Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

Autor: Paul S de Vries, Maria Sabater-Lleal, Daniel I Chasman, Stella Trompet, Tarunveer S Ahluwalia, Alexander Teumer, Marcus E Kleber, Ming-Huei Chen, Jie Jin Wang, John R Attia, Riccardo E Marioni, Maristella Steri, Lu-Chen Weng, Rene Pool, Vera Grossmann, Jennifer A Brody, Cristina Venturini, Toshiko Tanaka, Lynda M Rose, Christopher Oldmeadow, Johanna Mazur, Saonli Basu, Mattias Frånberg, Qiong Yang, Symen Ligthart, Jouke J Hottenga, Ann Rumley, Antonella Mulas, Anton J M de Craen, Anne Grotevendt, Kent D Taylor, Graciela E Delgado, Annette Kifley, Lorna M Lopez, Tina L Berentzen, Massimo Mangino, Stefania Bandinelli, Alanna C Morrison, Anders Hamsten, Geoffrey Tofler, Moniek P M de Maat, Harmen H M Draisma, Gordon D Lowe, Magdalena Zoledziewska, Naveed Sattar, Karl J Lackner, Uwe Völker, Barbara McKnight, Jie Huang, Elizabeth G Holliday, Mark A McEvoy, John M Starr, Pirro G Hysi, Dena G Hernandez, Weihua Guan, Fernando Rivadeneira, Wendy L McArdle, P Eline Slagboom, Tanja Zeller, Bruce M Psaty, André G Uitterlinden, Eco J C de Geus, David J Stott, Harald Binder, Albert Hofman, Oscar H Franco, Jerome I Rotter, Luigi Ferrucci, Tim D Spector, Ian J Deary, Winfried März, Andreas Greinacher, Philipp S Wild, Francesco Cucca, Dorret I Boomsma, Hugh Watkins, Weihong Tang, Paul M Ridker, Jan W Jukema, Rodney J Scott, Paul Mitchell, Torben Hansen, Christopher J O'Donnell, Nicholas L Smith, David P Strachan, Abbas Dehghan

Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0167742 (2017)

An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associa

Externí odkaz: https://doaj.org/article/747b3e99f9484bed947ca09451fdbbf2

Prognostic utility of Fibrosis-4 Index for risk of subsequent liver and cardiovascular events, and all-cause mortality in individuals with obesity and/or type 2 diabetes: a longitudinal cohort studyResearch in context panel

Autor: Quentin M. Anstee, Tina L. Berentzen, Louise M. Nitze, Maximilian Jara, Anders B. Jensen, Mette S. Kjær, Kamal K. Mangla, Jens M. Tarp, Kamlesh Khunti

Publikováno v: The Lancet Regional Health. Europe, Vol 36, Iss , Pp 100780- (2024)

Summary: Background: The Fibrosis-4 Index (FIB-4) is used as a non-invasive tool for the presence of advanced liver fibrosis in metabolic dysfunction-associated steatotic liver disease and type 2 diabetes. However, evidence for an association between

