Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Tina M Calderon"'
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117450 (2015)
Drug abuse is a major comorbidity of HIV infection and cognitive disorders are often more severe in the drug abusing HIV infected population. CD14+CD16+ monocytes, a mature subpopulation of peripheral blood monocytes, are key mediators of HIV neuropa
Externí odkaz:
https://doaj.org/article/3fecb8c2b2ec4e98a3dd480e4aeafcbb
Autor:
Dionna W Williams, Tina M Calderon, Lillie Lopez, Loreto Carvallo-Torres, Peter J Gaskill, Eliseo A Eugenin, Susan Morgello, Joan W Berman
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69270 (2013)
As HIV infected individuals live longer, the prevalence of HIV associated neurocognitive disorders is increasing, despite successful antiretroviral therapy. CD14(+)CD16(+) monocytes are critical to the neuropathogenesis of HIV as they promote viral s
Externí odkaz:
https://doaj.org/article/1c740ff7ec6c4bf1b3a3f74251cb4af9
Autor:
Vanessa Chilunda, Pablo Martinez-Aguado, Li C. Xia, Laura Cheney, Aniella Murphy, Veronica Veksler, Vanessa Ruiz, Tina M. Calderon, Joan W. Berman
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
The COVID-19 pandemic has caused more than three million deaths globally. The severity of the disease is characterized, in part, by a dysregulated immune response. CD16+ monocytes are innate immune cells involved in inflammatory responses to viral in
Autor:
Korhan Buyukturkoglu, Lucio Gama, Lazar Fleysher, Joan W. Berman, Susan Morgello, Mike Veenstra, Rosiris León-Rivera, Matilde Inglese, Ming Li, Janice E. Clements, Desiree Byrd, Tina M. Calderon, Dionna W. Williams
Publikováno v:
Journal of Neuroimmune Pharmacology. 14:120-133
HIV-associated neurocognitive disorders (HAND) occur in ~50% of HIV infected individuals despite combined antiretroviral therapy. Transmigration into the CNS of CD14(+)CD16(+) monocytes, particularly those that are HIV infected and express increased
Publikováno v:
J Neuroimmune Pharmacol
Antiretroviral therapy (ART) has transformed HIV into a chronic condition, lengthening and improving the lives of individuals living with this virus. Despite successful suppression of HIV replication, people living with HIV (PLWH) are susceptible to
Autor:
Mike Veenstra, Kathryn Anastos, Susan Morgello, Dionna W. Williams, Tina M. Calderon, Joan W. Berman
Publikováno v:
Journal of Leukocyte Biology. 102:1173-1185
CD14+CD16+ monocytes transmigrate into the CNS of HIV-positive people in response to chemokines elevated in the brains of infected individuals, including CXCL12. Entry of these cells leads to viral reservoirs, neuroinflammation, and neuronal damage.
Autor:
Mike Veenstra, Peter J. Gaskill, Dionna W. Williams, Eliseo A. Eugenin, Kathryn Anastos, Laura Cheney, Tina M. Calderon, Joan W. Berman, Lillie Lopez, Susan Morgello
Publikováno v:
Journal of Neuroimmune Pharmacology. 12:353-370
In human immunodeficiency virus-1 (HIV) infected individuals, substance abuse may accelerate the development and/or increase the severity of HIV associated neurocognitive disorders (HAND). It is proposed that CD14+CD16+ monocytes mediate HIV entry in
Publikováno v:
Brain Res
Approximately 37 million people worldwide are infected with human immunodeficiency virus (HIV). One highly significant complication of HIV infection is the development of HIV-associated neurocognitive disorders (HAND) in 15–55% of people living wit
Autor:
Ruth Hogue Angeletti, Fa Yun Che, Tina M. Calderon, Lillie Lopez, Andras Fiser, Jihyeon Lim, Edward Nieves, Carlos J. Madrid-Aliste, Loreto Carvallo, Dionna W. Williams, Joan W. Berman, Louis M. Weiss, Eliseo A. Eugenin
Publikováno v:
The Journal of Immunology. 194:3246-3258
Despite successful combined antiretroviral therapy, ∼60% of HIV-infected people exhibit HIV-associated neurocognitive disorders (HAND). CCL2 is elevated in the CNS of infected people with HAND and mediates monocyte influx into the CNS, which is cri
Publikováno v:
Journal of Leukocyte Biology. 91:401-415
HIV continues to be a global health crisis with more than 34 million people infected worldwide (UNAIDS: Report on the Global AIDS Epidemic 2010, Geneva, World Health Organization). HIV enters the CNS within 2 weeks of infection and establishes a spec