Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tina, Bay"'
Publikováno v:
In International Journal of Greenhouse Gas Control November 2013 19:117-125
Autor:
Gitte M. Knudsen, Matthias M. Herth, Claus H. Jensen, Tina Bay, Rasmus P. Clausen, Szabolcs Lehel, Christoffer Bundgaard, Stine B. Vogensen, Bente Frølund, Petrine Wellendorph, Hanne D. Hansen, Louise Thiesen
Publikováno v:
ACS Chemical Neuroscience. 8:22-27
γ-Hydroxybutyric acid (GHB) is an endogenous neuroactive substance and proposed neurotransmitter with affinity for both low- and high-affinity binding sites. A radioligand with high and specific affinity toward the high-affinity GHB binding site wou
Autor:
Rasmus P. Clausen, Inge S. Villumsen, Anders B. Klein, Bente Frølund, Petrine Wellendorph, Gitte M. Knudsen, Aleš Marek, Hanne D. Hansen, Christina Birkedahl Falk-Petersen, Tina Bay
Publikováno v:
Neurochemistry International. 100:138-145
GHB (γ-hydroxybutyric acid) is a compound endogenous to mammalian brain with high structural resemblance to GABA. GHB possesses nanomolar-micromolar affinity for a unique population of binding sites, but the exact nature of these remains elusive. In
Autor:
Claus H, Jensen, Hanne D, Hansen, Tina, Bay, Stine B, Vogensen, Szabolcs, Lehel, Louise, Thiesen, Christoffer, Bundgaard, Rasmus P, Clausen, Gitte M, Knudsen, Matthias M, Herth, Petrine, Wellendorph, Bente, Frølund
Publikováno v:
ACS chemical neuroscience. 8(1)
γ-Hydroxybutyric acid (GHB) is an endogenous neuroactive substance and proposed neurotransmitter with affinity for both low- and high-affinity binding sites. A radioligand with high and specific affinity toward the high-affinity GHB binding site wou
Publikováno v:
International Journal of Greenhouse Gas Control. 19:117-125
The consequences of CO2 leakage from geological sequestration into shallow aquifers must be fully understood before such geo-engineering technology can be implemented. A series of CO2 exposure batch reactor experiments were conducted utilizing 8 sedi
Autor:
Hans Bräuner-Osborne, Rasmus P. Clausen, Bente Frølund, Nasiara Karim, Gitte M. Knudsen, Mary Chebib, Jesper V. Olsen, Laura F. Eghorn, Petrine Wellendorph, Nathan L. Absalom, Inge S. Villumsen, Tina Bay
Publikováno v:
Proceedings of the National Academy of Sciences. 109:13404-13409
γ-Hydroxybutyric acid (GHB) binding to brain-specific high-affinity sites is well-established and proposed to explain both physiological and pharmacological actions. However, the mechanistic links between these lines of data are unknown. To identify
Publikováno v:
The Journal of biological chemistry. 289(33)
The serotonin transporter (SERT) plays a critical role in regulating serotonin signaling by mediating reuptake of serotonin from the extracellular space. The molecular and cellular mechanisms controlling SERT levels in the membrane remain poorly unde
Autor:
Christoffer Bundgaard, Aleš Marek, Jan Kehler, Stine B. Vogensen, Martin Holst Friborg Pedersen, Rasmus P. Clausen, Bente Frølund, Petrine Wellendorph, Tina Bay
3-Hydroxycyclopent-1-enecarboxylic acid (HOCPCA, 1) is a potent ligand for the high-affinity GHB binding sites in the CNS. An improved synthesis of 1 together with a very efficient synthesis of [(3)H]-1 is described. The radiosynthesis employs in sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9932b2feafe07bad8bad8372ef83b610
https://europepmc.org/articles/PMC3888956/
https://europepmc.org/articles/PMC3888956/
Publikováno v:
Biochemical pharmacology. 87(2)
γ-Hydroxybutyric acid (GHB) is an endogenous compound in the mammalian brain with both low- and high-affinity receptor targets. GHB is used clinically in the treatment of symptoms of narcolepsy and alcoholism, but also illicitly abused as the recrea
Publikováno v:
Neuropharmacology. 57(3)
The human serotonin transporter (hSERT) is responsible for reuptake of serotonin (5-HT) from the synaptic cleft and is target for antidepressant medicine. Differential hSERT activity caused by genetic polymorphisms is believed to affect the risk of d