Externí odkaz: https://doaj.org/article/c488c2956e07421ba7c561883a9cc720

Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study

Autor: Graciela E. Delgado, Alanna C. Morrison, Jie Huang, Toshiko Tanaka, Karl J. Lackner, Torben Hansen, Magdalena Zoledziewska, Jan W. Jukema, Antonella Mulas, Gordon D.O. Lowe, Philipp S. Wild, Maria Sabater-Lleal, Weihua Guan, David P. Strachan, Johanna Mazur, Paul Mitchell, Stefania Bandinelli, Cristina Venturini, Albert Hofman, Daniel I. Chasman, Paul M. Ridker, Pirro G. Hysi, Fernando Rivadeneira, Kent D. Taylor, P. Eline Slagboom, Massimo Mangino, Jouke J. Hottenga, Vera Grossmann, Maristella Steri, Ian J. Deary, Paul S. de Vries, Ann Rumley, Mark McEvoy, Marcus E. Kleber, Tarunveer S. Ahluwalia, Christopher Oldmeadow, Riccardo E. Marioni, Lynda M. Rose, Harald Binder, Naveed Sattar, Anton J. M. de Craen, René Pool, Francesco Cucca, Saonli Basu, Jie Jin Wang, Oscar H. Franco, Elizabeth G. Holliday, Stella Trompet, Rodney J. Scott, Moniek P.M. de Maat, Winfried März, Annette Kifley, Wendy L. McArdle, Alexander Teumer, Nicholas L. Smith, Eco J. C. de Geus, John M. Starr, Christopher J. O'Donnell, John Attia, Bruce M. Psaty, Mattias Frånberg, Uwe Völker, Tim D. Spector, Harmen H.M. Draisma, Tanja Zeller, Symen Ligthart, Dorret I. Boomsma, Anders Hamsten, Qiong Yang, Barbara McKnight, André G. Uitterlinden, Lu-Chen Weng, Weihong Tang, Geoffrey H. Tofler, Hugh Watkins, Tina L. Berentzen, David J. Stott, Jerome I. Rotter, Anne Grotevendt, Jennifer A. Brody, Lorna M. Lopez, Abbas Dehghan, Luigi Ferrucci, Andreas Greinacher, Dena G. Hernandez, Ming-Huei Chen

