Zobrazeno 1 - 5
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pro vyhledávání: '"Tina M. Davis"'
Publikováno v:
European Journal of Organic Chemistry. 2002:1077-1084
The mechanism of the unique destabilization of a folded RNA by the azoniacyclophane CP66 has been investigated by complexation studies with mono- and short single-stranded oligonucleotides as models. For the mononucleotides, NMR titrations revealed o
Publikováno v:
Biochemistry. 40:1150-1158
As part of a search for organic compounds that selectively target RNA, we found that specific diphenylfuran derivatives, which are related to compounds that bind to the DNA minor groove, bind very strongly to RNA in a manner very sensitive to the str
Autor:
David W. Boykin, Arvind Kumar, Ge Xiao, Ke Li, C.Ted Rigl, Miroslav Bajić, W. David Wilson, Tina M. Davis
Publikováno v:
Bioorganicmedicinal chemistry. 9(5)
RNA viruses cause a wide range of human diseases. Development of new agents to target such viruses is an active area of research. Towards this goal, a series of diphenylfuran cations as potential inhibitors of the Rev-RRE complex have been designed a
Publikováno v:
Biochemistry. 37(19)
UV absorbance spectroscopy is the most common method for detecting nucleic acid structural transitions and obtaining thermodynamic parameters. UV-detected melting has been used to determine stabilities of nucleic acid hairpins, duplexes, triplexes, a
Publikováno v:
The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses. 27(1)
Two to three million people in this country live with the after-effects of a stroke. Care focuses on increasing the functional abilities of the stroke patient. Currently, there are different approaches used in caring for the stroke patient. Two appro