Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tina J. Boeld"'
Autor:
Petra Hoffmann, Christin Riegel, Kristina Doser, Tina J. Boeld, Matthias Edinger, Elisabeth Huber
Publikováno v:
Leukemia
Acute graft-versus-host disease (aGvHD) is a frequent complication after allogeneic bone marrow/stem cell transplantation (BMT/SCT) induced by co-transplanted alloreactive conventional donor T cells. We previously demonstrated that the adoptive trans
Autor:
Christian Schmidl, Tina J. Boeld, Michael Rehli, Petra Hoffmann, Matthias Edinger, Maja Klug, Reinhard Andreesen
Publikováno v:
Genome Research. 19:1165-1174
DNA methylation participates in establishing and maintaining chromatin structures and regulates gene transcription during mammalian development and cellular differentiation. With few exceptions, research thus far has focused on gene promoters, and li
Autor:
Andreas Grützkau, Petra Hoffmann, Alf Hamann, Tina J. Boeld, Jun Dong, Jochen Huehn, Matthias Edinger, Udo Baron, Stefan Floess, Sven Olek, Andreas Thiel, Ivana Türbachova, Georg Wieczorek, Katrin Baumann
Publikováno v:
European Journal of Immunology. 37:2378-2389
The transcription factor FOXP3 is critical for development and function of regulatory T cells (Treg). Their number and functioning appears to be crucial in the prevention of autoimmunity and allergy, but also to be a negative prognostic marker for va
Publikováno v:
Microbes and Infection. 7:1066-1072
Graft-versus-host disease is a major complication after allogeneic bone marrow transplantation (BMT) caused by donor T cells. Immunosuppression mediated by CD4+CD25+ regulatory T cells has been shown to ameliorate such pathogenic immune responses in
Autor:
Tina J. Boeld, Matthias Edinger, Michael Rehli, Reinhard Andreesen, Petra Hoffmann, Christian Schmidl, Leo Hansmann
Publikováno v:
European journal of immunology. 40(5)
Autor:
Wolfgang Dietmaier, Tina J. Boeld, Georg Wieczorek, Jochen Huehn, Petra Hoffmann, Reinhard Andreesen, Ruediger Eder, Matthias Edinger, Sven Olek, Stefan Floess
Publikováno v:
European journal of immunology. 39(4)
The adoptive transfer of CD4(+)CD25(+) natural regulatory T cells (Treg) is a promising strategy for the treatment of autoimmune diseases and the prevention of alloresponses after transplantation. Clinical trials exploring this strategy require effic
Autor:
Matthias Edinger, Biserka Piseshka, Tina J. Boeld, Kristina Doser, Petra Hoffmann, Reinhard Andreesen, Ruediger Eder
Publikováno v:
Blood. 108(13)
Thymus-derived CD4+CD25+ regulatory T cells suppress autoreactive CD4+ and CD8+ T cells and thereby protect from autoimmunity. In animal models, adoptive transfer of CD4+CD25+ regulatory T cells has been shown to prevent and even cure autoimmune dise
Autor:
Matthias Edinger, Claudia Niemand, Kristina Doser, Tina J. Boeld, Petra Hoffmann, Mario Assenmacher, Evelyn Orsó, Biserka Piseshka, Ruediger Eder, Ernst Holler, Ashraf Dada, Julia Albrecht, Reinhard Andreesen
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 12(3)
The adoptive transfer of donor CD4+CD25+ regulatory T cells has been shown to protect from lethal graft-versus-host disease after allogeneic bone marrow transplantation in murine disease models. Efficient isolation strategies that comply with good ma
Autor:
Kristina Doser, Reinhard Andreesen, Martin Heidenreich, Petra Hoffmann, Tina J. Boeld, Matthias Edinger
Publikováno v:
Blood. 118:2976-2976
Abstract 2976 Graft-versus-host disease (GVHD) and infectious complications are main causes of non-relapse mortality after allogeneic stem cell transplantation (SCT). Impaired immune function after SCT is usually attributed to the immunosuppressive m
Publikováno v:
Blood. 112:4609-4609
In murine disease models, the adoptive transfer of donor CD4+CD25+ regulatory T cells (Treg) prevents lethal graft-versus-host disease (GVHD) after allogeneic bone marrow transplantation. We recently described methods for the isolation and in vitro e