Publikováno v: PLoS One (print), 12(1):e0167742. Public Library of Science
de Vries, P S, Sabater-Lleal, M, Chasman, D I, Trompet, S, Ahluwalia, T S, Teumer, A, Kleber, M E, Chen, M-H, Wang, J J, Attia, J R, Marioni, R E, Steri, M, Weng, L-C, Pool, R, Grossmann, V, Brody, J A, Venturini, C, Tanaka, T, Rose, L M, Oldmeadow, C, Mazur, J, Basu, S, Frånberg, M, Yang, Q, Ligthart, S, Hottenga, J J, Rumley, A, Mulas, A, De Craen, A J M, Grotevendt, A, Taylor, K D, Delgado, G E, Kifley, A, Lopez, L M, Berentzen, T L, Mangino, M, Bandinelli, S, Morrison, A C, Hamsten, A, Tofler, G, de Maat, M P M, Draisma, H H M, Lowe, G D, Zoledziewska, M, Sattar, N, Lackner, K J, Völker, U, McKnight, B, Huang, J, Holliday, E G, McEvoy, M A, Starr, J M, Hysi, P G, Hernandez, D G, Guan, W, Rivadeneira, F, McArdle, W L, Slagboom, P E, Zeller, T, Psaty, B M, Uitterlinden, A G, de Geus, E J C, Stott, D J, Binder, H, Hofman, A, Franco, O H, Rotter, J I, Ferrucci, L, Spector, T D, Deary, I J, März, W, Greinacher, A, Wild, P S, Cucca, F, Boomsma, D I, Watkins, H, Tang, W, Ridker, P M, Jukema, J W, Scott, R J, Mitchell, P, Hansen, T, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2017, ' Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study ', PLoS ONE, vol. 12, no. 1, e0167742, pp. e0167742 . https://doi.org/10.1371/journal.pone.0167742
De Vries, P S, Sabater-Lleal, M, Chasman, D I, Trompet, S, Ahluwalia, T S, Teumer, A, Kleber, M E, Chen, M H, Wang, J J, Attia, J R, Marioni, R E, Steri, M, Weng, L C, Pool, R, Grossmann, V, Brody, J A, Venturini, C, Tanaka, T, Rose, L M, Oldmeadow, C, Mazur, J, Basu, S, Frånberg, M, Yang, Q, Ligthart, S, Hottenga, J J, Rumley, A, Mulas, A, De Craen, A J M, Grotevendt, A, Taylor, K D, Delgado, G E, Kifley, A, Lopez, L M, Berentzen, T L, Mangino, M, Bandinelli, S, Morrison, A C, Hamsten, A, Tofler, G, De Maat, M P M, Draisma, H H M, Lowe, G D, Zoledziewska, M, Sattar, N, Lackner, K J, Völker, U, McKnight, B, Huang, J, Holliday, E G, McEvoy, M A, Starr, J M, Hysi, P G, Hernandez, D G, Guan, W, Rivadeneira, F, McArdle, W L, Slagboom, P E, Zeller, T, Psaty, B M, Uitterlinden, A G, De Geus, E J C, Stott, D J, Binder, H, Hofman, A, Franco, O H, Rotter, J I, Ferrucci, L, Spector, T D, Deary, I J, März, W, Greinacher, A, Wild, P S, Cucca, F, Boomsma, D I, Watkins, H, Tang, W, Ridker, P M, Jukema, J W, Scott, R J, Mitchell, P, Hansen, T, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2017, ' Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study ', PLoS ONE, vol. 12, no. 1, e0167742 . https://doi.org/10.1371/journal.pone.0167742
De Vries, P S, Sabater-Lleal, M, Chasman, D I, Trompet, S, Ahluwalia, T S, Teumer, A, Kleber, M E, Chen, M H, Wang, J J, Attia, J R, Marioni, R E, Steri, M, Weng, L C, Pool, R, Grossmann, V, Brody, J A, Venturini, C, Tanaka, T, Rose, L M, Oldmeadow, C, Mazur, J, Basu, S, Frånberg, M, Yang, Q, Ligthart, S, Hottenga, J J, Rumley, A, Mulas, A, De Craen, A J M, Grotevendt, A, Taylor, K D, Delgado, G E, Kifley, A, Lopez, L M, Berentzen, T L, Mangino, M, Bandinelli, S, Morrison, A C, Hamsten, A, Tofler, G, De Maat, M P M, Draisma, H H M, Lowe, G D, Zoledziewska, M, Sattar, N, Lackner, K J, Völker, U, McKnight, B, Huang, J, Holliday, E G, McEvoy, M A, Starr, J M, Hysi, P