Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Tina Jaskoll"'
Autor:
Michael Melnick, Tina Jaskoll
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 103:573-582
Background Congenital cytomegalovirus infection is the major nongenetic cause of sensorineural hearing loss at birth and beyond. Among other pathologies, there is a striking dysplasia/hyperplasia of organ of Corti hair and supporting cells. Methods U
Autor:
Tina Jaskoll, Pablo Bringas, George Abichaker, Khine Htet, Scott Morita, Michael Melnick, Parish P. Sedghizadeh
Publikováno v:
Cells Tissues Organs. 192:221-239
Of the approximately 8,400 children born each year in the US with cytomegalovirus (CMV)-induced birth defects, more than one third exhibit hypoplasia and hypocalcification of tooth enamel. Our prior studies indicated that CMV severely delayed, but di
Publikováno v:
The Anatomical Record. :322-331
Hypohidrotic (anhidrotic) ectodermal dysplasia (HED), the most common of the approximately 150 described ectodermal dysplasias, is a disorder characterized by abnormal hair, teeth, sweat glands, and salivary glands. Mutations in the EDA (ectodysplasi
Autor:
Michael, Melnick, Tina, Jaskoll
Publikováno v:
Birth defects research. Part A, Clinical and molecular teratology. 103(7)
Congenital cytomegalovirus infection is the major nongenetic cause of sensorineural hearing loss at birth and beyond. Among other pathologies, there is a striking dysplasia/hyperplasia of organ of Corti hair and supporting cells.Using an in vitro emb
Publikováno v:
Cells Tissues Organs. 168:233-245
Interleukin-6 (IL-6) is a multifunctional cytokine that mediates cell growth, differentiation, and survival. It was the objective of the present study to investigate the possible function(s) of IL-6 signaling in embryonic mouse submandibular salivary
Publikováno v:
The Anatomical Record. 262:318-330
TNF is a pleiotropic cytokine that modulates cell proliferation and apoptosis. The objective of the present study was to investigate the possible function(s) of the TNF/TNF-R1 signaling pathway in embryonic mouse submandibular salivary gland (SMG) mo
Autor:
Michael Melnick, Tina Jaskoll
Publikováno v:
The Anatomical Record. 256:252-268
Branching morphogenesis of the mouse submandibular gland (SMG) is dependent on cell-cell conversations between and within epithelium and mesenchyme. Such conversations are typically mediated in other branching organs (lung, mammary glands, etc.) by h
Publikováno v:
Mechanisms of Development. 74:179-183
Mouse submandibular salivary gland (SMG) mucin is the primary histodifferentiation product of submandibular epithelia. We demonstrate marked differences between embryonic, neonatal, and adult SMG mucin mRNA and protein by Northern and Western blot an
Publikováno v:
Teratology. 54:34-44
Glucocorticoids (CORT) have been shown to induce cleft palate in mice. Although the pathogenetic pathway of CORT-induced cleft palate has been investigated for several decades, the molecular details remain to be elucidated. Since growth factors have
Publikováno v:
Molecular Reproduction and Development. 44:159-170
Embryonic lung maturation in the H-2 congenic pair, B10.A and B10, proceeds at different rates. The dependence of this heterochronic development on maternal haplotype suggests the involvement of a parentally imprinted gene. Since B10.A (H-2a) and B10