Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tina Holt"'
Autor:
Yongbo Xue, Andrei I. Savchenko, Kylie A. Agnew-Francis, Jared A. Miles, Tina Holt, Hieng Lu, Sharon Chow, Paul I. Forster, Glen M. Boyle, Benjamin P. Ross, Katja Fischer, Andrei G. Kutateladze, Craig M. Williams
Publikováno v:
Journal of Natural Products. 86:490-497
Publikováno v:
Chirality
This manuscript describes predicted NMR shifts for the limonoid natural product xylogranatin F. The (1)H and (13)C NMR shifts of four diastereomers were evaluated by GIAO and hybrid DFT/parametric DU8+ methods. The results of the (1)H and (13)C NMR c
Publikováno v:
The Journal of Organic Chemistry. 84:7575-7586
Analysis of published NMR data for natural products containing the oxetane moiety, with the help of a recently developed parametric/DFT hybrid computational method DU8+, has revealed that oxetanes and related compounds constitute yet another signific
Autor:
Elena B. Averina, Kseniya N. Sedenkova, Tina Holt, Yulia A. Gracheva, Victor B. Rybakov, Elena V. Kharitonoshvili, Tamara S. Kuznetsova, Julia V. Kolodyazhnaya, Alexey A. Chistov, Andrei G. Kutateladze, Dmitry A. Vasilenko, Yuri K. Grishin, Elena R. Milaeva
Publikováno v:
Dyes and Pigments. 164:72-81
Pyrimidine N-oxide moiety for the first time was used as a heterocyclic core for the construction of π-conjugated molecules with fluorescent properties. For the synthesis of the title compounds a simple two-step protocol starting from readily availa
Publikováno v:
Mendeleev Communications. 31:300-301
DU8+ calculations of 13C NMR chemical shifts suggested that the structures of isoserrins A, B, and D – which were recently isolated from medicinal plant Isodon serra – are misassigned. Computationally driven structure revisions are presented in t
Autor:
Andrei G. Kutateladze, Tina Holt, D. Sai Reddy, Deepak B Huple, Michael T. Crimmins, Lyndon M. West, Abimael D. Rodríguez
Publikováno v:
The Journal of organic chemistry. 85(9)
Briarellins, a subset of C2-C11 cyclized cembranoids, were proposed to contain a C3-C14 ether or lactone bridge, similar to asbestinins. However, the total synthesis of the proposed structure of briarellin J revealed a misassignment. We revisited bri
Autor:
Paul Reddell, Craig M. Williams, Lidia A. Maslovskaya, Elizabeth H. Krenske, Andrei G. Kutateladze, Tina Holt, Sharon Chow, Andrei I. Savchenko, Glen M. Boyle, Victoria A. Gordon, Peter G. Parsons, Carly J. Pierce
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(51)
Structurally unique halimanes EBC-232 and EBC-323, isolated from the Australian rainforest plant Croton insularis, proved considerably difficult to elucidate. The two diastereomers, which consist an unusual oxo-6,7-spiro ring system fused to a dihydr
Addressing the Challenges of Structure Elucidation in Natural Products Possessing the Oxirane Moiety
Publikováno v:
The Journal of Organic Chemistry. 83:8341-8352
NMR data for natural products containing the epoxy moiety have been revisited and reanalyzed with the help of a recently developed parametric/DFT hybrid computational method, DU8+. More than 20 structures needed revision, which points to challenges i
Autor:
Andrei G. Kutateladze, Tina Holt
Publikováno v:
The Journal of Organic Chemistry. 84:8297-8299
Total synthesis has been an effective and broadly practiced approach for structure validation (or revision) of complex natural products. It appears that computational methods for structure elucidation are gradually becoming a better alternative, bein
Autor:
Dmitry A. Vasilenko, Yulia A. Gracheva, Andrei G. Kutateladze, Kirill S. Sadovnikov, Irina V. Abdrashitova, Tamara S. Kuznetsova, Alexey V. Terekhin, Tina Holt, Yuri K. Grishin, Elena B. Averina, Kseniya N. Sedenkova, Elena R. Milaeva
Publikováno v:
Tetrahedron Letters. 61:151605
An unusual condensation reaction of 2-methyltetrahydroquinazoline N-oxides with aromatic aldehydes was found. The reaction of 4-cyano substituted heterocycles as well as the use of microwave irradiation for 4-morpholinyl substituted heterocycles resu