G, Hernandez, D G, Guan, W, Rivadeneira, F, McArdle, W L, Slagboom, P E, Zeller, T, Psaty, B M, Uitterlinden, A G, De Geus, E J C, Stott, D J, Binder, H, Hofman, A, Franco, O H, Rotter, J I, Ferrucci, L, Spector, T D, Deary, I J, März, W, Greinacher, A, Wild, P S, Cucca, F, Boomsma, D I, Watkins, H, Tang, W, Ridker, P M, Jukema, J W, Scott, R J, Mitchell, P, Hansen, T, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2017, ' Comparison of HapMap and 1000 genomes reference panels in a large-scale genome-wide association study ', PL o S One, vol. 12, no. 1, e0167742 . https://doi.org/10.1371/journal.pone.0167742
de Vries, P S, Sabater-Lleal, M, Chasman, D I, Trompet, S, Ahluwalia, T S, Teumer, A, Kleber, M E, Chen, M-H, Wang, J J, Attia, J R, Marioni, R E, Steri, M, Weng, L-C, Pool, R, Grossmann, V, Brody, J A, Venturini, C, Tanaka, T, Rose, L M, Oldmeadow, C, Mazur, J, Basu, S, Frånberg, M, Yang, Q, Ligthart, S, Hottenga, J J, Rumley, A, Mulas, A, de Craen, A J M, Grotevendt, A, Taylor, K D, Delgado, G E, Kifley, A, Lopez, L M, Berentzen, T L, Mangino, M, Bandinelli, S, Morrison, A C, Hamsten, A, Tofler, G, de Maat, M P M, Draisma, H H M, Lowe, G D, Zoledziewska, M, Sattar, N, Lackner, K J, Völker, U, McKnight, B, Huang, J, Holliday, E G, McEvoy, M A, Starr, J M, Hysi, P G, Hernandez, D G, Guan, W, Rivadeneira, F, McArdle, W L, Slagboom, P E, Zeller, T, Psaty, B M, Uitterlinden, A G, de Geus, E J C, Stott, D J, Binder, H, Hofman, A, Franco, O H, Rotter, J I, Ferrucci, L, Spector, T D, Deary, I J, März, W, Greinacher, A, Wild, P S, Cucca, F, Boomsma, D I, Watkins, H, Tang, W, Ridker, P M, Jukema, J W, Scott, R J, Mitchell, P, Hansen, T, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2017, ' Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study ', PLOS ONE, vol. 12, no. 1, e0167742 . https://doi.org/10.1371/journal.pone.0167742
PLoS ONE, 12(1)
de Vries, P S, Sabater-Lleal, M, Chasman, D I, Trompet, S, Ahluwalia, T S, Teumer, A, Kleber, M E, Chen, M-H, Wang, J J, Attia, J R, Marioni, R E, Steri, M, Weng, L-C, Pool, R, Grossmann, V, Brody, J A, Venturini, C, Tanaka, T, Rose, L M, Oldmeadow, C, Mazur, J, Basu, S, Frånberg, M, Yang, Q, Ligthart, S, Hottenga, J J, Rumley, A, Mulas, A, de Craen, A J M, Grotevendt, A, Taylor, K D, Delgado, G E, Kifley, A, Lopez, L M, Berentzen, T L, Mangino, M, Bandinelli, S, Morrison, A C, Hamsten, A, Tofler, G, de Maat, M P M, Draisma, H H M, Lowe, G D, Zoledziewska, M, Sattar, N, Lackner, K J, Völker, U, McKnight, B, Huang, J, Holliday, E G, McEvoy, M A, Starr, J M, Hysi, P G, Hernandez, D G, Guan, W, Rivadeneira, F, McArdle, W L, Slagboom, P E, Zeller, T, Psaty, B M, Uitterlinden, A G, de Geus, E J C, Stott, D J, Binder, H, Hofman, A, Franco, O H, Rotter, J I, Ferrucci, L, Spector, T D, Deary, I J, März, W, Greinacher, A, Wild, P S, Cucca, F, Boomsma, D I, Watkins, H, Tang, W, Ridker, P M, Jukema, J W, Scott, R J, Mitchell, P, Hansen, T, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2017, ' Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study ', PLoS ONE, vol. 12, no. 1, pp. e0167742 . https://doi.org/10.1371/journal.pone.0167742
PLoS ONE, 12(1):e0167742. Public Library of Science
PloS one, vol 12, iss 1
PLoS ONE, Vol 12, Iss 1, p e0167742 (2017)
PLoS ONE

