Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tina L, Gumienny"'
Publikováno v:
eLife, Vol 12 (2023)
Generating specific, robust protective responses to different bacteria is vital for animal survival. Here, we address the role of transforming growth factor β (TGF-β) member DBL-1 in regulating signature host defense responses in Caenorhabditis ele
Externí odkaz:
https://doaj.org/article/151a8960094a45dcbb5c81759dd2c212
Publikováno v:
Journal of visualized experiments : JoVE. (184)
Genomic DNA extraction from single or a few Caenorhabditis elegans has many downstream applications, including PCR for genotyping lines, cloning, and sequencing. The traditional proteinase K-based methods for genomic DNA extraction from C. elegans ta
Autor:
Sonja L. B. Arneaud, Jacob McClendon, Lexus Tatge, Abigail Watterson, Kielen R. Zuurbier, Bhoomi Madhu, Tina L. Gumienny, Peter M. Douglas
Publikováno v:
Aging cell. 21(9)
Aging is a complex and highly regulated process of interwoven signaling mechanisms. As an ancient transcriptional regulator of thermal adaptation and protein homeostasis, the Heat Shock Factor, HSF-1, has evolved functions within the nervous system t
Publikováno v:
Journal of Visualized Experiments.
Autor:
Cathy Savage-Dunn, Albar Chowdhury, Tina L. Gumienny, Shahrear Ahmed, Emma J. Ciccarelli, Uday Madaan, Lionel Faure
Publikováno v:
Molecular Biology of the Cell
Cellular responsiveness to environment, including changes in extracellular matrix (ECM), is critical for normal processes such as development and wound healing, but can go awry, as in oncogenesis and fibrosis. One type of molecular pathway contributi
Autor:
Mehul Vora, Tina L. Gumienny, Richard W. Padgett, Bhoomi Madhu, Lionel Faure, Mohammed Farhan Lakdawala
Publikováno v:
Molecular Biology of the Cell
Bone morphogenetic protein (BMP) signaling pathways control many developmental and homeostatic processes, including cell size and extracellular matrix remodeling. An understanding of how this pathway itself is controlled remains incomplete. To identi
Innate immunity in animals is orchestrated by multiple cell signaling pathways, including the TGF-β superfamily pathway. While the role of TGF-β signaling in innate immunity has been clearly identified, the requirement for this pathway in generatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f45df497c7b2c288a4eb69a50ddcd8d
https://doi.org/10.1101/2021.03.30.437693
https://doi.org/10.1101/2021.03.30.437693
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101929 (2014)
In mammals, Bone Morphogenetic Protein (BMP) pathway signaling is important for the growth and homeostasis of extracellular matrix, including basement membrane remodeling, scarring, and bone growth. A conserved BMP member in Caenorhabditis elegans, D
Externí odkaz:
https://doaj.org/article/416b4957938248e189c192ff6a5c15b0
Autor:
Tina L. Gumienny, Bhoomi Madhu
Publikováno v:
SSRN Electronic Journal.
Generating specific, robust innate immune responses to different bacteria is vital for animal survival. Here, we address the role of transforming growth factor β (TGF- β) DBL-1 in regulating signature host defense responses in Caenorhabditis elegan
Publikováno v:
Genes Immun
Animals counter specific environmental challenges with a combination of broad and tailored host responses. One protein family enlisted in the innate immune response includes the saposin-like antimicrobial proteins. We investigated the expression of a