Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Tina L Tootle"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Introduction: A key regulator of collective cell migration is prostaglandin (PG) signaling. However, it remains largely unclear whether PGs act within the migratory cells or their microenvironment to promote migration. Here we use Drosophila border c
Externí odkaz:
https://doaj.org/article/9c8235328d9b4692886aeb81b6b7c311
Autor:
Danielle E. Talbot, Bailey J. Vormezeele, Garrett C. Kimble, Dylane M. Wineland, Daniel J. Kelpsch, Michelle S. Giedt, Tina L. Tootle
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Prostaglandins (PGs), locally acting lipid signals, regulate female reproduction, including oocyte development. However, the cellular mechanisms of PG action remain largely unknown. One cellular target of PG signaling is the nucleolus. Indeed, across
Externí odkaz:
https://doaj.org/article/2ea295a7aaa44f3c87517c5a8850bede
Autor:
Maureen C Lamb, Chathuri P Kaluarachchi, Thiranjeewa I Lansakara, Samuel Q Mellentine, Yiling Lan, Alexei V Tivanski, Tina L Tootle
Publikováno v:
eLife, Vol 10 (2021)
A key regulator of collective cell migrations, which drive development and cancer metastasis, is substrate stiffness. Increased substrate stiffness promotes migration and is controlled by Myosin. Using Drosophila border cell migration as a model of c
Externí odkaz:
https://doaj.org/article/710d2b662d4c4d41bf665362766d6c6e
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3555-3565 (2019)
Prostaglandins (PGs) are lipid signaling molecules with numerous physiologic functions, including pain/inflammation, fertility, and cancer. PGs are produced downstream of cyclooxygenase (COX) enzymes, the targets of non-steroidal anti-inflammatory dr
Externí odkaz:
https://doaj.org/article/77b2c94c8a6748f69c766b2ef2b6446e
Autor:
Michelle S. Giedt, Jonathon M. Thomalla, Roger P. White, Matthew R. Johnson, Zon Weng Lai, Tina L. Tootle, Michael A. Welte
Publikováno v:
Development.
Lipid droplets (LDs), crucial regulators of lipid metabolism, accumulate during oocyte development. However, their roles in fertility remain largely unknown. During Drosophila oogenesis, LD accumulation coincides with actin remodeling necessary for f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23db70a58972130acf38c8e35344f417
https://doi.org/10.1242/dev.201516
https://doi.org/10.1242/dev.201516
Autor:
Michelle S. Giedt, Tina L. Tootle
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629697
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dfad7509314bd8a11af3612829017c1
https://doi.org/10.1007/978-1-0716-2970-3_1
https://doi.org/10.1007/978-1-0716-2970-3_1
Autor:
Maureen C. Lamb, Tina L. Tootle
Publikováno v:
Biology, Vol 9, Iss 11, p 403 (2020)
Fascin, an actin-binding protein, regulates many developmental migrations and contributes to cancer metastasis. Specifically, Fascin promotes cell motility, invasion, and adhesion by forming filopodia and invadopodia through its canonical actin bundl
Externí odkaz:
https://doaj.org/article/36a3bd97e755477492ad0844d30b3aa6
Publikováno v:
eLS. :958-967
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b63cc5fb68eb0cc9735c3ec658fd3f1
https://doi.org/10.1002/9780470015902.a0028471
https://doi.org/10.1002/9780470015902.a0028471
Fascin regulates protrusions and delamination to mediate invasive, collective cell migration in vivo
Publikováno v:
Dev Dyn
BACKGROUND: The actin bundling protein Fascin is essential for developmental cell migrations and promotes cancer metastasis. In addition to bundling actin, Fascin has several actin-independent roles; how these other functions contribute to cell migra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b1adf6ae1ab9d9e1b021a29756394f
https://doi.org/10.1002/dvdy.186
https://doi.org/10.1002/dvdy.186
Autor:
Alexei V. Tivanski, Tina L. Tootle, Maureen C. Lamb, Samuel Q Mellentine, Thiranjeewa I. Lansakara, Yiling Lan, Chathuri P. Kaluarachchi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e2f9e1be52b6e80c40ea0bd9c1bd72e
https://doi.org/10.7554/elife.69836.sa2
https://doi.org/10.7554/elife.69836.sa2