An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e37d2f1380f91bb68e70f2c58266d3
https://eprints.gla.ac.uk/135064/1/135064.pdf

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

Autor: Riccardo E. Marioni, Christopher J. O'Donnell, Oscar H. Franco, Johan G. Eriksson, Francesco Cucca, Jonathan Marten, Alexander P. Reiner, Tim D. Spector, Philipp S. Wild, Paul Mitchell, Wolfgang Koenig, Barbara McKnight, J. Wouter Jukema, Alan F. Wright, Maria Sabater-Lleal, Charles Kooperberg, Albert Hofman, Talin Haritunians, Martina Müller-Nurasyid, Jie Huang, Jie Yao, Marcus E. Kleber, Pau Navarro, Nicholas L. Smith, Jennifer E. Huffman, Lynda M. Rose, Russell P. Tracy, Antti-Pekka Sarin, Stefania Bandinelli, Ian J. Deary, Aarno Palotie, Saonli Basu, Caroline Hayward, Kent D. Taylor, Winfried März, Aaron R. Folsom, Anne Grotevendt, Lawrence F. Bielak, Tarunveer S. Ahluwalia, Ming-Huei Chen, Alexander Teumer, Graciela E. Delgado, Sharon L.R. Kardia, Peter K. Joshi, Wendy L. McArdle, Toshiko Tanaka, Jing Hua Zhao, Diane M. Becker, Pierre-Emmanuel Morange, Alanna C. Morrison, Annette Kifley, Igor Rudan, Lorna M. Lopez, Kay-Tee Khaw, Nicholas J. Wareham, Eco J. C. de Geus, Mohsen Ghanbari, Jari Lahti, Tatijana Zemunik, John M. Starr, Magdalena Zoledziewska, Anuj Goel, Dena G. Hernandez, Abbas Dehghan, Ozren Polasek, Melanie Waldenberger, Helene Riess, Rodney J. Scott, Qiong Yang, Robert A. Scott, Nancy S. Jenny, Johanna Mazur, Weihong Tang, Paul M. Ridker, Torben Hansen, Anders Hamsten, James F. Wilson, Jouke J. Hottenga, Cristina Venturini, Paul L. Auer, Geoffrey H. Tofler, Pirro G. Hysi, Mark G. Mcevoy, Ann Rumley, Fernando Rivadeneira, Naveed Sattar, Ivana Kolcic, Jie Jin Wang, Jingmin Liu, Stella Trompet, Elizabeth G. Holliday, Sarah H. Wild, Maristella Steri, Uwe Völker, Tanja Zeller, Patricia A. Peyser, P. Eline Slagboom, Massimo Mangino, André G. Uitterlinden, Paul S. de Vries, Dorret I. Boomsma, Harry Campbell, Vera Grossmann, Gonneke Willemsen, Katri Räikkönen, Edoardo Fiorillo, Ares Rocanin-Arjo, Gordon D.O. Lowe, David P. Strachan, Anton J. M. de Craen, Moniek P.M. de Maat, David-Alexandre Trégouët, Jennifer A. Brody, Rehan Qayyum, Lisa R. Yanek, Luigi Ferrucci, Andreas Greinacher, Lewis C. Becker, Hugh Watkins, David J. Stott, Min A. Jhun, Tina L. Berentzen, Annette Peters, Bengt Sennblad, Daniel I. Chasman, Lihong Qi, Christopher Oldmeadow, Harald Binder, Xiuqing Guo, John Attia, Bruce M. Psaty

Publikováno v: Human Molecular Genetics, 25(2), 358-370
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2015, 25 (2), pp.358-370. ⟨10.1093/hmg/ddv454⟩
Human Molecular Genetics, 25(2), 358-370. Oxford University Press
de Vries, P S, Chasman, D I, Sabater-Lleal, M, Chen, M H, Huffman, J E, Steri, M, Tang, W, Teumer, A, Marioni, R E, Grossmann, V, Hottenga, J J, Willemsen, G, de Geus, E J C, Boomsma, D I, Cucca, F, Tracy, R, Watkins, H, Reiner, A P, Folsom, A R, Ridker, P M, O'Donnell, C J, Smith, N L, Strachan, D P & Dehghan, A 2016, ' A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration ', Human Molecular Genetics, vol. 25, no. 2, pp. 358-370 . https://doi.org/10.1093/hmg/ddv454

Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better covera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd6ce9c52e253d0a5d0162a8a3295cc
http://hdl.handle.net/1887/112436

Track 1 – Track 5

Autor: Claus Holst, Søren Toubro, Sofia I. Iqbal Kring, T. Jess, Tina L. Berentzen, T.P. Hansen, Esther Zimmermann, Arne Astrup, O. Pedersen, Thorkild I.A. Sørensen

Publikováno v: International Journal of Obesity. 32:S36-S234

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff2586fa7d9aaaaa5662758118ba89c3
https://doi.org/10.1038/ijo.2008.47