750ead45778c9bbf8306bf1546
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48725 (2012)
ATP is an important modulator of gating in type 1 ryanodine receptor (RyR1), also known as a Ca²⁺ release channel in skeletal muscle cells. The activating effect of ATP on this channel is achieved by directly binding to one or more sites on the Ry
Externí odkaz:
https://doaj.org/article/9f3324c276e34600a2d0469390fbf8b1
Autor:
Tina P. Tran, Adaora M. Chima, Eric V. Jackson, Megan K. Marx, Benjamin H. Lee, Onyebuchi Ogbuagu, Michael Koroma, Rahul Koka, John Sampson, Michael A. Rosen
Publikováno v:
Anesthesia & Analgesia. 123:213-227
Background Anesthesia in West Africa is associated with high mortality rates. Critical shortages of adequately trained personnel, unreliable electrical supply, and lack of basic monitoring equipment are a few of the unique challenges to surgical care
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3597565d0dadd010e46c397f3169a44
https://doi.org/10.1213/ane.0000000000001285
https://doi.org/10.1213/ane.0000000000001285
Autor:
Benjamin H. Lee, Adaora M. Chima, Eric V. Jackson, Rahul Koka, Tina P. Tran, Onyebuchi O. Ogbuagu, John Sampson, Michael A. Rosen
Publikováno v:
Journal of the National Medical Association. 111(5)
Background Anesthesia providers in low- and middle-income countries face many challenges, including poor availability of functioning equipment designed to meet their environmental, organizational, and resource constraints. These are serious global he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed2388d6fb49143666696d8cf8fba50
https://pubmed.ncbi.nlm.nih.gov/31078287
https://pubmed.ncbi.nlm.nih.gov/31078287
Publikováno v:
Cancer Causes and Control. 13:675-682
Objective: The importance of p16 alterations in the pathogenesis of dysplastic nevi and sporadic melanoma remains controversial. The goal of this work was to discover if p16/9p21 alterations occur early in precursor lesions as well as related sporadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbe6c9612752f77874486a212a6aef76
https://doi.org/10.1023/a:1019599629895
https://doi.org/10.1023/a:1019599629895
Publikováno v:
PLoS ONE
ATP is an important modulator of gating in type 1 ryanodine receptor (RyR1), also known as a Ca²⁺ release channel in skeletal muscle cells. The activating effect of ATP on this channel is achieved by directly binding to one or more sites on the Ry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ffa7e5757b768b705bdde589913c11
http://europepmc.org/articles/PMC3492408
http://europepmc.org/articles/PMC3492408
Publikováno v:
Cancer causescontrol : CCC. 13(7)
The importance of p16 alterations in the pathogenesis of dysplastic nevi and sporadic melanoma remains controversial. The goal of this work was to discover if p16/9p21 alterations occur early in precursor lesions as well as related sporadic melanomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c485625377b6f86cc02fa02bced46c8
https://pubmed.ncbi.nlm.nih.gov/12296515
https://pubmed.ncbi.nlm.nih.gov/12296515
Publikováno v:
Biophysical Journal. (3):305a
Adenine nucleotides are basic modulators of Ca2+ release channels from sarcoplasmic reticulum, ryanodine receptors (RyRs). Similar to several other ion channels, ATP acts as a non-hydrolyzed ligand for activation of RyR1 with EC50 in the millimolar r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4091a0e9f34bf0b3c5bccf8263c9eac5