Triangulating evidence from observational and Mendelian randomization studies of ketone bodies for cognitive performance

Autor: Wichanon Sae-jie, Suangsuda Supasai, Mika Kivimaki, Jackie F. Price, Andrew Wong, Meena Kumari, Jorgen Engmann, Tina Shah, Amand F. Schmidt, Tom R. Gaunt, Aroon Hingorani, Pimphen Charoen, on behalf of the UCLEB Consortium

Publikováno v: BMC Medicine, Vol 21, Iss 1, Pp 1-10 (2023)

Abstract Background Ketone bodies (KBs) are an alternative energy supply for brain functions when glucose is limited. The most abundant ketone metabolite, 3-β-hydroxybutyrate (BOHBUT), has been suggested to prevent or delay cognitive impairment, but

Externí odkaz: https://doaj.org/article/8c2a1587763f421896685ace2f5449df

The Sustainability of the Impact of Pharmacists’ Educational Programs on the Adherence to the Recommendations of Preoperative Antibiotic Prophylaxis Guidelines

Autor: Maryam Mehrpooya, Maryam Rangchian, Tina Shah-Ebrahimi

Publikováno v: Current Drug Safety. 18:39-50

Introduction: This study was designed to evaluate the sustainability of the impact of educational programs provided by pharmacists on the appropriateness of surgical antibiotic prophylaxis and cost-savings in a short time and a long time after the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d743398eb5d06916969b52f00d05a9
https://doi.org/10.2174/1574886317999220405113744

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

Autor: Nora Franceschini, Claudia Giambartolomei, Paul S. de Vries, Chris Finan, Joshua C. Bis, Rachael P. Huntley, Ruth C. Lovering, Salman M. Tajuddin, Thomas W. Winkler, Misa Graff, Maryam Kavousi, Caroline Dale, Albert V. Smith, Edith Hofer, Elisabeth M. van Leeuwen, Ilja M. Nolte, Lingyi Lu, Markus Scholz, Muralidharan Sargurupremraj, Niina Pitkänen, Oscar Franzén, Peter K. Joshi, Raymond Noordam, Riccardo E. Marioni, Shih-Jen Hwang, Solomon K. Musani, Ulf Schminke, Walter Palmas, Aaron Isaacs, Adolfo Correa, Alan B. Zonderman, Albert Hofman, Alexander Teumer, Amanda J. Cox, André G. Uitterlinden, Andrew Wong, Andries J. Smit, Anne B. Newman, Annie Britton, Arno Ruusalepp, Bengt Sennblad, Bo Hedblad, Bogdan Pasaniuc, Brenda W. Penninx, Carl D. Langefeld, Christina L. Wassel, Christophe Tzourio, Cristiano Fava, Damiano Baldassarre, Daniel H. O’Leary, Daniel Teupser, Diana Kuh, Elena Tremoli, Elmo Mannarino, Enzo Grossi, Eric Boerwinkle, Eric E. Schadt, Erik Ingelsson, Fabrizio Veglia, Fernando Rivadeneira, Frank Beutner, Ganesh Chauhan, Gerardo Heiss, Harold Snieder, Harry Campbell, Henry Völzke, Hugh S. Markus, Ian J. Deary, J. Wouter Jukema, Jacqueline de Graaf, Jacqueline Price, Janne Pott, Jemma C. Hopewell, Jingjing Liang, Joachim Thiery, Jorgen Engmann, Karl Gertow, Kenneth Rice, Kent D. Taylor, Klodian Dhana, Lambertus A. L. M. Kiemeney, Lars Lind, Laura M. Raffield, Lenore J. Launer, Lesca M. Holdt, Marcus Dörr, Martin Dichgans, Matthew Traylor, Matthias Sitzer, Meena Kumari, Mika Kivimaki, Mike A. Nalls, Olle Melander, Olli Raitakari, Oscar H. Franco, Oscar L. Rueda-Ochoa, Panos Roussos, Peter H. Whincup, Philippe Amouyel, Philippe Giral, Pramod Anugu, Quenna Wong, Rainer Malik, Rainer Rauramaa, Ralph Burkhardt, Rebecca Hardy, Reinhold Schmidt, Renée de Mutsert, Richard W. Morris, Rona J. Strawbridge, S. Goya Wannamethee, Sara Hägg, Sonia Shah, Stela McLachlan, Stella Trompet, Sudha Seshadri, Sudhir Kurl, Susan R. Heckbert, Susan Ring, Tamara B. Harris, Terho Lehtimäki, Tessel E. Galesloot, Tina Shah, Ulf de Faire, Vincent Plagnol, Wayne D. Rosamond, Wendy Post, Xiaofeng Zhu, Xiaoling Zhang, Xiuqing Guo, Yasaman Saba, MEGASTROKE Consortium, Abbas Dehghan, Adrie Seldenrijk, Alanna C. Morrison, Anders Hamsten, Bruce M. Psaty, Cornelia M. van Duijn, Deborah A. Lawlor, Dennis O. Mook-Kanamori, Donald W. Bowden, Helena Schmidt, James F. Wilson, James G. Wilson, Jerome I. Rotter, Joanna M. Wardlaw, John Deanfield, Julian Halcox, Leo-Pekka Lyytikäinen, Markus Loeffler, Michele K. Evans, Stéphanie Debette, Steve E. Humphries, Uwe Völker, Vilmundur Gudnason, Aroon D. Hingorani, Johan L. M. Björkegren, Juan P. Casas, Christopher J. O’Donnell

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

Carotid intima-media thickness (cIMT) and plaque are associated with subclinical atherosclerosis and coronary heart disease (CHD). Here, the authors identify and prioritize genetic loci for cIMT and plaque by GWAS and colocalization approaches and fu

Externí odkaz: https://doaj.org/article/32fac89a43804269804a3e18ff002db4

Orbital Pseudotumor as an Extrahepatic Complication of Chronic HCV Infection

Autor: Owen Huang, Tina Shah, Divya Sundarapandiyan, Matthew J. Akiyama

Publikováno v: Case Reports in Infectious Diseases, Vol 2018 (2018)

We present a patient who was admitted for eye swelling, pain, and discharge, with CT orbits with contrast demonstrating inflammation and enlargement of the lacrimal glands and surrounding tissue. He was found to have an HCV infection for unknown dura

Externí odkaz: https://doaj.org/article/483f3dbe62fb4d07bb8d771198637613

Meditation and Cardiovascular Risk ReductionA Scientific Statement From the American Heart Association

Autor: Glenn N. Levine, Richard A. Lange, C. Noel Bairey‐Merz, Richard J. Davidson, Kenneth Jamerson, Puja K. Mehta, Erin D. Michos, Keith Norris, Indranill Basu Ray, Karen L. Saban, Tina Shah, Richard Stein, Sidney C. Smith

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)

Abstract Despite numerous advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains a leading cause of morbidity and mortality. Novel and inexpensive interventions that can contribute to the primary and secondary pre

Externí odkaz: https://doaj.org/article/cd2523a6858e4768926be0a73d2980f7