Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Tina, Wahle"'
Autor:
Alfonso Schiavi, Claudia Cirotti, Lora-Sophie Gerber, Giulia Di Lauro, Silvia Maglioni, Priscila Yumi Tanaka Shibao, Sabrina Montresor, Janine Kirstein, Patrick Petzsch, Karl Köhrer, Roel P. F. Schins, Tina Wahle, Daniela Barilà, Natascia Ventura
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-22 (2023)
Abstract Alzheimer’s disease is the most common age-associated neurodegenerative disorder and the most frequent form of dementia in our society. Aging is a complex biological process concurrently shaped by genetic, dietary and environmental factors
Externí odkaz:
https://doaj.org/article/b943984ede4d4379a2a87b1088dc502b
Autor:
Adriana Sofranko, Tina Wahle, Julia Kolling, Harm J. Heusinkveld, Burkhard Stahlmecke, Martin Rosenbruch, Catrin Albrecht, Roel P. F. Schins
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background There is an increasing concern about the neurotoxicity of engineered nanomaterials (NMs). To investigate the effects of subchronic oral exposures to SiO2 and CeO2 NMs on Alzheimer’s disease (AD)-like pathology, 5xFAD transgenic
Externí odkaz:
https://doaj.org/article/3bcd6534d49d46fbb10c2f5360f01a66
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The NLRP3 inflammasome plays an important role in intestinal homeostasis as well as inflammation. However, in vivo studies investigating the role of the NLRP3 inflammasome in inflammatory bowel disease (IBD) report contrasting results, leaving it unc
Externí odkaz:
https://doaj.org/article/2feabaf62b1d4f0b87f1a50d87d2a09c
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
As with toxicology in general, major challenges have emerged in its subfield neurotoxicology regarding the testing of engineered nanomaterials (ENM). This is on the one hand due to their complex physicochemical properties, like size, specific surface
Externí odkaz:
https://doaj.org/article/ab384bfe8a384a5eb368c5d245085a97
Autor:
Gerrit Bredeck, Angela A. M. Kämpfer, Adriana Sofranko, Tina Wahle, Veronika Büttner, Catrin Albrecht, Roel P. F. Schins
Publikováno v:
Nanomaterials, Vol 11, Iss 10, p 2621 (2021)
The increasing use of engineered nanomaterials (ENM) in food has fueled the development of intestinal in vitro models for toxicity testing. However, ENM effects on intestinal mucus have barely been addressed, although its crucial role for intestinal
Externí odkaz:
https://doaj.org/article/30bf848f633e4ca285171afb13b10953
Autor:
Maja Hullmann, Catrin Albrecht, Damiën van Berlo, Miriam E. Gerlofs-Nijland, Tina Wahle, Agnes W. Boots, Jean Krutmann, Flemming R. Cassee, Thomas A. Bayer, Roel P. F. Schins
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-14 (2017)
Abstract Background Increasing evidence from toxicological and epidemiological studies indicates that the central nervous system is an important target for ambient air pollutants. We have investigated whether long-term inhalation exposure to diesel e
Externí odkaz:
https://doaj.org/article/b0c62015f660490993716ccc4dc3da7b
Autor:
Burkhard Stahlmecke, Catrin Albrecht, Tina Wahle, Angela A.M. Kämpfer, Gerrit Bredeck, Jérôme Ambroise, Dominique Lison, Roel P. F. Schins, Adriana Sofranko
Publikováno v:
Nanotoxicology. :1-17
Rodent studies on the effects of engineered nanomaterials (ENM) on the gut microbiome have revealed contradictory results. Our aim was to assess the effects of four well-investigated model ENM using a realistic exposure scenario. Two independent ad l
Autor:
Tina Wahle, Adriana Sofranko, Eleonora Scarcello, Isabelle Masson, Catrin Albrecht, Gerrit Bredeck, Mathias Busch, Paul Fokkens, John Boere, Flemming R Cassee, Roel P F Schins
Publikováno v:
Annals of Work Exposures and Health. 67:i61-i61
A growing number of epidemiological studies has linked exposure to traffic-related air pollution (TRAP) to neurological and neurodegenerative diseases. In a previous study, we showed that subchronic inhalation exposure to diesel engine exhaust, as a
Autor:
Gerrit, Bredeck, Angela A M, Kämpfer, Adriana, Sofranko, Tina, Wahle, Dominique, Lison, Jérôme, Ambroise, Burkhard, Stahlmecke, Catrin, Albrecht, Roel P F, Schins
Publikováno v:
Nanotoxicology. 15(7)
Rodent studies on the effects of engineered nanomaterials (ENM) on the gut microbiome have revealed contradictory results. Our aim was to assess the effects of four well-investigated model ENM using a realistic exposure scenario. Two independent
Autor:
Adriana, Sofranko, Tina, Wahle, Julia, Kolling, Harm J, Heusinkveld, Burkhard, Stahlmecke, Martin, Rosenbruch, Catrin, Albrecht, Roel P F, Schins
Publikováno v:
Particle and fibre toxicology. 19(1)
There is an increasing concern about the neurotoxicity of engineered nanomaterials (NMs). To investigate the effects of subchronic oral exposures to SiONo marked behavioural impairments were observed in the mice exposed to SiOThe findings from the pr