Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tina Haupt"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1002-1007 (2021)
Benzyl salicylate (BS) is a natural ingredient of essential oils and a widely used fragrance chemical. A number of in vitro screening studies have evaluated the estrogenic potential of BS with ambiguous results. Lack of dose-response information for
Externí odkaz:
https://doaj.org/article/58546729d6e241fd997292d5c2249fb8
Autor:
Barbara Birk, Marián Rucki, Sjoerd Verkaart, L. Nardelli, Tina Haupt, Hans Raabe, Andreas Natsch, Rishil Kathawala, Petra S. Kern, Robert Landsiedel, Cindy A. Ryan, Susanne N. Kolle, Nathalie Alépée, Walter M.A. Westerink, Britta Wareing
Publikováno v:
ALTEX. 37(4)
While the skin sensitization hazard of substances can be identified using non-animal methods, the classification of potency into UN GHS sub-categories 1A and 1B remains challenging. The kinetic direct peptide reactivity assay (kDPRA) is a modificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f4c2f9e64e6c36cd0e949cb1c65522
https://pubmed.ncbi.nlm.nih.gov/32521036
https://pubmed.ncbi.nlm.nih.gov/32521036
Autor:
Adrian Nordone, Lu Hostettler, Andreas Natsch, Remo P. Badertscher, Gregory M. Adamson, Heike Laue, Yumiko Weiner-Sekiya, Tina Haupt
Publikováno v:
Archives of toxicology. 94(12)
A number of para-substituted benzoic acids (p-BA) and chemicals metabolized to p-BA have been found to confer adverse effects in male rats on sperm viability, motility, and morphology. These effects are putatively associated with the metabolism of p-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6082b858d321802b9af99cdceb3017b4
https://pubmed.ncbi.nlm.nih.gov/33057782
https://pubmed.ncbi.nlm.nih.gov/33057782
Publikováno v:
ALTEX.
Several in vitro OECD test guidelines address key events 1-3 of the adverse outcome pathway for skin sensitization, but none are validated for sensitizer potency assessment. The reaction of sensitizing molecules with skin proteins is the molecular in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac02f3737b7b72a1ba9a5c22864f1049
https://doi.org/10.14573/altex.2004292
https://doi.org/10.14573/altex.2004292
Publikováno v:
Toxicological Sciences. 165:170-185
Cosmetic regulations prohibit animal testing for the purpose of safety assessment and recent registration, evaluation and authorization of chemicals guidance states that the local lymph node assay (LLNA) in mice shall only be conducted if in vitro da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72feeef98f9b89636b329ac699180cbc
https://doi.org/10.1093/toxsci/kfy135
https://doi.org/10.1093/toxsci/kfy135
Publikováno v:
Environmental Toxicology and Chemistry. 37:931-941
Testing for acute fish toxicity is an integral part of the environmental safety assessment of chemicals. A true replacement of primary fish tissue was recently proposed using cell viability in a fish gill cell line (RTgill-W1) as a means of predictin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7270d5815bfd799e6b3fffe73cbf5aea
https://doi.org/10.1002/etc.4027
https://doi.org/10.1002/etc.4027
Publikováno v:
Environmental toxicology and chemistry. 37(3)
Testing for acute fish toxicity is an integral part of the environmental safety assessment of chemicals. A true replacement of primary fish tissue was recently proposed using cell viability in a fish gill cell line (RTgill-W1) as a means of predictin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::019b473fa90040cab112b58b0578c037
https://pubmed.ncbi.nlm.nih.gov/29105821
https://pubmed.ncbi.nlm.nih.gov/29105821
Publikováno v:
Toxicological Sciences. 143:319-332
Three in vitro methods for the prediction of the skin sensitization hazard have been validated. However, predicting sensitizer potency is a key requirement for risk assessment. Here, we report a database of 312 chemicals tested in the KeratinoSens™
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad70ef697ff77b45733d13034359c2d7
https://doi.org/10.1093/toxsci/kfu229
https://doi.org/10.1093/toxsci/kfu229
Publikováno v:
Flavour and Fragrance Journal. 29:277-286
Upon prolonged exposure to air, limonene is prone to oxidation. Hydroperoxides formed upon oxidation are strong skin sensitizers in animal tests and give positive patch tests in human dermatitis patients. However, there is no analytical evidence indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b08e40156c2a2e5a9fcb3e5522d819d7
https://doi.org/10.1002/ffj.3210
https://doi.org/10.1002/ffj.3210
Autor:
Melanie Fischer, Theo L. Sinnige, Kristin Schirmer, Jiří Novák, Scott D. Dyer, Valentin von Niederhäusern, Andreas Natsch, Maria Thérése Hultman, Diana Coman Schmid, Tina Haupt, Anze Županič, Ludek Blaha, Marie Mlnaříková, Hilda Witters, P. Berckmans, Scott E. Belanger, Heike Laue, Knut Erik Tollefsen, Mary Jo Bernhard, Joop L. M. Hermens, Adam Lillicrap
Publikováno v:
Toxicological Sciences, 169 (2)
Toxicological Sciences
Toxicological Sciences, 169(2), 353. Oxford University Press
Toxicological Sciences
Toxicological Sciences, 169(2), 353. Oxford University Press
Predicting fish acute toxicity of chemicals in vitro is an attractive alternative method to the conventional approach using juvenile and adult fish. The rainbow trout (Oncorhynchus mykiss) cell line assay with RTgill-W1 cells has been designed for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dfb2a78a96bfbca718ada86b93e76c
https://hdl.handle.net/1874/397200
https://hdl.handle.net/1874/397200